Estrone benzoate, or estrone 3-benzoate, is a
synthetic Synthetic things are composed of multiple parts, often with the implication that they are artificial. In particular, 'synthetic' may refer to:
Science
* Synthetic chemical or compound, produced by the process of chemical synthesis
* Synthetic o ...
estrogen and
estrogen ester – specifically, the C3
benzoate
Benzoic acid is a white (or colorless) solid organic compound with the formula , whose structure consists of a benzene ring () with a carboxyl () substituent. It is the simplest aromatic carboxylic acid. The name is derived from gum benzoin, wh ...
ester of
estrone – which was first reported in 1932 and was never marketed.
It led to the development in 1933 of the more active
estradiol benzoate
Estradiol benzoate (EB), sold under the brand name Progynon-B among others, is an estrogen medication which is used in hormone therapy for menopausal symptoms and low estrogen levels in women, in hormone therapy for transgender women, and in the ...
, the first estradiol ester to be introduced for medical use.
See also
*
List of estrogen esters § Estrone esters
References
Abandoned drugs
Benzoate esters
Estrone esters
Ketones
Prodrugs
Synthetic estrogens
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