
Emanuel Edward Klein
FRS (31 October 1844 at
Osijek
Osijek () is the fourth-largest city in Croatia, with a population of 96,848 in 2021. It is the largest city and the economic and cultural centre of the eastern Croatian region of Slavonia, as well as the administrative centre of Osijek-Baranja ...
– 9 February 1925 at
Hove
Hove is a seaside resort and one of the two main parts of the city of Brighton and Hove, along with Brighton in East Sussex, England. Originally a "small but ancient fishing village" surrounded by open farmland, it grew rapidly in the 19th ce ...
) was a
bacteriologist
A bacteriologist is a microbiologist, or similarly trained professional, in bacteriology -- a subdivision of microbiology that studies bacteria, typically pathogenic ones. Bacteriologists are interested in studying and learning about bacteria, as ...
who was born in
Croatia
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and educated in
Austria
Austria, , bar, Östareich officially the Republic of Austria, is a country in the southern part of Central Europe, lying in the Eastern Alps. It is a federation of nine states, one of which is the capital, Vienna, the most populous ...
before settling in Britain. He is sometimes known as the father of British
microbiology
Microbiology () is the scientific study of microorganisms, those being unicellular (single cell), multicellular (cell colony), or acellular (lacking cells). Microbiology encompasses numerous sub-disciplines including virology, bacteriology, ...
, but most of his work in microbiology, histology, and bacteriology was overshadowed during his life by his use of and apparently outspoken support for animal
vivisection
Vivisection () is surgery conducted for experimental purposes on a living organism, typically animals with a central nervous system, to view living internal structure. The word is, more broadly, used as a pejorative catch-all term for experimen ...
in
physiological
Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemica ...
and medical experiments. His English was poor and during court questioning, many of the answers he provided were considered shocking.
Life and work

Klein was born on 31 October 1844 at
Osijek
Osijek () is the fourth-largest city in Croatia, with a population of 96,848 in 2021. It is the largest city and the economic and cultural centre of the eastern Croatian region of Slavonia, as well as the administrative centre of Osijek-Baranja ...
in a German speaking non-practicing
Jewish
Jews ( he, יְהוּדִים, , ) or Jewish people are an ethnoreligious group and nation originating from the Israelites Israelite origins and kingdom: "The first act in the long drama of Jewish history is the age of the Israelites""The ...
home. His father, who died when he was about fourteen, was a tanner working for a Russian leather company. After graduating in the local school he became a tutor in the classics and at eighteen he worked in London to help his family. He later went to study medicine at
Vienna
en, Viennese
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and obtained an M.D. in 1869. At Vienna he worked with
Ernst Wilhelm Brücke
Ernst is both a surname and a given name, the German, Dutch, and Scandinavian form of Ernest. Notable people with the name include:
Surname
* Adolf Ernst (1832–1899) German botanist known by the author abbreviation "Ernst"
* Anton Ernst (1975 ...
''.'' In 1871 he visited England to help in the translation of a German work
Handbuch der Lehre von den Geweben des Menschen und der Thiere' by his Viennese teachers
Salomon Stricker (1834-1898). The hosts,
John Burdon Sanderson and John Simon were impressed by his knowledge and they invited Klein to work in London in 1871. Klein moved to the
Brown Animal Sanatory Institution and in 1873, became a professor of comparative pathology. He also worked at
Saint Bartholomew's Hospital where he was made a joint professor of general anatomy and physiology.
His work on animal physiology was published in ''Handbook for the Physiological Laboratory'' in 1873, along with Burdon Sanderson,
Thomas Lauder Brunton
Sir Thomas Lauder Brunton, 1st Baronet, (14 March 1844 – 16 September 1916) was a British physician who is most-closely associated with the use of amyl nitrite to treat angina pectoris.
Early life
Brunton was born on 14 March 1844 in Roxburgh ...
and
Michael Foster and they made use of experimental methods on living animals, something that were considered acceptable in the Vienna Medical School. The anti-vivisection movement protested the methods described in their textbook and in 1875, after he was elected
Fellow of the Royal Society
Fellowship of the Royal Society (FRS, ForMemRS and HonFRS) is an award granted by the judges of the Royal Society of London to individuals who have made a "substantial contribution to the improvement of natural knowledge, including mathematic ...
, the Royal Commission on Vivisection for Scientific Purposes held its hearings and although Foster, Brunton and Burdon Sanderson were careful in responding to the queries, Klein responded without any apparent remorse although some biographers attribute it to his limited knowledge of English. Klein tried to provide a revised text of his responses but the Royal Commission rejected this. Klein was made into a monster by the media, and he became the main target of the anti-vivisectionists and the case led to the establishment of the
Cruelty to Animals Act 1876.
Klein worked at the Brown Institution from 1871 to 1897 during which time he also mentored students that included Francis Darwin, Jeremiah MacCarthy, James Adams and Frederick Treves.
The media coverage during the anti-vivisection case made Klein widely infamous. Several novels of the period were inspired by the case including ''Paul Faber, Surgeon'' (1878) by George MacDonald; ''The Professor's Wife'' (1881) by Leonard Graham and ''Heart and Science'' (1883) by
Wilkie Collins
William Wilkie Collins (8 January 1824 – 23 September 1889) was an English novelist and playwright known especially for '' The Woman in White'' (1859), a mystery novel and early "sensation novel", and for ''The Moonstone'' (1868), which has be ...
. These novels included a scientist as a key character, modelled after Klein and juxtaposed with a range of negative traits and ethnic stereotypes.
Klein's training in Europe however allowed him to access the microbiological techniques developed by
Louis Pasteur
Louis Pasteur (, ; 27 December 1822 – 28 September 1895) was a French chemist and microbiologist renowned for his discoveries of the principles of vaccination, microbial fermentation and pasteurization, the latter of which was named after ...
and
Robert Koch, and he wrote the first major English work in bacteriology in 1884. In 1884, Klein,
Alfred Lingard
Alfred Lingard (1849 – 18 February 1938) was a British medical pathologist who worked on veterinary diseases in India, serving as an Imperial Bacteriologist from 1890 to 1907. He was the founding director of the Imperial Bacteriological Laborato ...
, and
Heneage Gibbes
Heneage Gibbes (1837 – July 18, 1912) was a British pathologist known for his histological studies. He moved to the United States where he served as a professor of pathology at the University of Michigan, Ann Arbor.
Gibbes was born in Berrow, ...
were sent as part of the British cholera commission to Calcutta in India to verify the findings of Koch which had caused some embarrassment to the British Indian medical community. Klein was able to find the comma-shaped ''
Vibrio cholerae
''Vibrio cholerae'' is a species of Gram-negative, facultative anaerobe and comma-shaped bacteria. The bacteria naturally live in brackish or saltwater where they attach themselves easily to the chitin-containing shells of crabs, shrimps, and ot ...
'' bacteria in the water supply where Koch had found them as well as in the stools of infected patients. He however did not fully accept the idea that the same bacteria caused the disease.
In 1885, he studied the outbreak of a disease of cows which was termed as
scarlet fever
Scarlet fever, also known as Scarlatina, is an infectious disease caused by ''Streptococcus pyogenes'' a Group A streptococcus (GAS). The infection is a type of Group A streptococcal infection (Group A strep). It most commonly affects child ...
and isolated four species of bacteria during the research, including ''
Streptococcus pyogenes
''Streptococcus pyogenes'' is a species of Gram-positive, aerotolerant bacteria in the genus '' Streptococcus''. These bacteria are extracellular, and made up of non-motile and non-sporing cocci (round cells) that tend to link in chains. They ...
'', the causal agent. Klein also worked on bacteria in food and helped in establishing methods for food processing and preservation. Of the 264 scientific publications in his career nearly 200 were in microbiology.
Ronald Ross
Sir Ronald Ross (13 May 1857 – 16 September 1932) was a British medical doctor who received the Nobel Prize for Physiology or Medicine in 1902 for his work on the transmission of malaria, becoming the first British Nobel laureate, and the ...
was one of Klein's students. Klein was the author of the ''Elements of Histology'' (1883).
His name was originally just Emanuel and he signed as E.Klein but during his membership with the Organon Club (founded by Ray Lankester) the secretary thought it stood for Edward. Klein was a founding member of the Medical Research Club (1891) and was a joint editor of the ''Quarterly Journal of Microscopical Science''.
Personal life
He married Sophia Mawley (died 1919) in 1877.
They had a son, Bernard and two daughters. Klein was an able chess player and a musician.
He died of pneumonia at his home in
Hove
Hove is a seaside resort and one of the two main parts of the city of Brighton and Hove, along with Brighton in East Sussex, England. Originally a "small but ancient fishing village" surrounded by open farmland, it grew rapidly in the 19th ce ...
on 9 February 1925.
References
External links
The anatomy of the lymphatic system (1873)* Elements of Histolog
18831895
Micro-organisms and Disease (1886)
Handbook for the physiological laboratory
(1873, with Burdon-Sanderson, Michael Foster, and T.L. Brunton)
The bacteria in Asiatic cholera (1889)
The etiology and pathology of grouse disease, fowl enteritis, and some other diseases affecting birds (1892)
Studies in the bacteriology & etiology of oriental plague (1906)
{{DEFAULTSORT:Klein, Emanuel Edward
1844 births
1925 deaths
British Jews
British pathologists
Jewish scientists
Fellows of the Royal Society