Erich Nigg (born 28 November 1952 in

Uster Uster ( High Alemannic: ''Uschter'') is a town and the capital of the Uster District in the Swiss canton of Zürich. It is the third largest town in the canton of Zürich, with almost 35,000 inhabitants, and is one of the twenty largest towns ...

) is a

Swiss Swiss may refer to: * the adjectival form of Switzerland * Swiss people Places * Swiss, Missouri *Swiss, North Carolina * Swiss, West Virginia * Swiss, Wisconsin Other uses * Swiss-system tournament, in various games and sports *Swiss Internati ...

cell biologist Cell biology (also cellular biology or cytology) is a branch of biology that studies the structure, function, and behavior of cells. All living organisms are made of cells. A cell is the basic unit of life that is responsible for the living a ...

Life

Erich Nigg received his PhD in 1980 from the

ETH Zürich (colloquially) , former_name = eidgenössische polytechnische Schule , image = ETHZ.JPG , image_size = , established = , type = Public , budget = CHF 1.896 billion (2021) , rector = Günther Dissertori , president = Joël Mesot , ac ...

(Biochemistry). Subsequently, he carried out research at the

University of California The University of California (UC) is a public land-grant research university system in the U.S. state of California. The system is composed of the campuses at Berkeley, Davis, Irvine, Los Angeles, Merced, Riverside, San Diego, San Fran ...

in San Diego, the ETH Zürich and the

Swiss Institute for Experimental Cancer Research The Swiss Institute for Experimental Cancer Research (ISREC, ) is a not-for-profit institution founded in 1964 and located in Épalinges, Switzerland. Since 1 January 2008, it is organized into two distinct entities: * The ISREC Foundation whos ...

(ISREC). From 1995 he was Professor of

Molecular Biology Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and phys ...

at the

University of Geneva The University of Geneva (French: ''Université de Genève'') is a public research university located in Geneva, Switzerland. It was founded in 1559 by John Calvin as a theological seminary. It remained focused on theology until the 17th centur ...

before he was appointed, in 1999, to a Directorship at the

Max Planck Institute of Biochemistry The Max Planck Institute of Biochemistry (MPIB) is a research institute of the Max Planck Society located in Martinsried, a suburb of Munich. The institute was founded in 1973 by the merger of three formerly independent institutes: the Max Planck ...

Martinsried Martinsried is one of Munich's two science suburbs. It is a section of Planegg municipality in the district of Munich in Bavaria, Germany. Martinsried is best known as the location of the Max Planck Institute of Biochemistry, the Max Plan ...

, Germany. From 2009 - 2018 was Erich Nigg Professor of Cell Biology and Director of the Biozentrum at the University of Basel, Switzerland.

Work

After early work on

biological membranes A biological membrane, biomembrane or cell membrane is a selectively permeable membrane that separates the interior of a cell from the external environment or creates intracellular compartments by serving as a boundary between one part of the ...

, the structure of the cell nucleus and mechanisms of intracellular signal transduction, Erich Nigg's research focused on the

cell cycle The cell cycle, or cell-division cycle, is the series of events that take place in a cell that cause it to divide into two daughter cells. These events include the duplication of its DNA ( DNA replication) and some of its organelles, and sub ...

. His studies contribute to our understanding of the segregation of human

chromosomes A chromosome is a long DNA molecule with part or all of the genetic material of an organism. In most chromosomes the very long thin DNA fibers are coated with packaging proteins; in eukaryotic cells the most important of these proteins are ...

during

cell division Cell division is the process by which a parent cell divides into two daughter cells. Cell division usually occurs as part of a larger cell cycle in which the cell grows and replicates its chromosome(s) before dividing. In eukaryotes, there ar ...

, the regulation of

mitosis In cell biology, mitosis () is a part of the cell cycle in which replicated chromosomes are separated into two new nuclei. Cell division by mitosis gives rise to genetically identical cells in which the total number of chromosomes is maint ...

, as well as the structure and function of human

centrosomes In cell biology, the centrosome (Latin centrum 'center' + Greek sōma 'body') (archaically cytocentre) is an organelle that serves as the main microtubule organizing center (MTOC) of the animal cell, as well as a regulator of cell-cycle prog ...

. This work is relevant to understanding diseases, because mitotic errors contribute to the genetic instability of cancer cells and centrosome abnormalities are known to cause disease (brain diseases and ciliopathies).

Awards and honors

* 1991: Elected Member of the

European Molecular Biology Organization The European Molecular Biology Organization (EMBO) is a professional, non-profit organization of more than 1,800 life scientists. Its goal is to promote research in life science and enable international exchange between scientists. It co-funds cour ...

(EMBO) * 1992: Friedrich Miescher Prize * 1993: Robert Wenner Prize for Cancer Research * 1998: Elected Member of the

Academia Europaea The Academia Europaea is a pan-European Academy of Humanities, Letters, Law, and Sciences. The Academia was founded in 1988 as a functioning Europe-wide Academy that encompasses all fields of scholarly inquiry. It acts as co-ordinator of Europea ...

* 2004:

Meyenburg Prize The Meyenburg Prize is awarded for outstanding achievements in cancer research by the Meyenburg Foundation in support of the German Cancer Research Center, Heidelberg (DKFZ), which is the largest biomedical research institution in Germany. The pri ...

of Wilhelm and Maria Meyenburg Foundation * 2009: Elected member of the European Academy of Cancer Sciences

External links

Prof. Dr. Erich A. Nigg, Emeritus

Biozentrum University of Basel

University of Basel

References

{{DEFAULTSORT:Nigg, Erich Living people University of California, San Diego alumni University of Geneva alumni Members of the European Molecular Biology Organization Biozentrum University of Basel People from Uster 1952 births Max Planck Institute directors