Ephrin B1 is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metab ...
that in humans is encoded by the ''EFNB1''
gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protei ...
.
It is a member of the
ephrin family. The encoded protein is a
type I membrane protein and a ligand of Eph-related
receptor tyrosine kinases. It may play a role in
cell adhesion
Cell adhesion is the process by which cells interact and attach to neighbouring cells through specialised molecules of the cell surface. This process can occur either through direct contact between cell surfaces such as Cell_junction, cell junc ...
and function in the development or maintenance of the nervous system.
Clinical significance
Mutations in this protein are responsible for most cases of
craniofrontonasal syndrome.
Interactions
EFNB1 has been shown to
interact with
SDCBP.
References
Further reading
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
External links
*
*
Genes on human chromosome X
{{gene-X-stub