Esmond Ray Long
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Esmond "Es" Ray Long (June 16, 1890 – November 11, 1979) was an American pathologist, epidemiologist, and medical historian. He was named emeritus professor of pathology at the
University of Pennsylvania The University of Pennsylvania (Penn or UPenn) is a Private university, private Ivy League research university in Philadelphia, Pennsylvania, United States. One of nine colonial colleges, it was chartered in 1755 through the efforts of f ...
and was the director of the Henry Phipps Institute for the Study, Treatment and Prevention of Tuberculosis from 1935 until 1955. Long served in the
United States Army Medical Corps The Medical Corps (MC) of the U.S. Army is a staff corps (non-combat specialty branch) of the U.S. Army Medical Department (AMEDD) consisting of commissioned medical officers – physicians with either an M.D. or a D.O. degree, at least o ...
during
World War II World War II or the Second World War (1 September 1939 – 2 September 1945) was a World war, global conflict between two coalitions: the Allies of World War II, Allies and the Axis powers. World War II by country, Nearly all of the wo ...
as director of the
tuberculosis Tuberculosis (TB), also known colloquially as the "white death", or historically as consumption, is a contagious disease usually caused by ''Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can al ...
program.


Biography

He was born in
Chicago, Illinois Chicago is the List of municipalities in Illinois, most populous city in the U.S. state of Illinois and in the Midwestern United States. With a population of 2,746,388, as of the 2020 United States census, 2020 census, it is the List of Unite ...
, the son of John Harper Long and Catherine Belle ''née'' Stoneman. His father was professor of chemistry at
Northwestern University Northwestern University (NU) is a Private university, private research university in Evanston, Illinois, United States. Established in 1851 to serve the historic Northwest Territory, it is the oldest University charter, chartered university in ...
, and a pioneer in physiological chemistry. Long completed his secondary education at
Morgan Park Academy Morgan Park Academy (MPA) is a coeducational, college preparatory, independent day school serving pre-kindergarten through 12th grade. It is located in the Morgan Park neighborhood on the south side of Chicago, Illinois. Founded in 1873, Morg ...
in 1906, then spent a year receiving private tutelage in chemistry from his father and others. He matriculated to the
University of Chicago The University of Chicago (UChicago, Chicago, or UChi) is a Private university, private research university in Chicago, Illinois, United States. Its main campus is in the Hyde Park, Chicago, Hyde Park neighborhood on Chicago's South Side, Chic ...
where he majored in chemistry. In 1909 he was a member of the university cross-country team, then he joined the track team in 1910, demonstrating his fitness at the time. Long was awarded his A. B. degree in 1911, then entered graduate school in the university's school of medicine. In 1913, during his second year as a medical student, Long had a severe
pulmonary hemorrhage Pulmonary hemorrhage (or pulmonary haemorrhage) is an acute bleeding from the lung, from the upper respiratory tract and the trachea, and the pulmonary alveoli. When evident clinically, the condition is usually massive.sputum Sputum is mucus that is coughed up from the lower airways (the trachea and bronchi). In medicine, sputum samples are usually used for a naked-eye examination, microbiological investigation of respiratory infections, and Cytopathology, cytological ...
, Long identified tubercle bacilli at his laboratory, indicating he had contracted active
tuberculosis Tuberculosis (TB), also known colloquially as the "white death", or historically as consumption, is a contagious disease usually caused by ''Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can al ...
(TB). He would spend the next six years undergoing various ineffective therapies for the condition, while studying and performing research on the disease. He would continue on this path of investigation for the next half century. During 1917–1918 and again in 1920 he was a Trudeau Fellow at the
Saranac Laboratory for the study of Tuberculosis Saranac may refer to a place name in the United States: * Saranac, Michigan, a village ;New York * Saranac, New York, a town in Clinton County * Saranac Lake, New York, a large village in Franklin and Essex counties * Upper Saranac Lake * Middle Sa ...
, working under its director
Edward R. Baldwin Edward R. Baldwin (September 8, 1864 – May 6, 1947) was an American bacteriologist. He was president of the American Clinical and Climatological Association in 1910 and the National Tuberculosis Association during 1916–1917. Biography He w ...
. Long received his Ph.D. in 1918 with a thesis titled, ''Some Phases of Normal and Abnormal
Purine Metabolism Purine metabolism refers to the metabolic pathways to synthesize and break down purines that are present in many organisms. Biosynthesis Purines are biologically synthesized as nucleotides and in particular as ribotides, i.e. bases attached to r ...
in Man and Domestic Animals''. In the summer of 1919, he worked as an intern at Saranac Lake Reception Hospital, providing assistance for patients while living out of a tent. The same year he had recovered sufficiently to join the department of pathology at the
University of Chicago The University of Chicago (UChicago, Chicago, or UChi) is a Private university, private research university in Chicago, Illinois, United States. Its main campus is in the Hyde Park, Chicago, Hyde Park neighborhood on Chicago's South Side, Chic ...
, working as an instructor. In 1921, Long was named assistant professor at the university. He spent the summer at Stanford University Medical School, working on a clinical study. On his return trip to Chicago in September he visited Marian Beak Adams in Denver, a distant relative. They were married on June 17, 1922, and would have a daughter, Judith Baird, and a son, Esmond R. Long Jr. Marian was a skilled pianist and taught piano students. The couple would honeymoon in
Vienna Vienna ( ; ; ) is the capital city, capital, List of largest cities in Austria, most populous city, and one of Federal states of Austria, nine federal states of Austria. It is Austria's primate city, with just over two million inhabitants. ...
,
Austria Austria, formally the Republic of Austria, is a landlocked country in Central Europe, lying in the Eastern Alps. It is a federation of nine Federal states of Austria, states, of which the capital Vienna is the List of largest cities in Aust ...
, where Long performed post-graduate research at the University of Prague under the Austrian pathologist
Anton Ghon Anton Ghon (1 January 1866 – 23 April 1936) was an Austrian pathologist and bacteriologist. He is best known for his research on tuberculosis ( Ghon's complex). Biography Ghon was born on January 1, 1866, in Villach. From 1884 to 1890, Gho ...
. The following year, Long would collaborate with Harry G. Wells and Lydia M. DeWitt to publish a book titled, ''The chemistry of Tuberculosis''. He was named associate professor in 1923. During his TB studies he frequently collaborated with his assistant, Florence Seibert. Together they isolated the protein which formed the active principle of TB. In 1926 Long received his M.D. from the
Rush Medical College Rush Medical College is the medical school of Rush University, a private research university in Chicago, Illinois. Established in 1837, it is affiliated with Rush University Medical Center, and John H. Stroger Jr. Hospital of Cook County. ...
, then part of the University of Chicago. In 1932, Long moved to Philadelphia with his family, where he became professor of pathology at the
University of Pennsylvania The University of Pennsylvania (Penn or UPenn) is a Private university, private Ivy League research university in Philadelphia, Pennsylvania, United States. One of nine colonial colleges, it was chartered in 1755 through the efforts of f ...
and a researcher at the Henry Phipps Institute for the Study, Treatment and Prevention of Tuberculosis, bringing with him Florence Seibert. In time, she was able to crystallize and purify the substance that served as basis of the PPD skin test used for TB screening to the present day. He became a member of the advisory committee on research for the Leonard Wood Memorial. In 1935 he was named head of the Phipps Institute, and would remain director until his retirement in 1955. From 1936 to 1939 he chaired the National Research Council's division of medical sciences. During 1936–1937 he was board chair for the
American Lung Association The American Lung Association is a voluntary health organization whose mission is to save lives by improving lung health and preventing lung disease through education, advocacy and research. History 1904–1918: Founding The organization was ...
. He was president of the Wistar Institute of Anatomy and Biology from 1939 until 1942. In 1938, he was president of the
American Association of Pathologists and Bacteriologists The American Association of Pathologists and Bacteriologists (AAPB) was an American national professional association established in 1901, devoted to fundamental science and academic medicine as distinct from clinical medicine. In 1976, they joined ...
. With
World War II World War II or the Second World War (1 September 1939 – 2 September 1945) was a World war, global conflict between two coalitions: the Allies of World War II, Allies and the Axis powers. World War II by country, Nearly all of the wo ...
under way, in 1940 the National Research Council asked Long to chair the tuberculosis subcommittee of the Division of Medical Sciences. After the U.S. entered the war in 1941, Long received a commission as Colonel in the
Medical Corps A medical corps is generally a military branch or staff corps, officer corps responsible for medical care for serving military personnel. Such officers are typically military physicians. List of medical corps The following organizations are exam ...
. He relocated to Washington D.C. with his family so he could work out of the Office of the
Surgeon General Surgeon general (: surgeons general) is a title used in several Commonwealth countries and most NATO nations to refer either to a senior military medical officer or to a senior uniformed physician commissioned by the government and entrusted with p ...
. As director of the U.S. army tuberculosis program, Long set up a screening program to keep tuberculosis out of the armed forces and oversaw TB research and treatment programs in the U.S. In 1945, he traveled to the Europe theater where he visited the Army medical personnel treating former prisoners at the
Buchenwald Buchenwald (; 'beech forest') was a German Nazi concentration camp established on Ettersberg hill near Weimar, Germany, in July 1937. It was one of the first and the largest of the concentration camps within the Altreich (Old Reich) territori ...
and
Dachau concentration camp Dachau (, ; , ; ) was one of the first concentration camps built by Nazi Germany and the longest-running one, opening on 22 March 1933. The camp was initially intended to intern Hitler's political opponents, which consisted of communists, s ...
s. Following the war, he organized the tuberculosis treatment program in
Allied-occupied Germany The entirety of Germany was occupied and administered by the Allies of World War II, from the Berlin Declaration on 5 June 1945 to the establishment of West Germany on 23 May 1949. Unlike occupied Japan, Nazi Germany was stripped of its sov ...
. From 1947 until 1952 he served as the executive secretary of the ''
American Review of Tuberculosis The ''American Journal of Respiratory and Critical Care Medicine'' is a biweekly peer-reviewed medical journal published by the American Thoracic Society. It covers the pathophysiology and treatment of diseases that affect the respiratory system, a ...
'', becoming editor-in-chief in 1948. He served as special editor of medicine for the '' Webster's International Dictionary'', second edition. Long officially retired in 1955 and the family moved to a retirement residence in
Pedlar Mills, Virginia Pedlar may refer to: *The British English form and original spelling of peddler Entertainment * '' The Pedlar'' (or ''The Wayfarer''), a painting by Hieronymus Bosch * '' The Isis Pedlar'', a novel * The Bold Pedlar and Robin Hood, a Child Ba ...
, but he remained active in his scientific interests long thereafter. In 1964, he succeeded H. W. Wade as editor of the ''International Journal of Leprosy''. The Long family returned to Philadelphia in 1966. Marian died of
leukemia Leukemia ( also spelled leukaemia; pronounced ) is a group of blood cancers that usually begin in the bone marrow and produce high numbers of abnormal blood cells. These blood cells are not fully developed and are called ''blasts'' or '' ...
in 1974, and Long died November 11, 1979 at a nursing home in
Devon, Pennsylvania Devon is a census-designated place (CDP) located in Easttown township in Chester County, Pennsylvania, United States. The population was 1,515 at the 2010 census. The area is part of the Philadelphia Main Line suburbs. History As of the 2000 ...
.


Awards and honors

* Youngest person to be awarded the Trudeau Medal by the
National Tuberculosis Association National may refer to: Common uses * Nation or country ** Nationality – a ''national'' is a person who is subject to a nation, regardless of whether the person has full rights as a citizen Places in the United States * National, Maryland, ce ...
(1932) * Honorary member of the Philadelphia County Medical Society (1937) * Elected to the
American Philosophical Society The American Philosophical Society (APS) is an American scholarly organization and learned society founded in 1743 in Philadelphia that promotes knowledge in the humanities and natural sciences through research, professional meetings, publicat ...
(1940) * Elected to the
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, NGO, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the ...
(1946) * Philadelphia Bok Award (1954) * Gold headed cane of the
American Association of Pathologists and Bacteriologists The American Association of Pathologists and Bacteriologists (AAPB) was an American national professional association established in 1901, devoted to fundamental science and academic medicine as distinct from clinical medicine. In 1976, they joined ...
(1971)


Bibliography

In addition to publishing nearly 300 articles and editorials, Long was the author (or co-author) of several books: * * * * * * *


References


External links

* * * {{DEFAULTSORT:Long, Esmond Ray 1890 births 1979 deaths Scientists from Chicago University of Chicago alumni Rush Medical College alumni University of Pennsylvania faculty United States Army Medical Corps officers Tuberculosis researchers American pathologists American epidemiologists American medical historians Members of the United States National Academy of Sciences Members of the American Philosophical Society ASIP gold-headed cane award