Ectoine Synthase
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The
enzyme An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different mol ...
ectoine synthase ()
catalyzes Catalysis () is the increase in rate of a chemical reaction due to an added substance known as a catalyst (). Catalysts are not consumed by the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recycles quick ...
the
chemical reaction A chemical reaction is a process that leads to the chemistry, chemical transformation of one set of chemical substances to another. When chemical reactions occur, the atoms are rearranged and the reaction is accompanied by an Gibbs free energy, ...
:(2''S'')-4-acetamido-2-aminobutanoate \rightleftharpoons L-ectoine + H2O This enzyme belongs to the family of
lyase In biochemistry, a lyase is an enzyme that catalyzes the breaking (an elimination reaction) of various chemical bonds by means other than hydrolysis (a substitution reaction) and oxidation Redox ( , , reduction–oxidation or oxidatio ...
s, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The
systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivi ...
of this enzyme class is (2''S'')-4-acetamido-2-aminobutanoate (L-ectoine-forming). Other names in common use include ''N''-acetyldiaminobutyrate dehydratase, ''N''-acetyldiaminobutanoate dehydratase, L-ectoine synthase, EctC, and 4-''N''-acetyl-L-2,4-diaminobutanoate hydro-lyase (L-ectoine-forming). This enzyme participates in
glycine Glycine (symbol Gly or G; ) is an amino acid that has a single hydrogen atom as its side chain. It is the simplest stable amino acid. Glycine is one of the proteinogenic amino acids. It is encoded by all the codons starting with GG (G ...
,
serine Serine (symbol Ser or S) is an α-amino acid that is used in the biosynthesis of proteins. It contains an α- amino group (which is in the protonated − form under biological conditions), a carboxyl group (which is in the deprotonated − ...
and
threonine metabolism Threonine (symbol Thr or T) is an amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH form when dissolved in water), a carboxyl group (which is in the deprotonated −COO− fo ...
.


References

* * * * EC 4.2.1 Enzymes of unknown structure {{4.2-enzyme-stub