Ent-kaurenoic acid oxidase () is an
enzyme
An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different mol ...
with
systematic name
A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature.
A semisystematic name or semitrivi ...
''ent-kaur-16-en-19-oate,NADPH:oxygen oxidoreductase (hydroxylating)''.
This enzyme
catalyses the following
chemical reaction
A chemical reaction is a process that leads to the chemistry, chemical transformation of one set of chemical substances to another. When chemical reactions occur, the atoms are rearranged and the reaction is accompanied by an Gibbs free energy, ...
: ent-kaur-16-en-19-oate + 3 NADPH + 3 H
+ + 3 O
2 gibberellin A12 + 3 NADP
+ + 4 H
2O (overall reaction)
:(1a) ent-kaur-16-en-19-oate + NADPH + H
+ + O
2 ent-7alpha-hydroxykaur-16-en-19-oate + NADP
+ + H
2O
:(1b) ent-7alpha-hydroxykaur-16-en-19-oate + NADPH + H
+ + O
2 gibberellin A12 aldehyde + NADP
+ + 2 H
2O
:(1c) gibberellin A12 aldehyde + NADPH + H
+ + O
2 gibberellin A12 + NADP
+ + H
2O
Ent-kaurenoic acid oxidase requires
cytochrome P450
Cytochromes P450 (P450s or CYPs) are a Protein superfamily, superfamily of enzymes containing heme as a cofactor (biochemistry), cofactor that mostly, but not exclusively, function as monooxygenases. However, they are not omnipresent; for examp ...
.
References
External links
*
EC 1.14.13
{{Enzyme-stub