Aspirin
Aspirin, also known as acetylsalicylic acid (ASA), is a nonsteroidal anti-inflammatory drug (NSAID) used to reduce pain, fever, and/or inflammation, and as an antithrombotic. Specific inflammatory conditions which aspirin is used to treat in ...
/
meprobamate
Meprobamate—marketed as Miltown by Wallace Laboratories and Equanil by Wyeth, among others—is a carbamate derivative used as an anxiolytic drug. It was the best-selling minor tranquilizer for a time, but has largely been replaced by the benz ...
(trade name Equagesic ) is a
combination drug
A combination drug or a fixed-dose combination (FDC) is a medicine that includes two or more active ingredients combined in a single dosage form. Terms like "combination drug" or "combination drug product" can be common shorthand for a FDC pr ...
indicated for short-term pain treatment accompanied by
tension or
anxiety
Anxiety is an emotion which is characterized by an unpleasant state of inner turmoil
Turmoil may refer to:
* ''Turmoil'' (1984 video game), a 1984 video game released by Bug-Byte
* ''Turmoil'' (2016 video game), a 2016 indie oil tycoon video ...
in patients with
musculoskeletal disorders
Musculoskeletal disorders (MSDs) are injuries or pain in the human musculoskeletal system, including the joints, ligaments, muscles, nerves, tendons, and structures that support limbs, neck and back. MSDs can arise from a sudden exertion (e.g., l ...
or
tension headache
Tension headache, also known as stress headache, or tension-type headache (TTH), is the most common type of primary headache. The pain can radiate from the lower back of the head, the neck, eyes or other muscle groups in the body typically affecti ...
.
Adverse effects
Combinations
There also appears to be a combination with
ethoheptazine
Ethoheptazine (trade name Zactane) is an opioid analgesic from the phenazepane family. It was invented in the 1950s and is a ring expanded analogue of pethidine.
Ethoheptazine produces similar effects to other opioids, including analgesia, sedat ...
, an
opioid
Opioids are substances that act on opioid receptors to produce morphine-like effects. Medically they are primarily used for pain relief, including anesthesia. Other medical uses include suppression of diarrhea, replacement therapy for opioi ...
analgesic.
Problems
Equagesic was discontinued in the United States, possibly because of its toxic effects. Specifically, meprobamate. The Equagesic drug was credited with the sudden death of actor
Bruce Lee
Bruce Lee (; born Lee Jun-fan, ; November 27, 1940 – July 20, 1973) was a Hong Kong and American martial artist and actor. He was the founder of Jeet Kune Do, a hybrid martial arts philosophy drawing from different combat disciplines th ...
in 1973. Lee suffered a fatal hypersensitive reaction to one of the prescription drug's ingredients while working in Hong Kong.
References
Combination drugs
Analgesics
Aspirin
{{analgesic-stub