Etilefrine Pivalate
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Etilefrine pivalate ; developmental code name K-30052) is a sympathomimetic agent which was never marketed. It is the 3- pivalate
ester In chemistry, an ester is a compound derived from an acid (either organic or inorganic) in which the hydrogen atom (H) of at least one acidic hydroxyl group () of that acid is replaced by an organyl group (R). These compounds contain a distin ...
of
etilefrine Etilefrine, sold under the brand name Effortil among others, is a sympathomimetic medication used as an antihypotensive agent to treat orthostatic hypotension. It is usually used oral administration, by mouth, but is also available as an injecti ...
(ethylnorphenylephrine) and has much greater
lipophilicity Lipophilicity (from Greek λίπος "fat" and φίλος "friendly") is the ability of a chemical compound to dissolve in fats, oils, lipids, and non-polar solvents such as hexane or toluene. Such compounds are called lipophilic (translated ...
than etilefrine. Some related
compound Compound may refer to: Architecture and built environments * Compound (enclosure), a cluster of buildings having a shared purpose, usually inside a fence or wall ** Compound (fortification), a version of the above fortified with defensive struc ...
s include
pivenfrine Pivenfrine (), also known as pivalylphenylephrine or phenylephrine pivalate, is a sympathomimetic and mydriatic agent which was never marketed. It is the 3- pivalyl ester of phenylephrine. Pivenfrine has much greater lipophilicity than phenyleph ...
(phenylephrine pivalate) and
dipivefrine Dipivefrine, or dipivefrin, also known as epinephrine pivalate and sold under the brand name Propine among others, is a sympathomimetic medication which is used in the treatment of open-angle glaucoma.Dipivefrin . It is available as a 0.1% o ...
(epinephrine dipivalate), which were developed as mydriatic agents.


References

Alpha-1 adrenergic receptor agonists Alpha-2 adrenergic receptor agonists Beta-adrenergic agonists Phenylethanolamines Sympathomimetics {{Cardiovascular-drug-stub