Esco may refer to the following people:
;Given name
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Esco Sarkkinen (1918–1998), American football player and coach
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Esco Haynes, American professional baseball player
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Esco Niblo Bowen (born 1893 – died 1959), American lawyer, judge and politician
*
Sigmund Esco Jackson (born 1951), American singer and musician
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William Esco Moerner (born 1953), American physical chemist and chemical physicist awarded Nobel Prize in Chemistry in 2014
;Surname
*
Lina Esco (born 1985), American actress
;Nickname
*
DJ Esco
William Seay Moore (born December 31, 1990) known professionally as DJ Esco, is an American DJ, record producer, record executive, and songwriter. He is best known for his 2016 single " Too Much Sauce" (featuring Future and Lil Uzi Vert), which pe ...
(born 1990), American DJ from Georgia
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Nas
Nas (born 1973) is the stage name of American rapper Nasir Jones.
Nas, NaS, or NAS may also refer to:
Aviation
* Nasair, a low-cost airline carrier and subsidiary based in Eritrea
* National Air Services, an airline in Saudi Arabia
** Nas Air (S ...
(born 1973), nicknamed Esco, American rapper
{{given name, type=both
Spanish-language surnames