Ernest Fourneau (4 October 1872 – 5 August 1949) was a French pharmacist who graduated in 1898 for the Paris university specialist in
medicinal chemistry
Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacy involved with drug design, designing and developing pharmaceutical medication, drugs. Medicinal chemistry involves the identification, ...
and
pharmacology
Pharmacology is the science of drugs and medications, including a substance's origin, composition, pharmacokinetics, pharmacodynamics, therapeutic use, and toxicology. More specifically, it is the study of the interactions that occur betwee ...
. He played a major role in the discovery of synthetic
local anesthetic
A local anesthetic (LA) is a medication that causes absence of all sensation (including pain) in a specific body part without loss of consciousness, providing local anesthesia, as opposed to a general anesthetic, which eliminates all sensati ...
s such as
amylocaine, as well as in the synthesis of
suramin. He authored more than two hundred scholarly works, and has been described as having "helped to establish the fundamental laws of chemotherapy that have saved so many human lives".
Fourneau was a pupil of Friedel and Moureu, and studied in the German laboratories of
Ludwig Gattermann in
Heidelberg
Heidelberg (; ; ) is the List of cities in Baden-Württemberg by population, fifth-largest city in the States of Germany, German state of Baden-Württemberg, and with a population of about 163,000, of which roughly a quarter consists of studen ...
,
Hermann Emil Fischer
Hermann Emil Louis Fischer (; 9 October 1852 – 15 July 1919) was a German chemist and List of Nobel laureates in Chemistry, 1902 recipient of the Nobel Prize in Chemistry. He discovered the Fischer esterification. He also developed the Fisch ...
in
Berlin
Berlin ( ; ) is the Capital of Germany, capital and largest city of Germany, by both area and List of cities in Germany by population, population. With 3.7 million inhabitants, it has the List of cities in the European Union by population withi ...
and
Richard Willstätter in
Munich
Munich is the capital and most populous city of Bavaria, Germany. As of 30 November 2024, its population was 1,604,384, making it the third-largest city in Germany after Berlin and Hamburg. Munich is the largest city in Germany that is no ...
.
He headed the research laboratory of
Poulenc Frères in
Ivry-sur-Seine from 1903 to 1911.
One of the products was a synthetic local anesthetic that was named Stovaine (
amylocaine).
This was a pun on the English translation of "fourneau" as "stove". (The same pun was used in the brand name of the drug
acetarsol, Stovarsol.)
Other important medicines were
antipyretic
An antipyretic (, from ''anti-'' 'against' and ' 'feverish') is a substance that reduces fever. Antipyretics cause the hypothalamus to override a prostaglandin-induced increase in temperature. The body then works to lower the temperature, which r ...
s.
In 1910 Fourneau accepted the directorship of the
Pasteur Institute
The Pasteur Institute (, ) is a French non-profit private foundation dedicated to the study of biology, micro-organisms, diseases, and vaccines. It is named after Louis Pasteur, who invented pasteurization and vaccines for anthrax and rabies. Th ...
's
medical chemistry section, with the condition that he maintained his ties with Poulenc Frères. He recruited
Germaine Benoit to work in the Institute as a new graduate.
He was a member of the
Académie Nationale de Médecine.
Bibliography
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References
Sources
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French biochemists
French pharmacologists
Knights of the Order of Agricultural Merit
Officers of the Order of Polonia Restituta
Complutense University of Madrid
Officers of the Legion of Honour
People from Biarritz
1872 births
1949 deaths
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