Epinastine (brand names Alesion, Elestat, Purivist, Relestat) is a second-generation

antihistamine Antihistamines are drugs which treat allergic rhinitis, common cold, influenza, and other allergies. Typically, people take antihistamines as an inexpensive, generic (not patented) drug that can be bought without a prescription and provides ...

and

mast cell stabilizer Mast cell stabilizers are medications used to prevent or treat certain allergic disorders. They block mast cell degranulation, stabilizing the cell and thereby preventing the release of histamine and related mediators. One suspected pharmacody ...

that is used in

eye drop Eye drops or eyedrops are liquid drops applied directly to the surface of the eye usually in small amounts such as a single drop or a few drops. Eye drops usually contain saline to match the salinity of the eye. Drops containing only saline ...

s to treat

allergic conjunctivitis Allergic conjunctivitis (AC) is Allergic Inflammation, inflammation of the conjunctiva (the membrane covering the white part of the eye) due to allergy. Although allergens differ among patients, the most common cause is hay fever. Symptoms consist ...

. It is produced by

Allergan Allergan plc is an American, Irish-domiciled pharmaceutical company that acquires, develops, manufactures and markets brand name drugs and medical devices in the areas of medical aesthetics, eye care, central nervous system, and gastroenterology. ...

and marketed by

Inspire Inspiration, inspire, INSPIRE, or inspired commonly refers to: * Artistic inspiration, sudden creativity in artistic production * Biblical inspiration, a Christian doctrine on the origin of the Bible * Inhalation, breathing in Inspiration and rel ...

in the United States. It is highly selective for the H₁ receptor and does not cross the blood-brain-barrier. It was patented in 1980 and came into medical use in 1994.

References

Azepanes H1 receptor antagonists Guanidines Drugs developed by AbbVie Mast cell stabilizers Peripherally selective drugs {{respiratory-system-drug-stub