Edward G. D. Tuddenham is a British

haematologist Hematology ( spelled haematology in British English) is the branch of medicine concerned with the study of the cause, prognosis, treatment, and prevention of diseases related to blood. It involves treating diseases that affect the production ...

who has authored over 200 papers in the field. He gained his

Bachelor of Medicine, Bachelor of Surgery A Bachelor of Medicine, Bachelor of Surgery (; MBBS, also abbreviated as BM BS, MB ChB, MB BCh, or MB BChir) is a medical degree granted by medical schools or universities in countries that adhere to the United Kingdom's higher education trad ...

at the

University of London The University of London (UoL; abbreviated as Lond or more rarely Londin in Post-nominal letters, post-nominals) is a collegiate university, federal Public university, public research university located in London, England, United Kingdom. The ...

in 1968 and his

Membership of the Royal College of Physicians Membership of the Royal Colleges of Physicians of the United Kingdom (MRCP(UK)) is a postgraduate medical diploma in the United Kingdom (UK). The examinations are run by the Federation of the Medical Royal Colleges – the Royal College of Phys ...

in 1975. Up until 2005 was head of the Haemostasis and Thrombosis Research ( Medical Research Council) Group at

Imperial College Imperial College London, also known as Imperial, is a public research university in London, England. Its history began with Prince Albert, husband of Queen Victoria, who envisioned a cultural district in South Kensington that included museums ...

. Professor Tuddenham is a pioneer in the field of

haemophilia Haemophilia (British English), or hemophilia (American English) (), is a mostly inherited genetic disorder that impairs the body's ability to make blood clots, a process needed to stop bleeding. This results in people bleeding for a long ...

and was responsible, along with Frances Rotblat, for the purification and cloning of the

factor VIII Coagulation factor VIII (Factor VIII, FVIII, also known as anti-hemophilic factor (AHF)) is an essential blood clotting protein. In humans, it is encoded by ''F8'' gene. Defects in this gene result in hemophilia A, an X-linked bleeding disorder ...

gene, which led to the highly effective and safe treatments available to haemophilia sufferers today. In more recent years, he has been actively involved in developing

gene therapy Gene therapy is Health technology, medical technology that aims to produce a therapeutic effect through the manipulation of gene expression or through altering the biological properties of living cells. The first attempt at modifying human DNA ...

for haemophilia. The first successful use of gene transfer to convert severe to mild haemophilia B was reported by his group in December 2011.He retired from Directorship of the Katharine Dormandy Centre in July 2011 and is now Emeritus Professor of Haemophilia at

University College London University College London (Trade name, branded as UCL) is a Public university, public research university in London, England. It is a Member institutions of the University of London, member institution of the Federal university, federal Uni ...

. He continues to work in the Haemophilia Centre at the

Royal Free Hospital The Royal Free Hospital (also known as the Royal Free) is a major teaching hospital in the Hampstead area of the London Borough of Camden. The hospital is part of the Royal Free London NHS Foundation Trust, which also runs services at Barnet Ho ...

on gene therapy clinical trials, with the goal of curing all forms of haemophilia.

References

* * * * * * {{DEFAULTSORT:Tuddenham, Edward British haematologists Living people 1944 births Fellows of the Academy of Medical Sciences (United Kingdom) Academics of University College London Physicians of the Royal Free Hospital Academics of Imperial College London