Estradiol dibutyrate (EDBu), or estradiol dibutanoate, is an
estrogen
Estrogen (also spelled oestrogen in British English; see spelling differences) is a category of sex hormone responsible for the development and regulation of the female reproductive system and secondary sex characteristics. There are three ...
medication and an
estrogen ester
An estrogen ester is an ester of an estrogen, most typically of estradiol but also of other estrogens such as estrone, estriol, and even nonsteroidal estrogens like diethylstilbestrol. Esterification renders estradiol into a prodrug of estradiol ...
– specifically, a
diester
In chemistry, an ester is a compound derived from an acid (either organic or inorganic) in which the hydrogen atom (H) of at least one acidic hydroxyl group () of that acid is replaced by an organyl group (R). These compounds contain a distinc ...
of
estradiol
Estradiol (E2), also called oestrogen, oestradiol, is an estrogen steroid hormone and the major female sex hormone. It is involved in the regulation of female reproductive cycles such as estrous and menstrual cycles. Estradiol is responsible ...
– which is no longer used.
It was a component of Triormon Depositum, a
combination
In mathematics, a combination is a selection of items from a set that has distinct members, such that the order of selection does not matter (unlike permutations). For example, given three fruits, say an apple, an orange and a pear, there are ...
formulation
Formulation is a term used in various senses in various applications, both the material and the abstract or formal. Its fundamental meaning is the putting together of components in appropriate relationships or structures, according to a formula ...
of estradiol dibutyrate,
testosterone caproate, and
hydroxyprogesterone heptanoate which was developed in the 1950s.
See also
*
List of estrogen esters § Estradiol esters
*
Estradiol dibutyrate/hydroxyprogesterone heptanoate/testosterone caproate
References
Abandoned drugs
Butyrate esters
Estradiol esters
Synthetic estrogens
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