Early growth response protein 3 is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metab ...
in humans, encoded by the ''EGR3''
gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protei ...
.
The gene encodes a
transcriptional regulator that belongs to the
EGR family of C2H2-type
zinc-finger proteins. It is an immediate-early growth response gene which is induced by
mitogenic
A mitogen is a small bioactive protein or peptide that induces a cell to begin cell division, or enhances the rate of division (mitosis). Mitogenesis is the induction (triggering) of mitosis, typically via a mitogen.
The cell cycle
Mitogens ac ...
stimulation. The protein encoded by this gene participates in the transcriptional regulation of genes in controlling
biological rhythm. It may also play a role in
muscle
Muscle is a soft tissue, one of the four basic types of animal tissue. There are three types of muscle tissue in vertebrates: skeletal muscle, cardiac muscle, and smooth muscle. Muscle tissue gives skeletal muscles the ability to muscle contra ...
development.
References
Further reading
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External links
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Transcription factors
{{gene-8-stub