Epidermal nevus syndrome, also known as Feuerstein and Mims syndrome,
and Solomon's syndrome
[Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in General Medicine''. (6th ed.). McGraw-Hill. .] is a
rare disease that was first described in 1968 and consists of extensive epidermal
nevi with abnormalities of the
central nervous system
The central nervous system (CNS) is the part of the nervous system consisting primarily of the brain, spinal cord and retina. The CNS is so named because the brain integrates the received information and coordinates and influences the activity o ...
(CNS), skeleton, skin,
cardiovascular system
In vertebrates, the circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the body. It includes the cardiovascular system, or vascular system, that consists of the heart a ...
,
genitourinary system and eyes.
[James, William; Berger, Timothy; Elston, Dirk (2005). ''Andrews' Diseases of the Skin: Clinical Dermatology''. (10th ed.). Saunders. .] However, since the syndrome's first description, a broader concept for the "epidermal nevus" syndrome has been proposed, with at least six types being described:
[Happle, R. "Epidermal nevus syndrome." ''Semin Dermatol''. 1995;14:111.]
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Schimmelpenning syndrome
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Nevus comedonicus syndrome
Nevus comedonicus syndrome is a skin condition characterized by a nevus comedonicus associated with cataracts, scoliosis
Scoliosis (: scolioses) is a condition in which a person's Vertebral column, spine has an irregular curve in the corona ...
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Pigmented hairy epidermal nevus syndrome
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Proteus syndrome
Proteus syndrome is a rare genetic disorder that can cause tissue overgrowth involving all three Germ layer, embryonic lineages. Patients with Proteus syndrome tend to have an increased risk of embryonic tumor development.Freedberg, et al. (2003). ...
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CHILD syndrome
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Phakomatosis pigmentokeratotica
See also
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Epidermis
The epidermis is the outermost of the three layers that comprise the skin, the inner layers being the dermis and Subcutaneous tissue, hypodermis. The epidermal layer provides a barrier to infection from environmental pathogens and regulates the ...
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List of cutaneous conditions
Many skin conditions affect the human integumentary system—the organ system covering the entire surface of the Human body, body and composed of Human skin, skin, hair, Nail (anatomy), nails, and related muscle and glands. The major function o ...
References
External links
Epidermal nevi, neoplasms, and cysts
Rare syndromes
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