Eggerthellales
   HOME

TheInfoList



OR:

The Eggerthellaceae are a family of
Gram-positive In bacteriology, gram-positive bacteria are bacteria that give a positive result in the Gram stain test, which is traditionally used to quickly classify bacteria into two broad categories according to their type of cell wall. The Gram stain is ...
, rod- or coccus-shaped
Actinomycetota The Actinomycetota (or Actinobacteria) are a diverse phylum of Gram-positive bacteria with high GC content. They can be terrestrial or aquatic. They are of great importance to land flora because of their contributions to soil systems. In soil t ...
. It is the sole family within the order ''Eggerthellales.'' The name ''Eggerthellaceae'' is derived from the Latin term '' Eggerthella,'' referring to the type genus of the family and the suffix "-ceae," an ending used to denote a family. Together, ''Eggerthellaceae'' refers to a family whose nomenclatural type is the genus '' Eggerthella''.


Biochemical characteristics and molecular signatures

Members of this family are mostly anaerobic, non-motile (with the exception of some ''Gordonibacter'' and ''Senegalimassilia'' species that exhibit motility), asaccharolytic and do not form spores. ''Eggerthellaceae'' species are commonly isolated from human and animal faeces and other human sources such as the colon, vagina, oral cavity and blood. Some species have also been isolated from human samples of periodontal or endodontic infections, Crohn's disease and severe blood bacteremia. The G+C content for ''Eggerthellaceae'' species is between 43.4 and 66.3 mol%. Analysis of genome sequences identified 13
conserved signature indels Conserved signature inserts and deletions (CSIs) in protein sequences provide an important category of molecular markers for understanding phylogenetic relationships. CSIs, brought about by rare genetic changes, provide useful phylogenetic markers ...
(CSIs) in diverse proteins that are exclusively present in different ''Eggerthellaceae'' species. The proteins containing these CSIs are: contaexcinuclease ABC subunit UvrC,
DNA polymerase III DNA polymerase III holoenzyme is the primary enzyme complex involved in prokaryotic DNA replication. It was discovered by Thomas Kornberg (son of Arthur Kornberg) and Malcolm Gefter in 1970. The complex has high processivity (i.e. the number o ...
subunit alpha,
ribonuclease III Ribonuclease III (RNase III or RNase C) (BREND3.1.26.3 is a type of ribonuclease that recognizes dsRNA and cleaves it at specific targeted locations to transform them into mature RNAs. These enzymes are a group of endoribonucleases that are char ...
, tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase (MiaB), peptide chain release factor 2, 16S rRNA (cytosine(1402)-N(4))-methyltransferase, elongation factor Tu, UDP-N-acetylglucosamine 1-carboxyvinyltransferase
DNA polymerase III DNA polymerase III holoenzyme is the primary enzyme complex involved in prokaryotic DNA replication. It was discovered by Thomas Kornberg (son of Arthur Kornberg) and Malcolm Gefter in 1970. The complex has high processivity (i.e. the number o ...
subunit epsilon,
UDP-glucose 4-epimerase The enzyme UDP-glucose 4-epimerase (), also known as UDP-galactose 4-epimerase or GALE, is a homodimeric epimerase found in bacterial, fungal, plant, and mammalian cells. This enzyme performs the final step in the Leloir pathway of galactose ...
and
DNA-directed RNA polymerase In biochemistry, a polymerase is an enzyme ( EC 2.7.7.6/7/19/48/49) that synthesizes long chains of polymers or nucleic acids. DNA polymerase and RNA polymerase are used to assemble DNA and RNA molecules, respectively, by copying a DNA template s ...
subunit alpha. The identified CSIs provide reliable and important means to distinguish members of ''Eggerthellaceae'' from all other Coriobacteriia as well as other bacteria.


Phylogeny

The currently accepted taxonomy is based on the
List of Prokaryotic names with Standing in Nomenclature List of Prokaryotic names with Standing in Nomenclature (LPSN) is an online database that maintains information on the naming and taxonomy of prokaryotes, following the taxonomy requirements and rulings of the International Code of Nomenclatu ...
(LPSN) and
National Center for Biotechnology Information The National Center for Biotechnology Information (NCBI) is part of the National Library of Medicine (NLM), a branch of the National Institutes of Health (NIH). It is approved and funded by the government of the United States. The NCBI is lo ...
(NCBI).


Notes


See also

*
List of bacteria genera This article lists the genera of the bacteria Bacteria (; : bacterium) are ubiquitous, mostly free-living organisms often consisting of one Cell (biology), biological cell. They constitute a large domain (biology), domain of Prokaryote, ...
*
List of bacterial orders This article lists the orders of the Bacteria. The currently accepted taxonomy is based on the List of Prokaryotic names with Standing in Nomenclature (LPSN) and National Center for Biotechnology Information (NCBI) and the phylogeny is based on 16 ...


References

Actinomycetota {{actinobacteria-stub