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Edmond Isidore Étienne Nocard (; 29 January 1850 – 2 August 1903), was a French
veterinarian A veterinarian (vet) or veterinary surgeon is a medical professional who practices veterinary medicine. They manage a wide range of health conditions and injuries in non-human animals. Along with this, veterinarians also play a role in animal r ...
and
microbiologist A microbiologist (from Greek ) is a scientist who studies microscopic life forms and processes. This includes study of the growth, interactions and characteristics of microscopic organisms such as bacteria, algae, fungi, and some types of par ...
, born in
Provins Provins () is a Communes of France, commune in the Seine-et-Marne Departments of France, department in the ÃŽle-de-France Regions of France, region in north-central France. Known for its well-preserved medieval architecture and importance througho ...
(
Seine-et-Marne Seine-et-Marne () is a department in the ÃŽle-de-France region in Northern France. Named after the rivers Seine and Marne, it is the region's largest department with an area of 5,915 square kilometres (2,284 square miles); it roughly covers its ...
,
France France, officially the French Republic, is a country located primarily in Western Europe. Overseas France, Its overseas regions and territories include French Guiana in South America, Saint Pierre and Miquelon in the Atlantic Ocean#North Atlan ...
). Nocard studied
veterinary medicine Veterinary medicine is the branch of medicine that deals with the prevention, management, medical diagnosis, diagnosis, and treatment of disease, disorder, and injury in non-human animals. The scope of veterinary medicine is wide, covering all a ...
from 1868 to 1871 and (after a brief service in the Army) from 1871 to 1873 in the
École Vétérinaire de Maisons-Alfort École or Ecole may refer to: * an elementary school in the French educational stages normally followed by secondary education establishments (collège and lycée) * École (river), a tributary of the Seine flowing in région Île-de-France * Éco ...
. From 1873 to 1878 he was hired as Head of Clinical Service at the same school, working with Dumesnil. In 1876 he is charged with the creation of a new journal, the ''Archives Vétérinaires''. In this journal, Nocard will publish a great number of scientific papers, on
medicine Medicine is the science and Praxis (process), practice of caring for patients, managing the Medical diagnosis, diagnosis, prognosis, Preventive medicine, prevention, therapy, treatment, Palliative care, palliation of their injury or disease, ...
,
surgery Surgery is a medical specialty that uses manual and instrumental techniques to diagnose or treat pathological conditions (e.g., trauma, disease, injury, malignancy), to alter bodily functions (e.g., malabsorption created by bariatric surgery s ...
,
hygiene Hygiene is a set of practices performed to preserve health. According to the World Health Organization (WHO), "Hygiene refers to conditions and practices that help to maintain health and prevent the spread of diseases." Personal hygiene refer ...
and
jurisprudence Jurisprudence, also known as theory of law or philosophy of law, is the examination in a general perspective of what law is and what it ought to be. It investigates issues such as the definition of law; legal validity; legal norms and values ...
. In 1878 he is approved in a public contest as Professor of Clinical and Surgical Veterinary of the École Veterinaire. Among his many pupils who became famous was Camille Guérin, co-discoverer of the
Bacillus Calmette-Guérin The Bacillus Calmette–Guérin (BCG) vaccine is a vaccine primarily used against tuberculosis (TB). It is named after its inventors Albert Calmette and Camille Guérin. In countries where tuberculosis or leprosy is common, one dose is recom ...
(BCG). In 1880 Nocard entered the laboratory of
Louis Pasteur Louis Pasteur (, ; 27 December 1822 – 28 September 1895) was a French chemist, pharmacist, and microbiologist renowned for his discoveries of the principles of vaccination, Fermentation, microbial fermentation, and pasteurization, the la ...
in
Paris Paris () is the Capital city, capital and List of communes in France with over 20,000 inhabitants, largest city of France. With an estimated population of 2,048,472 residents in January 2025 in an area of more than , Paris is the List of ci ...
as an assistant. There, he helped Pasteur and
Emile Roux Emile or Émile may refer to: * Émile (novel) (1827), autobiographical novel based on Émile de Girardin's early life * Emile, Canadian film made in 2003 by Carl Bessai * '' Emile: or, On Education'' (1762) by Jean-Jacques Rousseau, a treatise o ...
in their classic experiments of
vaccination Vaccination is the administration of a vaccine to help the immune system develop immunity from a disease. Vaccines contain a microorganism or virus in a weakened, live or killed state, or proteins or toxins from the organism. In stimulating ...
of animals against
anthrax Anthrax is an infection caused by the bacterium '' Bacillus anthracis'' or ''Bacillus cereus'' biovar ''anthracis''. Infection typically occurs by contact with the skin, inhalation, or intestinal absorption. Symptom onset occurs between one ...
at Pouilly-le-Fort. In 1883, he traveled to
Egypt Egypt ( , ), officially the Arab Republic of Egypt, is a country spanning the Northeast Africa, northeast corner of Africa and Western Asia, southwest corner of Asia via the Sinai Peninsula. It is bordered by the Mediterranean Sea to northe ...
with Roux, Straus, and Thuiller, in order to study an outbreak of
cholera Cholera () is an infection of the small intestine by some Strain (biology), strains of the Bacteria, bacterium ''Vibrio cholerae''. Symptoms may range from none, to mild, to severe. The classic symptom is large amounts of watery diarrhea last ...
there, but they were unable to isolate the germ responsible for the disease. He returned on the same year to Alfort, and established a well-equipped research laboratory, in close liaison with Pasteur's. In the next three years, Nocard demonstrated his great skills in laboratory work in the new science of
bacteriology Bacteriology is the branch and specialty of biology that studies the Morphology (biology), morphology, ecology, genetics and biochemistry of bacteria as well as many other aspects related to them. This subdivision of microbiology involves the iden ...
by developing a number of new techniques, such as methods of harvesting
blood serum Serum () is the fluid and solvent component of blood which does not play a role in clotting. It may be defined as blood plasma without the clotting factors, or as blood with all cells and clotting factors removed. Serum contains all proteins ex ...
, new
culture media A growth medium or culture medium is a solid, liquid, or semi-solid designed to support the growth of a population of microorganisms or cells via the process of cell proliferation or small plants like the moss ''Physcomitrella patens''. Differen ...
for the bacillus of
tuberculosis Tuberculosis (TB), also known colloquially as the "white death", or historically as consumption, is a contagious disease usually caused by ''Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can al ...
, the introduction of
anesthesia Anesthesia (American English) or anaesthesia (British English) is a state of controlled, temporary loss of sensation or awareness that is induced for medical or veterinary purposes. It may include some or all of analgesia (relief from or prev ...
of large animals with intravenous
chloral hydrate Chloral hydrate is a geminal diol with the formula . It was first used as a sedative and hypnotic in Germany in the 1870s. Over time it was replaced by safer and more effective alternatives but it remained in use in the United States until at ...
, as well as for controlling tetanic
convulsions A convulsion is a medical condition where the body muscles contract and relax rapidly and repeatedly, resulting in uncontrolled shaking. Because epileptic seizures typically include convulsions, the term ''convulsion'' is often used as a synony ...
. His scientific and academic victories were rewarded, in 1887, with the title of director of the School, and chair of
infectious diseases infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable dise ...
, and, in 1888, with an invitation to become a member to the first editorial board of the ''Annals of the Pasteur Institute''. He became a full member of the
Pasteur Institute The Pasteur Institute (, ) is a French non-profit private foundation dedicated to the study of biology, micro-organisms, diseases, and vaccines. It is named after Louis Pasteur, who invented pasteurization and vaccines for anthrax and rabies. Th ...
in 1895. From 1892 to 1896, he strived to convince the medical and general public, in a series of communications, conferences, booklets, and demonstrations, that the use of the
tuberculin Tuberculin, also known as purified protein derivative, is a combination of proteins that are used in the diagnosis of tuberculosis. This use is referred to as the tuberculin skin test and is recommended only for those at high risk. Reliable adm ...
of
Robert Koch Heinrich Hermann Robert Koch ( ; ; 11 December 1843 – 27 May 1910) was a German physician and microbiologist. As the discoverer of the specific causative agents of deadly infectious diseases including tuberculosis, cholera and anthrax, he i ...
could provide the foundations for the prevention of
bovine tuberculosis Bovines (subfamily Bovinae) comprise a diverse group of 10 genera of medium to large-sized ungulates, including cattle, bison, African buffalo, water buffalos, and the four-horned and spiral-horned antelopes. The members of this group are classif ...
. He published in the classic ''La Tuberculose Bovine : ses Dangers, ses Rapports avec la Tuberculose Humaine'' (The Bovine Tuberculosis: Its Dangers and its Relationship with Human Tuberculosis). Nocard’s main contribution to medicine has been the discovery of the genre of
bacteria Bacteria (; : bacterium) are ubiquitous, mostly free-living organisms often consisting of one Cell (biology), biological cell. They constitute a large domain (biology), domain of Prokaryote, prokaryotic microorganisms. Typically a few micr ...
which was named, in his honor, ''
Nocardia ''Nocardia'' is a genus of weakly staining Gram-positive, catalase, catalase-positive, rod-shaped bacteria. It forms partially acid-fast beaded branching filaments (appearing similar to fungi, but being truly bacteria). It contains a total of 8 ...
''. It causes
nocardiosis Nocardiosis is an infectious disease affecting either the lungs (''pulmonary nocardiosis'') or the whole body (''systemic nocardiosis''). It is due to infection by a bacterium of the genus ''Nocardia'', most commonly ''Nocardia asteroides'' or ''N ...
, a disease which manifests itself mainly in animals of economic importance, such as bovine farcy, for which he discovered the first Nocardia, named by him initially as ''Streptothrix farcinica''. The Nocardia may also cause disease in humans, particularly in
immunocompromised Immunodeficiency, also known as immunocompromise, is a state in which the immune system's ability to fight infectious diseases and cancer is compromised or entirely absent. Most cases are acquired ("secondary") due to extrinsic factors that affe ...
patients, such as those with
AIDS The HIV, human immunodeficiency virus (HIV) is a retrovirus that attacks the immune system. Without treatment, it can lead to a spectrum of conditions including acquired immunodeficiency syndrome (AIDS). It is a Preventive healthcare, pr ...
. In the field of veterinary
pathology Pathology is the study of disease. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in the context of modern medical treatme ...
he discovered the pathogen of endozootic
mastitis Mastitis is inflammation of the breast or udder, usually associated with breastfeeding. Symptoms typically include local pain and redness. There is often an associated fever and general soreness. Onset is typically fairly rapid and usually occ ...
, ''Streptococcus agalactiae''. Nocard also discovered the virus which causes bovine peripneumonia and studied
psittacosis Psittacosis—also known as parrot fever, and ornithosis—is a zoonotic infectious disease in humans caused by a bacterium called '' Chlamydia psittaci'' and contracted from infected parrots, such as macaws, cockatiels, and budgerigars, and ...
. He died on 2 August 1903 in Saint-Maurice ( Marne)


External links

*
Edmond Nocard
Pasteur Institute (in French) *
Jean Blancou Jean Blancou (August 28, 1936 (Bangui, Central African Republic The Central African Republic (CAR) is a landlocked country in Central Africa. It is bordered by Chad to Central African Republic–Chad border, the north, Sudan to Central Af ...
br>''Esquisse biographique d'Edmond Nocard''
Bull.soc.fr.hist.méd.sci.vét 2003, 2


References

Chauvau, E Leclainche, E Roux, ''Edmond Nocard 1850-1903'', Paris, Masson and Co éd., 1906, 85 p. {{DEFAULTSORT:Nocard, Edmond 1850 births 1903 deaths People from Provins French biologists French microbiologists French veterinarians