Protein argonaute-2 is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respon ...
that in humans is encoded by the ''EIF2C2''
gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...
.
This gene encodes a member of the
Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a
PAZ domain and a
PIWI domain. It may interact with
Dicer1 and play a role in short-interfering-RNA-mediated gene silencing.
Interactions
EIF2C2 has been shown to
interact with
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DDX20,
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DICER1,
References
Further reading
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RNA interference
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