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Ephraim McDowell (November 11, 1771 – June 25, 1830) was an American physician and pioneer surgeon. The first person to successfully remove an ovarian tumor, he has been called "the father of ovariotomy" as well as founding father of
abdominal surgery The term abdominal surgery broadly covers surgical procedures that involve opening the abdomen (laparotomy). Surgery of each abdominal organ is dealt with separately in connection with the description of that organ (see stomach, kidney, liver, e ...
.


Early life

McDowell was born in
Rockbridge County, Virginia Rockbridge County is a County (United States), county in the Shenandoah Valley on the western edge of the Commonwealth (U.S. state), Commonwealth of Virginia. As of the 2020 United States census, 2020 census, the population was 22,650. Its count ...
, the ninth child of
Samuel Samuel is a figure who, in the narratives of the Hebrew Bible, plays a key role in the transition from the biblical judges to the United Kingdom of Israel under Saul, and again in the monarchy's transition from Saul to David. He is venera ...
and Mary McDowell. His father was a veteran of the
French and Indian War The French and Indian War, 1754 to 1763, was a colonial conflict in North America between Kingdom of Great Britain, Great Britain and Kingdom of France, France, along with their respective Native Americans in the United States, Native American ...
and a colonel during the
American Revolution The American Revolution (1765–1783) was a colonial rebellion and war of independence in which the Thirteen Colonies broke from British America, British rule to form the United States of America. The revolution culminated in the American ...
. In 1784 Samuel McDowell was appointed land commissioner and moved his family to
Danville, Kentucky Danville is a list of Kentucky cities, home rule-class city and the county seat of Boyle County, Kentucky, United States. The population was 17,236 at the 2020 United States census, 2020 census. Danville is the principal city of the Danville Micr ...
. There, he presided over ten conventions that resulted in the drafting of the Kentucky Constitution. Samuel was the 2nd great-grandfather of First Lady
Mary Todd Lincoln Mary Ann Todd Lincoln (Birth name, née Todd; December 13, 1818July 16, 1882) was First Lady of the United States from 1861 until the assassination of her husband, President Abraham Lincoln, in 1865. Mary Todd was born into a large and wealthy ...
, making her Ephraim McDowell's great-grandniece.


Education

McDowell received his early education at the classical seminary of Worley and James, then spent three years as a medical student under Dr. Alexander Humphreys in
Staunton, Virginia Staunton ( ) is an independent city (United States), independent city in the Commonwealth (U.S. state), U.S. Commonwealth of Virginia. As of the 2020 United States census, 2020 census, the population was 25,750. In Virginia, independent cities a ...
. He attended lectures in medicine at the
University of Edinburgh The University of Edinburgh (, ; abbreviated as ''Edin.'' in Post-nominal letters, post-nominals) is a Public university, public research university based in Edinburgh, Scotland. Founded by the City of Edinburgh Council, town council under th ...
,
Scotland Scotland is a Countries of the United Kingdom, country that is part of the United Kingdom. It contains nearly one-third of the United Kingdom's land area, consisting of the northern part of the island of Great Britain and more than 790 adjac ...
, from 1793 to 1794 and studied privately with John Bell. He never received a diploma, but in 1825, the
University of Maryland The University of Maryland, College Park (University of Maryland, UMD, or simply Maryland) is a public land-grant research university in College Park, Maryland, United States. Founded in 1856, UMD is the flagship institution of the Univ ...
conferred on him an honorary M.D. degree.


Career

In 1795, McDowell returned from Scotland, settled in Danville, Kentucky, and began his practice as a surgeon. McDowell perfected the modern surgical technique of lithotomy, for removal of stones obstructing the urinary bladder. One of his most famous patients was James K. Polk, for whom he removed a urinary stone and repaired a
hernia A hernia (: hernias or herniae, from Latin, meaning 'rupture') is the abnormal exit of tissue or an organ (anatomy), organ, such as the bowel, through the wall of the cavity in which it normally resides. The term is also used for the normal Devel ...
.


First ovariotomy

On December 13, 1809, McDowell was called to see Jane Todd Crawford in Green County, Kentucky, from Danville. Her physicians thought that Mrs. Crawford was beyond term pregnant. McDowell diagnosed an ovarian tumor. Crawford begged him to keep her from a slow and painful death. He then described her condition and that an operation for cure had never been performed. He said that the best surgeons in the world thought it impossible. Crawford said she understood and wanted to proceed. McDowell told her he would remove the tumor if she would travel to his home in Danville. She agreed and rode the 60 miles on horseback. On Christmas morning, 1809, McDowell began his operation. The surgery was performed without benefit of anesthetic or antisepsis, neither of which was then known to the medical profession. The tumor McDowell removed weighed . He determined that it would be difficult to remove completely, so he tied a
ligature Ligature may refer to: Language * Ligature (writing), a combination of two or more letters into a single symbol (typography and calligraphy) * Ligature (grammar), a morpheme that links two words Medicine * Ligature (medicine), a piece of suture us ...
around the
fallopian tube The fallopian tubes, also known as uterine tubes, oviducts or salpinges (: salpinx), are paired tubular sex organs in the human female body that stretch from the Ovary, ovaries to the uterus. The fallopian tubes are part of the female reproduct ...
near the
uterus The uterus (from Latin ''uterus'', : uteri or uteruses) or womb () is the hollow organ, organ in the reproductive system of most female mammals, including humans, that accommodates the embryonic development, embryonic and prenatal development, f ...
and cut open the tumor. He described the tumor as the ovarium and fimbrious part of the fallopian tube very much enlarged. The whole procedure took 25 minutes. Crawford made an uncomplicated recovery. She returned to her home in Green County 25 days after the operation and lived another 32 years. This was the first successful removal of an ovarian tumor in the world. As a
Presbyterian Presbyterianism is a historically Reformed Protestant tradition named for its form of church government by representative assemblies of elders, known as "presbyters". Though other Reformed churches are structurally similar, the word ''Pr ...
,August Schachner. 1921.
Ephraim McDowell, "Father of Ovariotomy" and Founder of Abdominal Surgery
'. Ephraim McDowell, "Father of Ovariotomy" and Founder of Abdominal Surgery, p. 4; 58
McDowell's response to this event was recorded in one of his biographies:
How is it that I have been so peculiarly fortunate with my patients of this description?, I know not; for, from all the information I can obtain, there has not one individual survived who has been operated, on elsewhere, for diseased ovaria. I can only say that the blessing of God has rested on my efforts.
All attempts at abdominal exploration before 1809 had resulted in
peritonitis Peritonitis is inflammation of the localized or generalized peritoneum, the lining of the inner wall of the abdomen and covering of the abdominal organs. Symptoms may include severe pain, swelling of the abdomen, fever, or weight loss. One pa ...
and death. Descriptions of McDowell include phrases like "neat and clean" or "scrupulously clean." He was not only neat, but meticulous. In his report on the operation, he described the removal of blood from the peritoneal cavity and bathing the intestines with warm water. McDowell did not publish a description of his procedure until 1817, after he had performed two more such operations. This was widely criticized in the English surgical literature. There is evidence that he performed at least 12 operations for ovarian pathology. "Having never seen so large a substance extracted, nor heard of an attempt, or success attending any operation such as this required, I gave to the unhappy woman information of her dangerous situation. The tumor appeared full in view, but was so large we could not take it away entire. We took out fifteen pounds of a dirty, gelatinous looking substance. After which we cut through the fallopian tube, and extracted the sac, which weighed seven pounds and one half. In five days I visited her, and much to my astonishment found her making up her bed."


Later career

From 1809 and 1818, McDowell wrote about four separate ovariotomies following Crawford's. All four were performed on enslaved women, three of whom survived and one of whom died. It is unclear whether the enslaved women he performed surgeries on gave consent or received sufficient time to recover following the procedure.


Personal life

In 1802, McDowell married Sarah Shelby, daughter of war hero and two-time Kentucky governor
Isaac Shelby Isaac Shelby (December 11, 1750 – July 18, 1826) was an American politician and military officer who was the List of governors of Kentucky, first and fifth Governor of Kentucky and served in the state legislatures of Virginia and North Ca ...
. They had two sons and four daughters. He was a slaveholder. McDowell played a prominent role in his community. He was also a founder, original corporator, and member of the primary board of trustees of
Centre College Centre College, formally Centre College of Kentucky, is a Private college, private Liberal arts colleges in the United States, liberal arts college in Danville, Kentucky, United States. Chartered by the Kentucky General Assembly in 1819, the col ...
in Danville. McDowell became a member of the Philadelphia Medical Society in 1817. McDowell was the great-great-grandfather of General John Campbell Greenway, whose statue was placed in the National Statuary Hall Collection by the state of
Arizona Arizona is a U.S. state, state in the Southwestern United States, Southwestern region of the United States, sharing the Four Corners region of the western United States with Colorado, New Mexico, and Utah. It also borders Nevada to the nort ...
in 1930. He was cousin to woman's suffrage leader Madeline McDowell Breckinridge. McDowell was a Presbyterian but became an
Episcopalian Anglicanism, also known as Episcopalianism in some countries, is a Western Christian tradition which developed from the practices, liturgy, and identity of the Church of England following the English Reformation, in the context of the Protes ...
and founded Trinity Episcopal Church in Danville, Kentucky, having donated the land for its first building.


Death

In June 1830, McDowell was stricken with an acute attack of violent pain, nausea, and fever. He died on June 25, most likely a victim of
appendicitis Appendicitis is inflammation of the Appendix (anatomy), appendix. Symptoms commonly include right lower abdominal pain, nausea, vomiting, fever and anorexia (symptom), decreased appetite. However, approximately 40% of people do not have these t ...
. New International Encyclopedia His wife died 18 years later. They were buried at "Traveller's Rest", the homestead of Isaac Shelby, south of Danville, Kentucky but were reinterred in 1879, near a monument dedicated to him in Danville.


Honors

* In 1879, a monument in his honor was erected by the Medical Society of Kentucky in Danville. * In 1929, Isaac Wolfe Bernheim donated a bronze statue of McDowell by
Charles Henry Niehaus Charles Henry Niehaus (January 24, 1855 – June 19, 1935) was an American sculptor. Early life and education Niehaus was born in Cincinnati, Ohio, to German parents. He began working as a marble and wood carver, and then gained entrance to the ...
to the state of Kentucky for placement in the U.S. Capitol's
National Statuary Hall Collection The National Statuary Hall Collection in the United States Capitol is composed of statues donated by individual states to honor persons notable in their history. Limited to two statues per state, the collection was originally set up in the old Hal ...
. The statue depicts the ovarian tumor that McDowell removed from Jane Crawford, sitting in a bowl on the table behind McDowell. An identical statue by the same artist stands in the rotunda of the
Kentucky State Capitol The Kentucky State Capitol is located in Frankfort, Kentucky, Frankfort and is the house of the three branches (executive, legislative, judicial) of the Politics of the United States, state government of the Commonwealth (U.S. state), Commonwe ...
in
Frankfort, Kentucky Frankfort is the List of capitals in the United States, capital city of the U.S. state of Kentucky. It is a list of Kentucky cities, home rule-class city and the county seat, seat of Franklin County, Kentucky, Franklin County in the Upland Sou ...
. * In 1959, on December 3, the U.S. Post office first issued a 4-cent
commemorative stamp A commemorative stamp is a postage stamp, often issued on a significant date such as an anniversary, to honor or commemorate a place, event, person, or object. The ''subject'' of the commemorative stamp is usually spelled out in print, unlike defi ...
honoring McDowell, in the Danville, Kentucky, post office, marking the 150th anniversary of the first successful ovarian operation. * McDowell's house, office, and apothecary in Danville are preserved as a
museum A museum is an institution dedicated to displaying or Preservation (library and archive), preserving culturally or scientifically significant objects. Many museums have exhibitions of these objects on public display, and some have private colle ...
and are designated a
National Historic Landmark A National Historic Landmark (NHL) is a National Register of Historic Places property types, building, district, object, site, or structure that is officially recognized by the Federal government of the United States, United States government f ...
. * Ephraim McDowell Regional Medical Center in Danville is named in his honor.


References


Further reading

* * * Ridenbaugh, Mary Young.
The biography of Ephraim McDowell, M.D., "the father of ovariotomy.
'' (1890). New York, C.L. Webster {{DEFAULTSORT:McDowell, Ephraim 1771 births 1830 deaths Alumni of the University of Edinburgh American gynecologists Centre College people Converts to Anglicanism from Presbyterianism People from Danville, Kentucky People from Rockbridge County, Virginia 19th-century American Episcopalians 18th-century American physicians 18th-century surgeons 19th-century American surgeons American slave owners