Efinopegdutide (MK-6024) is a dual agonist of the

glucagon Glucagon is a peptide hormone, produced by alpha cells of the pancreas. It raises the concentration of glucose and fatty acids in the bloodstream and is considered to be the main catabolic hormone of the body. It is also used as a Glucagon (medic ...

and GLP-1 receptors. It is being developed by Merck for

non-alcoholic fatty liver disease An alcohol-free or non-alcoholic drink, also known as a temperance drink, is a version of an alcoholic drink made without alcohol, or with the alcohol removed or reduced to almost zero. These may take the form of a non-alcoholic mixed drink or n ...

. It was also developed for type 2 diabetes and obesity but these indications were discontinued.

References

Glucagon receptor agonists GLP-1 receptor agonists Peptide therapeutics Drugs developed by Merck & Co. {{pharma-stub