Emily Bernstein is a professor at
Mount Sinai School of Medicine
The Icahn School of Medicine at Mount Sinai (ISMMS or Mount Sinai), formerly the Mount Sinai School of Medicine, is a private medical school in New York City. It is the academic teaching arm of the Mount Sinai Health System, which manages eig ...
known for her research on
RNA interference
RNA interference (RNAi) is a biological process in which RNA molecules are involved in sequence-specific suppression of gene expression by double-stranded RNA, through translational or transcriptional repression. Historically, RNAi was known by o ...
,
epigenetics
In biology, epigenetics is the study of stable phenotypic changes (known as ''marks'') that do not involve alterations in the DNA sequence. The Greek prefix '' epi-'' ( "over, outside of, around") in ''epigenetics'' implies features that are " ...
, and cancer, especially
melanoma.
Education and career
Bernstein received her B.S. from McGill University in 1998 and earned a Ph.D. from
Stony Brook University
Stony Brook University (SBU), officially the State University of New York at Stony Brook, is a public research university in Stony Brook, New York. Along with the University at Buffalo, it is one of the State University of New York syste ...
in 2003. Following her Ph.D. she was a postdoctoral researcher at
Rockefeller University
The Rockefeller University is a Private university, private Medical research, biomedical Research university, research and graduate-only university in New York City, New York (state), New York. It focuses primarily on the biological and medica ...
where she worked with David Altis. In 2008 she moved to Mount Sinai School of Medicine where, as of 2022, she is a professor in the department of oncology and dermatology.
Research
Bernstein is known for her research on RNA interference, epigenetics, and cell development. Her early research examined the enzyme
Dicer
Dicer, also known as endoribonuclease Dicer or helicase with RNase motif, is an enzyme that in humans is encoded by the gene. Being part of the RNase III family, Dicer cleaves double-stranded RNA (dsRNA) and pre-microRNA (pre-miRNA) into short ...
, its role in cell development in mice, and
RNA interference
RNA interference (RNAi) is a biological process in which RNA molecules are involved in sequence-specific suppression of gene expression by double-stranded RNA, through translational or transcriptional repression. Historically, RNAi was known by o ...
. While a postdoctoral researcher she examined linkages between non-coding RNA and chromatin and
DNA methylation
DNA methylation is a biological process by which methyl groups are added to the DNA molecule. Methylation can change the activity of a DNA segment without changing the sequence. When located in a gene promoter, DNA methylation typically acts ...
. Subsequently, she has worked on histones, gene silencing, and tumor cell development. In 2022 her team discovered alterations to a gene which can lead to melanoma.
Selected publications
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Awards and honors
In 2014 Bernstein received a young investigators award from the
Pershing Square Foundation.
References
External links
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* , May 14, 2016
{{DEFAULTSORT:Bernstein, Emily
Living people
McGill University alumni
Stony Brook University alumni
Icahn School of Medicine at Mount Sinai faculty
Women medical researchers
Cancer researchers
Year of birth missing (living people)