Encaprin
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Encaprin was a brand of safety-coated
aspirin Aspirin () is the genericized trademark for acetylsalicylic acid (ASA), a nonsteroidal anti-inflammatory drug (NSAID) used to reduce pain, fever, and inflammation, and as an antithrombotic. Specific inflammatory conditions that aspirin is ...
capsules made by
Procter & Gamble The Procter & Gamble Company (P&G) is an American multinational consumer goods corporation headquartered in Cincinnati, Ohio. It was founded in 1837 by William Procter and James Gamble. It specializes in a wide range of personal health/con ...
in the mid-1980s through its Norwich Eaton Pharmaceuticals division. In 1986, the brand was involved in a
cyanide In chemistry, cyanide () is an inorganic chemical compound that contains a functional group. This group, known as the cyano group, consists of a carbon atom triple-bonded to a nitrogen atom. Ionic cyanides contain the cyanide anion . This a ...
poisoning hoax, and its sales never recovered.


History

Procter & Gamble submitted a
patent application A patent application is a request pending at a patent office for the grant of a patent for an invention described in the patent specification and a set of one or more claim (patent), claims stated in a formal document, including necessary officia ...
on 14 March 1983 for its new line of
over-the-counter Over-the-counter (OTC) drugs are medicines sold directly to a consumer without a requirement for a prescription from a healthcare professional, as opposed to prescription drugs, which may be supplied only to consumers possessing a valid pres ...
micro-granulated aspirin capsules, to be sold under the name Encaprin, chosen for its phonetic similarity to the word aspirin. The product was first released in January 1984 to a lead market in
Tucson, Arizona Tucson (; ; ) is a city in Pima County, Arizona, United States, and its county seat. It is the second-most populous city in Arizona, behind Phoenix, Arizona, Phoenix, with a population of 542,630 in the 2020 United States census. The Tucson ...
, and saw its national release in early May. A national television advertising campaign began on July 15, 1984, where it was marketed as a fast-acting
analgesic An analgesic drug, also called simply an analgesic, antalgic, pain reliever, or painkiller, is any member of the group of drugs used for pain management. Analgesics are conceptually distinct from anesthetics, which temporarily reduce, and in s ...
, particularly for mild
arthritis Arthritis is a general medical term used to describe a disorder that affects joints. Symptoms generally include joint pain and stiffness. Other symptoms may include redness, warmth, Joint effusion, swelling, and decreased range of motion of ...
relief, while being easier on the stomach than traditional or buffered aspirin tablets, due to its distributed aspirin micro-granules. The brand saw problems early on when a
trademark infringement Trademark infringement is a violation of the exclusive rights attached to a trademark without the authorization of the trademark owner or any licensees (provided that such authorization was within the scope of the licence). Infringement may occ ...
suit was filed by
SmithKline Beckman Smith, Kline & French (SKF) was an American pharmaceutical company that is now a part of the British group GSK plc. History In 1830, John K. Smith opened a drugstore in Philadelphia, and his younger brother, George, joined him in 1841 to form ...
, the makers of Ecotrin, a solid safety-coated aspirin tablet. The ruling sided with Procter & Gamble, and they were allowed to keep the Encaprin name. Success for Encaprin was short-lived, however, as the product faced intense competition from the
acetaminophen Paracetamol, or acetaminophen, is a non-opioid analgesic and antipyretic agent used to treat fever and mild to moderate pain. It is a widely available over-the-counter drug sold under various brand names, including Tylenol and Panadol. Parac ...
-containing
Tylenol Tylenol may refer to: * Paracetamol (acetaminophen), a medication used to treat pain and fever * Tylenol (brand), an American brand of drugs containing paracetamol * Chicago Tylenol murders The Chicago Tylenol murders were a series of poisoning d ...
and other aspirin products. Encaprin's roll-out was further hampered by its timing. The product came onto the national market in May 1984, the same month
ibuprofen Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain, fever, and inflammation. This includes dysmenorrhea, painful menstrual periods, migraines, and rheumatoid arthritis. It can be taken oral administration, ...
was approved for
over-the-counter Over-the-counter (OTC) drugs are medicines sold directly to a consumer without a requirement for a prescription from a healthcare professional, as opposed to prescription drugs, which may be supplied only to consumers possessing a valid pres ...
sale.
Advil Advil is a brand of pain reliever, pain-relieving medication, currently owned by Haleon, Haleon plc. The primary active ingredient in most Advil-branded products is ibuprofen, a non-steroidal anti-inflammatory drug, nonsteroidal anti-inflammato ...
, marketed by SKB, along with
Bristol Myers The Bristol-Myers Squibb Company, doing business as Bristol Myers Squibb (BMS), is an American multinational pharmaceutical company. Headquartered in Princeton, New Jersey, BMS is one of the world's largest pharmaceutical companies and consiste ...
's Nuprin, promptly came to market, benefiting from ibuprofen's successful ten-year track record. Advil quickly became a blockbuster perennial brand and
genericized trademark A generic trademark, also known as a genericized trademark or proprietary eponym, is a trademark or brand name that, because of its popularity or significance, has become the generic term for, or synonymous with, a general class of products or ...
itself for ibuprofen. Despite heavy marketing, consumers saw no real benefit in Encaprin. Commodity drugs such as aspirin were (and are) available at lower cost for higher quantity in their original form, usually tablets. Encaprin was seen as merely a way to give aspirin an unjustified markup. P&G chose to focus more on the drug's coating being easier to stomach rather than the pure
efficacy Efficacy is the ability to perform a task to a satisfactory or expected degree. The word comes from the same roots as '' effectiveness'', and it has often been used synonymously, although in pharmacology a distinction is now often made betwee ...
of pain relief their competitors emphasized. In addition to the competition from acetaminophen and ibuprofen, the regular and buffered aspirin brands of the time (including market leader
Sterling Drug Sterling Drug was an American based global pharmaceutical company. It was also known as Sterling Winthrop, Inc., after the merger with Winthrop-Stearns Inc. which itself resulted from the merger of Winthrop Chemical Company Inc. and Frederick Ste ...
's Bayer Aspirin) then offered new higher-dose forms of aspirin which provided pain relief, lower stomach discomfort, and lower prices. Or competitors discounted their products to easily fend off P&G's challenge. Encaprin was soon embroiled in the
product tampering Tampering can refer to many forms of sabotage but the term is often used to mean intentional modification of products in a way that would make them harmful to the consumer. This threat has prompted manufacturers to make products that are either d ...
scares following the 1982
Chicago Tylenol murders The Chicago Tylenol murders were a series of poisoning deaths resulting from drug tampering in the Chicago metropolitan area in 1982. The victims consumed Tylenol-branded acetaminophen (paracetamol) capsules that had been laced with potassium ...
. On March 27, 1986, an anonymous caller phoned P&G's
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customer support Customer support is a range of services to assist customers in making cost effective and correct use of a product. It includes assistance in planning, installation, training, troubleshooting, maintenance, upgrading, and disposal of a product. Rega ...
line, claiming he had placed
cyanide In chemistry, cyanide () is an inorganic chemical compound that contains a functional group. This group, known as the cyano group, consists of a carbon atom triple-bonded to a nitrogen atom. Ionic cyanides contain the cyanide anion . This a ...
in capsules of maximum strength Encaprin in
Walgreens Walgreens is an American pharmacy store chain. It is the second largest in the United States, behind CVS Pharmacy. As of March 2025, the company operated more than 8,700 stores in the U.S. Walgreens has been the subject of a number of lawsuit ...
pharmacies in Chicago and Detroit, leading Walgreens,
Kroger The Kroger Company, or simply Kroger, is an American retail company that operates (either directly or through its subsidiaries) supermarkets and multi-department stores throughout the United States. Founded by Bernard Kroger in 1883 in Cinc ...
supermarkets and SupeRx drug stores to remove the product from all stores nationally. Despite there not being any Walgreens stores in
Metro Detroit Metro Detroit is a major metropolitan area in the U.S. state of Michigan, consisting of the city of Detroit and over 200 municipalities in the Southeast Michigan, surrounding area. There are varied definitions of the area, including the officia ...
in 1986 and the caller providing a non-existent
lot number A lot number is an identification number assigned to a particular quantity or lot of material from a single manufacturer. Lot numbers can typically be found on the outside of packaging. For cars, a lot number is combined with a serial number to fo ...
for the tampered medication, Norwich Eaton issued a recall and advisory cautions were announced. On April 5, 1986, Norwich Eaton and P&G announced that no evidence of tampering had been found, and Encaprin was returned to the shelves. Despite assurances Encaprin was never tampered with, the brand never recovered its sales, and P&G quietly retired it from sale in August 1986. The Encaprin hoax influenced the 1989 FDA federal guidelines for the manufacture of
tamper-proof Tamperproofing is a methodology used to hinder, deter or detect unauthorised access to a device or circumvention of a security system. Since any device or system can be foiled by a person with sufficient knowledge, equipment, and time, the term " ...
products, which called for a minimum of two layers of tamper-proof packaging for two-piece capsule products, and the use of tamper-proof capsule sealing technologies.


References

{{Portal, 1980s Former Procter & Gamble brands Defunct brands Hoaxes in the United States 1986 hoaxes Product recalls