Edwin Bennett Astwood (December 19, 1909 – February 17, 1976) was a Bermudian

physiologist Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a subdiscipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out chemical and ...

and

endocrinologist Endocrinology (from ''endocrine'' + '' -ology'') is a branch of biology and medicine dealing with the endocrine system, its diseases, and its specific secretions known as hormones. It is also concerned with the integration of developmental events ...

: his research on

endocrine system The endocrine system is a messenger system in an organism comprising feedback loops of hormones that are released by internal glands directly into the circulatory system and that target and regulate distant Organ (biology), organs. In vertebrat ...

led to treatments for

hyperthyroidism Hyperthyroidism is a endocrine disease in which the thyroid gland produces excessive amounts of thyroid hormones. Thyrotoxicosis is a condition that occurs due to elevated levels of thyroid hormones of any cause and therefore includes hyperth ...

, first published in 1943 in what has subsequently been called a "landmark" paper. In 1949 he showed that

methimazole Thiamazole, also known as methimazole, is a medication used to treat hyperthyroidism. This includes Graves' disease, toxic multinodular goiter, and thyrotoxic crisis. It is taken by mouth. Full effects may take a few weeks to occur. Commo ...

was superior to alternative therapies for

Graves' disease Graves' disease, also known as toxic diffuse goiter or Basedow's disease, is an autoimmune disease that affects the thyroid. It frequently results in and is the most common cause of hyperthyroidism. It also often results in an enlarged thyro ...

and this became a standard treatment for the condition. He was elected a Fellow of the

American Academy of Arts and Sciences The American Academy of Arts and Sciences (The Academy) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and other ...

in 1949. In 1948, he was awarded the

Cameron Prize for Therapeutics of the University of Edinburgh The Cameron Prize for Therapeutics of the University of Edinburgh is awarded by the University of Edinburgh College of Medicine and Veterinary Medicine, College of Medicine and Veterinary Medicine to a person who has made any highly important and v ...

. He died of cancer on February 17, 1976, in

Hamilton, Bermuda Hamilton is the capital city of the British Overseas Territory of Bermuda, and the main settlement of Pembroke Parish. A port city, Hamilton is Bermuda's financial and commercial centre, and a popular tourist destination. Its population of ...

References

*Cooper, D. Y. Astwood, Edwin Bennett. ''American National Biography Online'' Feb. 2000.

External links

National Academy of Sciences Biographical Memoir
1909 births 1976 deaths American physiologists American endocrinologists Recipients of the Albert Lasker Award for Basic Medical Research Fellows of the American Academy of Arts and Sciences 20th-century American physicians Deaths from cancer in Bermuda Bermudian emigrants to the United States {{US-physician-stub