Edgar Allen (May 2, 1892 – February 3, 1943) was an American

anatomist Anatomy () is the branch of morphology concerned with the study of the internal structure of organisms and their parts. Anatomy is a branch of natural science that deals with the structural organization of living things. It is an old scien ...

and

physiologist Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a subdiscipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out chemical and ...

. He is known for the discovery of

estrogen Estrogen (also spelled oestrogen in British English; see spelling differences) is a category of sex hormone responsible for the development and regulation of the female reproductive system and secondary sex characteristics. There are three ...

and his role in creating the field of

endocrinology Endocrinology (from ''endocrine system, endocrine'' + ''wikt:-logy#Suffix, -ology'') is a branch of biology and medicine dealing with the endocrine system, its diseases, and its specific secretions known as hormones. It is also concerned with the ...

. Born on Cañon (Canyon) City,

Colorado Colorado is a U.S. state, state in the Western United States. It is one of the Mountain states, sharing the Four Corners region with Arizona, New Mexico, and Utah. It is also bordered by Wyoming to the north, Nebraska to the northeast, Kansas ...

, Allen was educated at

Brown University Brown University is a Private university, private Ivy League research university in Providence, Rhode Island, United States. It is the List of colonial colleges, seventh-oldest institution of higher education in the US, founded in 1764 as the ' ...

. After serving in

World War I World War I or the First World War (28 July 1914 – 11 November 1918), also known as the Great War, was a World war, global conflict between two coalitions: the Allies of World War I, Allies (or Entente) and the Central Powers. Fighting to ...

he took a position at

Washington University School of Medicine Washington University School of Medicine (WashU Medicine) is the medical school of Washington University in St. Louis, located in the Central West End neighborhood of St. Louis, Missouri. Founded in 1891, the School of Medicine shares a ca ...

in 1919 until, in 1923, he was appointed to the chair of anatomy at the

University of Missouri The University of Missouri (Mizzou or MU) is a public university, public Land-grant university, land-grant research university in Columbia, Missouri, United States. It is Missouri's largest university and the flagship of the four-campus Univers ...

Columbia, Missouri Columbia is a city in Missouri, United States. It was founded in 1821 as the county seat of Boone County, Missouri, Boone County and had a population of 126,254 as recorded in the 2020 United States census, making it the List of cities in Misso ...

. Ten years later he was appointed to the chair at

Yale University Yale University is a Private university, private Ivy League research university in New Haven, Connecticut, United States. Founded in 1701, Yale is the List of Colonial Colleges, third-oldest institution of higher education in the United Stat ...

. At Missouri, he began his studies of

sex hormones Sex hormones, also known as sex steroids, gonadocorticoids and gonadal steroids, are steroid hormones that interact with vertebrate steroid hormone receptors. The sex hormones include the androgens, estrogens, and progestogens. Their effects a ...

. While it was commonly believed at the time that the female reproductive cycle was controlled by substance in the ''

corpus luteum The corpus luteum (Latin for "yellow body"; : corpora lutea) is a temporary endocrine structure in female ovaries involved in the production of relatively high levels of progesterone, and moderate levels of estradiol, and inhibin A. It is the ...

'', Allen sought the answer in the follicles surrounding the

ovum The egg cell or ovum (: ova) is the female reproductive cell, or gamete, in most anisogamous organisms (organisms that reproduce sexually with a larger, female gamete and a smaller, male one). The term is used when the female gamete is not capa ...

, leading to his discovery of estrogen, though it was identified six years later by

Adolf Butenandt Adolf Friedrich Johann Butenandt (; 24 March 1903 – 18 January 1995) was a German biochemist. He was awarded the Nobel Prize in Chemistry in 1939 for his "work on sex hormones." He initially rejected the award in accordance with government pol ...

in 1929. He served as the 25th president of the American Association of Anatomists from 1942 to 1943. Allen died of a heart attack in 1943 while on duty with the

United States Coast Guard The United States Coast Guard (USCG) is the maritime security, search and rescue, and Admiralty law, law enforcement military branch, service branch of the armed forces of the United States. It is one of the country's eight Uniformed services ...

References

External links

Biography of Edgar Allen on whonamedit.com
{{DEFAULTSORT:Allen, Edgar American anatomists American physiologists Brown University alumni University of Missouri faculty Yale University faculty People from Cañon City, Colorado 1892 births 1943 deaths Washington University School of Medicine faculty

References

Further reading

External links