EC 3.6
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This list contains a list of EC numbers for the third group, EC 3,
hydrolases In biochemistry, hydrolases constitute a class of enzymes that commonly function as biochemical catalysts that use water to break a chemical bond: :\ce \quad \xrightarrowtext\quad \ce This typically results in dividing a larger molecule into s ...
, placed in numerical order as determined by the Nomenclature Committee of the
International Union of Biochemistry and Molecular Biology The International Union of Biochemistry and Molecular Biology (IUBMB) is an international non-governmental organisation concerned with biochemistry and molecular biology. Formed in 1955 as the International Union of Biochemistry (IUB), the union ...
. All official information is tabulated at the website of the committee. The database is developed and maintained by Andrew McDonald.


EC 3.1: Acting on Ester Bonds


EC 3.1.1: Carboxylic Ester Hydrolases

* :
carboxylesterase The enzyme carboxylesterase (or carboxylic-ester hydrolase, EC 3.1.1.1; systematic name carboxylic-ester hydrolase) catalysis, catalyzes reactions of the following form: :a Ester, carboxylic ester + H2O \rightleftharpoons an Alcohol (chemistry), ...
* : arylesterase * : triacylglycerol lipase * : phospholipase A2 * :
lysophospholipase The enzyme lysophospholipase (EC 3.1.1.5) catalyzes the reaction :2-lysophosphatidylcholine + H2O \rightleftharpoons glycerophosphocholine + a carboxylate This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ...
* :
acetylesterase In biochemistry, an acetylesterase () is a class of enzyme which catalyzes the hydrolysis of acetic esters into an alcohol and acetic acid: :\ce \quad \xrightarrowtext\quad \ce This enzyme belongs to the family of hydrolases, specifically thos ...
* :
acetylcholinesterase Acetylcholinesterase (HUGO Gene Nomenclature Committee, HGNC symbol ACHE; EC 3.1.1.7; systematic name acetylcholine acetylhydrolase), also known as AChE, AChase or acetylhydrolase, is the primary cholinesterase in the body. It is an enzyme th ...
* :
cholinesterase The enzyme cholinesterase (EC 3.1.1.8, choline esterase; systematic name acylcholine acylhydrolase) catalyses the hydrolysis of choline-based esters: : an acylcholine + H2O = choline + a carboxylate Several of these serve as neurotransmitte ...
* EC 3.1.1.9: deleted, a side reaction of cholinesterase * :
tropinesterase The enzyme tropinesterase (EC 3.1.1.10) catalyzes the reaction :atropine + H2O \rightleftharpoons tropine + tropate This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name A sys ...
* :
pectinesterase Pectinesterase (EC 3.1.1.11; systematic name pectin pectylhydrolase) is a ubiquitous cell-wall-associated enzyme that presents several isoforms that facilitate plant cell wall modification and subsequent breakdown. It catalyzes the following rea ...
* EC 3.1.1.12: deleted, identical with carboxylesterase * : sterol esterase * : chlorophyllase * : L-arabinonolactonase * EC 3.1.1.16: deleted, mixture of (muconolactone Δ-isomerase) and (3-oxoadipate enol-lactonase) * : gluconolactonase * EC 3.1.1.18: deleted, now included with gluconolactonase * :
uronolactonase The enzyme uronolactonase (EC 3.1.1.19) catalyzes the reaction :D-glucurono-6,2-lactone + H2O \rightleftharpoons D-glucuronate This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic ...
* :
tannase The enzyme tannase (EC 3.1.1.20) catalyzes the following reaction: : digallate + H2O = 2 gallate It is a key enzyme in the degradation of gallotannins and ellagicitannins, two types of hydrolysable tannins. Specifically, tannase catalyzes the ...
* EC 3.1.1.21: deleted, now known to be catalysed by , carboxylesterase and , triacylglycerol lipase. * : hydroxybutyrate-dimer hydrolase * :
acylglycerol lipase Monoacylglycerol lipase (EC 3.1.1.23; systematic name glycerol-ester acylhydrolase, also known as MAG lipase, acylglycerol lipase, MAGL, MGL or MGLL) is an enzyme that, in humans, is encoded by the ''MGLL'' gene. MAGL is a 33-kDa, membrane-associ ...
* :
3-oxoadipate enol-lactonase The enzyme 3-oxoadipate enol-lactonase (EC 3.1.1.24) catalyzes the reaction :3-oxoadipate enol-lactone + H2O \rightleftharpoons 3-oxoadipate This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. T ...
* :
1,4-lactonase The enzyme 1,4-lactonase (EC 3.1.1.25) catalyzes the generic reaction :a 1,4-lactone + H2O \rightleftharpoons a 4-hydroxyacid This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic n ...
* :
galactolipase The enzyme galactolipase (EC 3.1.1.26) catalyzes the reaction :1,2-diacyl-3-β-D-galactosyl-''sn''-glycerol + 2 H2O \rightleftharpoons 3-β-D-galactosyl-''sn''-glycerol + 2 carboxylates This enzyme belongs to the family of hydrolases, specificall ...
* :
4-pyridoxolactonase The enzyme 4-pyridoxolactonase (EC 3.1.1.27) catalyzes the reaction :4-pyridoxolactone + H2O \rightleftharpoons 4-pyridoxate This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic na ...
* :
acylcarnitine hydrolase The enzyme acylcarnitine hydrolase (EC 3.1.1.28) catalyzes the reaction :''O''-acylcarnitine + H2O \rightleftharpoons a fatty acid + L-carnitine This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bond ...
* :
aminoacyl-tRNA hydrolase The enzyme aminoacyl-tRNA hydrolase (EC 3.1.1.29) catalyzes the reaction :''N''-substituted aminoacyl-tRNA + H2O \rightleftharpoons ''N''-substituted amino acid + tRNA This enzyme belongs to the family of hydrolases, specifically those acting on ...
* : D-arabinonolactonase * :
6-phosphogluconolactonase 6-Phosphogluconolactonase (EC 3.1.1.31, 6PGL, PGLS, systematic name 6-phospho-D-glucono-1,5-lactone lactonohydrolase) is a cytosolic enzyme found in all organisms that catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconic acid ...
* : phospholipase A1 * :
6-acetylglucose deacetylase The enzyme 6-acetylglucose deacetylase (EC 3.1.1.33) catalyzes the reaction :6-acetyl-D-glucose + H2O \rightleftharpoons D-glucose + acetate This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. ...
* :
lipoprotein lipase Lipoprotein lipase (LPL) (EC 3.1.1.34, systematic name triacylglycerol acylhydrolase (lipoprotein-dependent)) is a member of the lipase gene family, which includes pancreatic lipase, hepatic lipase, and endothelial lipase. It is a water-solubl ...
* :
dihydrocoumarin hydrolase The enzyme dihydrocoumarin hydrolase (EC 3.1.1.35) catalyzes the reaction :dihydrocoumarin + H2O \rightleftharpoons melilotate This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic n ...
* : limonin-D-ring-lactonase * : steroid-lactonase * : triacetate-lactonase * :
actinomycin lactonase The enzyme actinomycin lactonase (EC 3.1.1.39) catalyzes the reaction :actinomycin + H2O \rightleftharpoons actinomycinic monolactone This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The syst ...
* :
orsellinate-depside hydrolase The enzyme orsellinate-depside hydrolase (EC 3.1.1.40) catalysis, catalyzes the reaction :orsellinate depside + H2O \rightleftharpoons 2 orsellinate This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bo ...
* : cephalosporin-C deacetylase * :
chlorogenate hydrolase The enzyme chlorogenate hydrolase (EC 3.1.1.42) catalyzes the reaction :chlorogenate + H2O \rightleftharpoons caffeate + quinate This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic ...
* : α-amino-acid esterase * :
4-methyloxaloacetate esterase The enzyme 4-methyloxaloacetate esterase (EC 3.1.1.44) catalyzes the reaction :oxaloacetate 4-methyl ester + H2O \rightleftharpoons oxaloacetate + methanol This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ...
* :
carboxymethylenebutenolidase In enzymology, a carboxymethylenebutenolidase (, also known as CMBL and dienelactone hydrolase) is an enzyme that catalyzes the chemical reaction :4-carboxymethylenebut-2-en-4-olide + H2O \rightleftharpoons 4-oxohex-2-enedioate Thus, the two su ...
* : deoxylimonate A-ring-lactonase * :
1-alkyl-2-acetylglycerophosphocholine esterase The enzyme 1-alkyl-2-acetylglycerophosphocholine esterase (EC 3.1.1.47) catalyzes the reaction :1-alkyl-2-acetyl-''sn''-glycero-3-phosphocholine + H2O \rightleftharpoons 1-alkyl-''sn''-glycero-3-phosphocholine + acetate The former is also known ...
* : fusarinine-C ornithinesterase * :
sinapine esterase The enzyme sinapine esterase (EC 3.1.1.49) catalysis, catalyzes the reaction :sinapoylcholine + H2O \rightleftharpoons sinapate + choline This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The L ...
* : wax-ester hydrolase * :
phorbol-diester hydrolase The enzyme phorbol-diester hydrolase (EC 3.1.1.51) catalyzes the reaction :phorbol 12,13-dibutanoate + H2O \rightleftharpoons phorbol 13-butanoate + butanoate This enzyme belongs to the family of hydrolases, specifically those acting on carboxyli ...
* :
phosphatidylinositol deacylase The enzyme phosphatidylinositol deacylase (EC 3.1.1.52) catalyzes the reaction :1-phosphatidyl-D-''myo''-inositol + H2O \rightleftharpoons 1-acylglycerophosphoinositol + a carboxylate This enzyme belongs to the family of hydrolases, specifically ...
* : sialate ''O''-acetylesterase * :
acetoxybutynylbithiophene deacetylase The enzyme acetoxybutynylbithiophene deacetylase (EC 3.1.1.54) catalyzes the reaction :5-(4-acetoxybut-1-ynyl)-2,2′-bithiophene + H2O \rightleftharpoons 5-(4-hydroxybut-1-ynyl)-2,2′-bithiophene + acetate This enzyme belongs to the family of ...
* :
acetylsalicylate deacetylase The enzyme acetylsalicylate deacetylase (EC 3.1.1.55) catalyzes the reaction :acetylsalicylate + H2O \rightleftharpoons salicylate + acetate This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. T ...
* :
methylumbelliferyl-acetate deacetylase The enzyme methylumbelliferyl-acetate deacetylase (EC 3.1.1.56, esterase D) catalyzes the reaction :4-methylumbelliferyl acetate + H2O \rightleftharpoons 4-methylumbelliferone + acetate This enzyme belongs to the family of hydrolases, specifical ...
* : 2-pyrone-4,6-dicarboxylate lactonase * : ''N''-acetylgalactosaminoglycan deacetylase * :
juvenile-hormone esterase The enzyme juvenile hormone esterase (EC 3.1.1.59, systematic name methyl-(2''E'',6''E'',10''R'')-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate acylhydrolase, JH esterase) catalyzes the hydrolysis of juvenile hormone: :(1) juvenile hormone I + ...
* :
bis(2-ethylhexyl)phthalate esterase The enzyme bis(2-ethylhexyl)phthalate esterase (EC 3.1.1.60) catalyzes the reaction :bis(2-ethylhexyl)phthalate + H2O \rightleftharpoons 2-ethylhexyl phthalate + 2-ethylhexan-1-ol This enzyme belongs to the family of hydrolases, specifically th ...
* : protein-glutamate methylesterase * EC 3.1.1.62: Now listed as , ''N''-acetyldiaminopimelate deacetylase * : 11-''cis''-retinyl-palmitate hydrolase * : retinoid isomerohydrolase * : L-rhamnono-1,4-lactonase * : 5-(3,4-diacetoxybut-1-ynyl)-2,2′-bithiophene deacetylase * : fatty-acyl-ethyl-ester synthase * : xylono-1,4-lactonase * EC 3.1.1.69: Now , ''N''-acetylglucosaminylphosphatidylinositol deacetylase * :
cetraxate benzylesterase The enzyme cetraxate benzylesterase (EC 3.1.1.70) catalyzes the reaction :cetraxate benzyl ester + H2O \rightleftharpoons cetraxate + benzyl alcohol This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bo ...
* :
acetylalkylglycerol acetylhydrolase The enzyme acetylalkylglycerol acetylhydrolase (EC 3.1.1.71) catalysis, catalyzes the reaction :2-acetyl-1-alkyl-''sn''-glycerol + H2O \rightleftharpoons 1-alkyl-''sn''-glycerol + acetate This enzyme belongs to the family of hydrolases, specific ...
* :
acetylxylan esterase The enzyme acetylxylan esterase (EC 3.1.1.72) catalyzes the deacetylation of xylans and xylo-oligosaccharides. This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name is acetylxyl ...
* :
feruloyl esterase The enzyme feruloyl esterase (EC 3.1.1.73) catalyzes the reaction :feruloyl-polysaccharide + H2O \rightleftharpoons ferulate + polysaccharide This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. ...
* :
cutinase The enzyme cutinase (systematic name: cutin hydrolaseEC 3.1.1.74 is a member of the hydrolase family. It catalyzes the following reaction: : R1COOR2 + H2O -> R1COOH + R2OH In biological systems, the reactant carboxylic ester is a constituent of ...
* : poly(3-hydroxybutyrate) depolymerase * :
poly(3-hydroxyoctanoate) depolymerase The enzyme poly(3-hydroxyoctanoate) depolymerase (EC 3.1.1.76) catalyzes the hydrolysis of the polyester poly{oxycarbonyl ''R'')-2-pentylethyleneto oligomers This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ...
* : acyloxyacyl hydrolase * :
polyneuridine-aldehyde esterase The enzyme polyneuridine-aldehyde esterase (EC 3.1.1.78) catalysis, catalyzes the following reaction: :polyneuridine aldehyde + H2O \rightleftharpoons 16-epivellosimine + CO2 + methanol This enzyme participates in indole alkaloid biosynthesis. ...
* :
hormone-sensitive lipase Hormone-sensitive lipase (, HSL), also previously known as cholesteryl ester hydrolase (CEH), sometimes referred to as triacylglycerol lipase, is an enzyme that, in humans, is encoded by the ''LIPE'' gene, and catalyzes the following reaction: ...
* : acetylajmaline esterase * : quorum-quenching ''N''-acyl-homoserine lactonase * : pheophorbidase * : monoterpene ε-lactone hydrolase * :
cocaine esterase The chloride cocaine esterase (EC 3.1.1.84, CocE, hCE2, hCE-2, human carboxylesterase 2; systematic name cocaine benzoylhydrolase) catalyses the reaction : cocaine + H2O \rightleftharpoons ecgonine methyl ester + benzoate ''Rhodococcus'' sp. s ...
* :
pimelyl-(acyl-carrier protein) methyl ester esterase The enzyme Pimelyl- cyl-carrier proteinmethyl ester esterase (EC 3.1.1.85, BioH; systematic name pimelyl- cyl-carrier proteinmethyl ester hydrolase catalyses the reaction : pimelyl- cyl-carrier proteinmethyl ester + H2O \rightleftharpoons pimelyl ...
* : rhamnogalacturonan acetylesterase * :
fumonisin B1 esterase The enzyme fumonisin B1 esterase (EC 3.1.1.87, fumD (gene); systematic name fumonisin B1 acylhydrolase) catalyses the reaction : fumonisin B1 Fumonisin B1 is the most prevalent member of a family of toxins, known as fumonisins, produced by mul ...
* :
pyrethroid hydrolase The enzyme pyrethroid hydrolase (EC 3.1.1.88, pyrethroid-hydrolyzing carboxylesterase, pyrethroid-hydrolysing esterase, pyrethroid-hydrolyzing esterase, pyrethroid-selective esterase, pyrethroid-cleaving enzyme, permethrinase, PytH, EstP; systemati ...
* :
protein phosphatase methylesterase-1 The enzyme protein phosphatase methylesterase-1 (EC 3.1.1.89, PME-1, PPME1; systematic name (phosphatase 2A protein)-leucine ester acylhydrolase catalyses the reaction : hosphatase 2A proteinleucine methyl ester + H2O \rightleftharpoons hospha ...
* : ''all-trans''-retinyl ester 13-''cis'' isomerohydrolase * : 2-oxo-3-(5-oxofuran-2-ylidene)propanoate lactonase * : 4-sulfomuconolactone hydrolase * :
mycophenolic acid acyl-glucuronide esterase The enzyme mycophenolic acid acyl-glucuronide esterase (EC 3.1.1.93, mycophenolic acid acyl-glucuronide deglucuronidase; AcMPAG deglucuronidase; systematic name mycophenolic acid ''O''-acyl-glucuronide-ester hydrolase), is in humans encoded by the ' ...
* : versiconal hemiacetal acetate esterase * * : aclacinomycin methylesterase * * : D-aminoacyl-tRNA deacylase * * : methylated diphthine methylhydrolase * * : nt protein''O''-palmitoleoyl-L-serine hydrolase * * : 6-deoxy-6-sulfogluconolactonase * * : chlorophyllide a hydrolase * * : poly(ethylene terephthalate) hydrolase * * : mono(ethylene terephthalate) hydrolase * * : teichoic acid D-alanine hydrolase * * : 5-phospho-D-xylono-1,4-lactonase * * : 3-''O''-acetylpapaveroxine carboxylesterase * * : ''O''-acetyl-ADP-ribose deacetylase * * : apo-salmochelin esterase * * : iron(III)-enterobactin esterase * * : iron(III)-salmochelin esterase * * : xylono-1,5-lactonase * * : phosphatidylserine ''sn''-1 acylhydrolase * * : isoamyl acetate esterase * * : ethyl acetate hydrolase * * :
methyl acetate hydrolase Methyl acetate hydrolase, known also as ''methylacetate acetohydrolase'' is a hydrolase enzyme that utilizes to carry out the hydrolysis of methyl acetate (CH3COOCH3), a weakly lipophillic and polar compound used often as a solvent. In the sp ...
* : D-apionolactonase * * : ''sn''-1-specific diacylglycerol lipase * * : (4-''O''-methyl)-D-glucuronate—lignin esterase * * : phospholipid ''sn''-1 acylhydrolase * : *No Wikipedia article


EC 3.1.2: Thioester Hydrolases

* : acetyl-CoA hydrolase * :
palmitoyl-CoA hydrolase Palmitoyl-CoA hydrolase (EC 3.1.2.2) is an enzyme in the family of hydrolases that specifically acts on thioester bonds. It catalyzes the hydrolysis of long chain fatty acyl thioesters of acyl carrier protein or coenzyme A to form free fatty acid a ...
* : succinyl-CoA hydrolase * : 3-hydroxyisobutyryl-CoA hydrolase * :
hydroxymethylglutaryl-CoA hydrolase The enzyme hydroxymethylglutaryl-CoA hydrolase (EC 3.1.2.5) catalyzes the reaction :''S''-(2-hydroxyacyl)glutathione + H2O = glutathione + a 2-hydroxy carboxylate This enzyme belongs to the family of hydrolases, specifically those acting on thioe ...
* : hydroxyacylglutathione hydrolase * : glutathione thiolesterase * EC 3.1.2.8: Now included with hydroxyacylglutathione hydrolase * EC 3.1.2.9: ''S''-acetoacetylhydrolipoate hydrolase deleted * : formyl-CoA hydrolase * :
acetoacetyl-CoA hydrolase The enzyme acetoacetyl-CoA hydrolase (EC 3.1.2.11) catalyzes the reaction :acetoacetyl-CoA + H2O \rightleftharpoons CoA + acetoacetate This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic ...
* : ''S''-formylglutathione hydrolase * : ''S''-succinylglutathione hydrolase * : oleoyl- cyl-carrier-proteinhydrolase * EC 3.1.2.15: covered by , ubiquitinyl hydrolase 1 * :
citrate lyase deacetylase The enzyme citrate lyase deacetylase (EC 3.1.2.16) catalyzes the reaction :acetyl- itrate (pro-3''S'')-lyase+ H2O = holo- itrate (pro-3''S'')-lyase+ acetate This enzyme belongs to the family of hydrolases, specifically those acting on thioester ...
* : (''S'')-methylmalonyl-CoA hydrolase * : ADP-dependent short-chain-acyl-CoA hydrolase * :
ADP-dependent medium-chain-acyl-CoA hydrolase The enzyme ADP-dependent medium-chain-acyl-CoA hydrolase (EC 3.1.2.19) catalyzes the reaction :acyl-CoA + H2O \rightleftharpoons CoA + a carboxylate This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. T ...
* : acyl-CoA hydrolase * :
dodecanoyl-(acyl-carrier-protein) hydrolase The enzyme dodecanoyl- cyl-carrier-proteinhydrolase (EC 3.1.2.21) catalyzes the reaction :a dodecanoyl- cyl-carrier-protein+ H2O \rightleftharpoons an cyl-carrier-protein+ dodecanoate This enzyme belongs to the family of hydrolases, specificall ...
* : palmitoyl roteinhydrolase * : 4-hydroxybenzoyl-CoA thioesterase * EC 3.1.2.24: transferred entry now , 2′-hydroxybiphenyl-2-sulfinate desulfinase. * :
phenylacetyl-CoA hydrolase The enzyme phenylacetyl-CoA hydrolase (EC 3.1.2.25) catalyzes the reaction :phenylglyoxylyl-CoA + H2O \rightleftharpoons phenylglyoxylate + CoA This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The sy ...
* EC 3.1.2.26: Now , bile acid CoA transferase * :
choloyl-CoA hydrolase The enzyme choloyl-CoA hydrolase (EC 3.1.2.27) catalyzes the reaction :choloyl-CoA + H2O \rightleftharpoons cholate + CoA This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name A syst ...
* : 1,4-dihydroxy-2-naphthoyl-CoA hydrolase * :
fluoroacetyl-CoA thioesterase The enzyme fluoroacetyl-CoA thioesterase (EC 3.1.2.29; systematic name fluoroacetyl-CoA hydrolase) catalyses the following reaction: : fluoroacetyl-CoA + H2O \rightleftharpoons fluoroacetate + CoA Fluoroacetate is extremely toxic Toxicity ...
* : (3''S'')-malyl-CoA thioesterase * * : dihydromonacolin L- ovastatin nonaketide synthasethioesterase * * : 2-aminobenzoylacetyl-CoA thioesterase * : *No Wikipedia article


EC 3.1.3: Phosphoric Monoester Hydrolases

* :
alkaline phosphatase The enzyme alkaline phosphatase (ALP, alkaline phenyl phosphatase, also abbreviated PhoA) is a phosphatase with the physiological role of dephosphorylating compounds. The enzyme is found across a multitude of organisms, prokaryotes and eukaryo ...
* :
acid phosphatase Acid phosphatase (EC 3.1.3.2, systematic name ''phosphate-monoester phosphohydrolase (acid optimum)'') is an enzyme that frees attached phosphoryl groups from other molecules during digestion. It can be further classified as a phosphoric monoeste ...
* : phosphoserine phosphatase * : phosphatidate phosphatase * : 5′-nucleotidase * : 3′-nucleotidase * : 3′(2′),5′-bisphosphate nucleotidase * :
3-phytase The enzyme 3-phytase (EC 3.1.3.8) catalyzes the reaction : ''myo''-inositol hexakisphosphate + H2O = 1D-''myo''-inositol 1,2,4,5,6-pentakisphosphate + phosphate ''myo''-Inositol hexakisphosphate is also known as phytic acid. These enzymes belon ...
* :
glucose-6-phosphatase The enzyme glucose 6-phosphatase (EC 3.1.3.9, G6Pase; systematic name D-glucose-6-phosphate phosphohydrolase) catalyzes the hydrolysis of glucose 6-phosphate, resulting in the creation of a phosphate group and free glucose: : D-glucose 6-pho ...
* :
glucose-1-phosphatase The enzyme glucose-1-phosphatase (EC 3.1.3.10) catalyzes the reaction :α-D-glucose 1-phosphate + H2O \rightleftharpoons D-glucose + phosphate This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bond ...
* : fructose-bisphosphatase * :
trehalose-phosphatase The enzyme trehalose-phosphatase (EC 3.1.3.12) catalyzes the reaction :α,α-trehalose 6-phosphate + H2O \rightleftharpoons α,α-trehalose + phosphate This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoe ...
* EC 3.1.3.13: Recent studies have shown that this is a partial activity of , phosphoglycerate mutase (2,3-diphosphoglycerate-dependent) * :
methylphosphothioglycerate phosphatase The enzyme methylphosphothioglycerate phosphatase (EC 3.1.3.14) catalyzes the reaction :''S''-methyl-3-phospho-1-thio-D-glycerate + H2O \rightleftharpoons ''S''-methyl-1-thio-D-glycerate + phosphate This enzyme belongs to the family of hydrolases ...
* : histidinol-phosphatase * : protein serine/threonine phosphatase * :
(phosphorylase) phosphatase The enzyme phosphorylase a phosphatase (EC 3.1.3.17) catalyzes the reaction : hosphorylase ''a''+ 4 HO \rightleftharpoons 2 hosphorylase ''b''+ 4 phosphate It is synonymous with Protein phosphatase 1. This enzyme belongs to the family of hydro ...
* : phosphoglycolate phosphatase * : glycerol-2-phosphatase * :
phosphoglycerate phosphatase The enzyme phosphoglycerate phosphatase (EC 3.1.3.20) catalyzes the reaction :D-glycerate 2-phosphate + H2O \rightleftharpoons D-glycerate + phosphate This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoes ...
* :
glycerol-1-phosphatase The enzyme glycerol-1-phosphatase (EC 3.1.3.21) catalyzes the reaction :glycerol 1-phosphate + H2O \rightleftharpoons glycerol + phosphate This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. ...
* : mannitol-1-phosphatase * :
sugar-phosphatase The enzyme sugar-phosphatase (EC 3.1.3.23) catalyzes the reaction :sugar phosphate + H2O \rightleftharpoons sugar + phosphate This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systemati ...
* :
sucrose-phosphatase The enzyme sucrose-phosphatase (EC 3.1.3.24) catalyzes the reaction :sucrose 6''F''-phosphate + H2O \rightleftharpoons sucrose + phosphate This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. ...
* :
inositol-phosphate phosphatase The enzyme Inositol phosphate-phosphatase (EC 3.1.3.25) is of the phosphodiesterase family of enzymes. It is involved in the phosphophatidylinositol signaling pathway, which affects a wide array of cell functions, including but not limited to ...
* : 4-phytase * :
phosphatidylglycerophosphatase The enzyme phosphatidylglycerophosphatase (EC 3.1.3.27) catalyzes the following reaction: :phosphatidylglycerophosphate + H2O \rightleftharpoons phosphatidylglycerol + phosphate This enzyme belongs to the family of hydrolases, specifically those ...
* :
ADP-phosphoglycerate phosphatase The enzyme ADP-phosphoglycerate phosphatase (EC 3.1.3.28) catalyzes the reaction :3-(ADP)-2-phosphoglycerate + H2O \rightleftharpoons 3-(ADP)-glycerate + phosphate This enzyme belongs to the family of hydrolases, specifically those acting on phos ...
* : ''N''-acylneuraminate-9-phosphatase * EC 3.1.3.30: The activity may be that of an acid phosphatase * EC 3.1.3.31: The activity may be that of an acid phosphatase * : polynucleotide 3′-phosphatase * : polynucleotide 5′-phosphatase * : deoxynucleotide 3′-phosphatase * : thymidylate 5′-phosphatase * :
phosphoinositide 5-phosphatase The enzyme phosphoinositide 5-phosphatase (EC 3.1.3.36) catalyzes the reaction :1-phosphatidyl-1D-''myo''-inositol 4,5-bisphosphate + H2O \rightleftharpoons 1-phosphatidyl-1D-''myo''-inositol 4-phosphate + phosphate This enzyme belongs to the fam ...
* : sedoheptulose-bisphosphatase * :
3-phosphoglycerate phosphatase The enzyme 3-phosphoglycerate phosphatase (EC 3.1.3.38) catalyzes the reaction :D-glycerate 3-phosphate + H2O \rightleftharpoons D-glycerate + phosphate This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric mon ...
* :
streptomycin-6-phosphatase The enzyme streptomycin-6-phosphatase (EC 3.1.3.39) catalyzes the reaction :streptomycin 6-phosphate + H2O \rightleftharpoons streptomycin + phosphate This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoes ...
* : guanidinodeoxy-''scyllo''-inositol-4-phosphatase * : 4-nitrophenylphosphatase * : glycogen-synthase-Dphosphatase * : (pyruvate dehydrogenase (acetyl-transferring))-phosphatase"> cetyl-CoA carboxylasephosphatase * : 3-deoxy-''manno''-octulosonate-8-phosphatase * : fructose-2,6-bisphosphate 2-phosphatase * : ydroxymethylglutaryl-CoA reductase (NADPH)phosphatase * :
protein-tyrosine-phosphatase Protein tyrosine phosphatases (EC 3.1.3.48, systematic name protein-tyrosine-phosphate phosphohydrolase) are a group of enzymes that remove phosphate groups from phosphorylated tyrosine residues on proteins: : proteintyrosine phosphate + H2O = ...
* : yruvate kinasephosphatase * :
sorbitol-6-phosphatase The enzyme sorbitol-6-phosphatase (EC 3.1.3.50) catalyzes the reaction :sorbitol 6-phosphate + H2O \rightleftharpoons sorbitol + phosphate This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. ...
* :
dolichyl-phosphatase The enzyme dolichyl-phosphatase (EC 3.1.3.51) catalyzes the reaction :dolichyl phosphate + H2O \rightleftharpoons dolichol + phosphate This enzyme belongs to the family of hydrolases, to be specific, those acting on phosphoric monoester bonds. T ...
* : -methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)phosphatase * : yosin-light-chainphosphatase * : fructose-2,6-bisphosphate 6-phosphatase * :
caldesmon-phosphatase The enzyme caldesmon-phosphatase (EC 3.1.3.55) catalyzes the reaction :caldesmon phosphate + H2O \rightleftharpoons caldesmon + phosphate This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. T ...
* :
inositol-polyphosphate 5-phosphatase The enzyme inositol-polyphosphate 5-phosphatase (), systematic name 1D-''myo''-inositol-1,4,5-trisphosphate 5-phosphohydrolase, catalyses the following reactions: : (1) D-''myo''-inositol 1,4,5-trisphosphate + H2O \rightleftharpoons ''myo''-inos ...
* : inositol-1,4-bisphosphate 1-phosphatase * :
sugar-terminal-phosphatase The enzyme sugar-terminal-phosphatase (EC 3.1.3.58) catalyzes the chemical reaction :D-glucose 6-phosphate + H2O \rightleftharpoons D-glucose + phosphate This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric mon ...
* :
alkylacetylglycerophosphatase The enzyme alkylacetylglycerophosphatase (EC 3.1.3.59) catalyzes the reaction :1-alkyl-2-acetyl-''sn''-glycero-3-phosphate + H2O \rightleftharpoons 1-alkyl-2-acetyl-''sn''-glycerol + phosphate This enzyme belongs to the family of hydrolases, spec ...
* : phospho''enol''pyruvate phosphatase * EC 3.1.3.61: deleted, as its existence has not been established * :
multiple inositol-polyphosphate phosphatase The enzyme multiple inositol-polyphosphate phosphatase (EC 3.1.3.62) catalysis, catalyzes the reaction :''myo''-inositol hexakisphosphate + H2O \rightleftharpoons ''myo''-inositol pentakisphosphate (mixed isomers) + phosphate This enzyme belongs ...
* : 2-carboxy-D-arabinitol-1-phosphatase * :
phosphatidylinositol-3-phosphatase The enzyme phosphatidylinositol-3-phosphatase (EC 3.1.3.64) catalyzes the reaction :1-phosphatidyl-1D-''myo''-inositol 3-phosphate + H2O \rightleftharpoons 1-phosphatidyl-1D-''myo''-inositol + phosphate This enzyme belongs to the family of hydro ...
* EC 3.1.3.65: Now included with , phosphatidylinositol-3-phosphatase * : phosphatidylinositol-3,4-bisphosphate 4-phosphatase * :
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase The enzyme phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase (EC 3.1.3.67) catalyzes the chemical reaction :1-phosphatidyl-1D-''myo''-inositol 3,4,5-trisphosphate + H2O = 1-phosphatidyl-1D-''myo''inositol 4,5-bisphosphate + phosphate This e ...
* :
2-deoxyglucose-6-phosphatase The enzyme 2-deoxyglucose-6-phosphatase (EC 3.1.3.68) catalyzes the reaction :2-deoxy-D-glucose 6-phosphate + H2O \rightleftharpoons 2-deoxy-D-glucose + phosphate This enzyme belongs to the family of hydrolases, specifically those acting on phos ...
* :
glucosylglycerol 3-phosphatase The enzyme glucosylglycerol 3-phosphatase (EC 3.1.3.69) catalyzes the reaction :2-''O''-(α-Dglucosyl)-''sn''-glycerol-3-phosphate + H2O = 2-''O''-(α-D-glucopyranosyl)glycerol + phosphate This enzyme belongs to the family of hydrolases, specific ...
* : mannosyl-3-phosphoglycerate phosphatase * :
2-phosphosulfolactate phosphatase The enzyme 2-phosphosulfolactate phosphatase (EC 3.1.3.71) catalyzes the reaction :(2''R'')-2-phospho-3-sulfolactate + H2O \rightleftharpoons (2''R'')-3-sulfolactate + phosphate This enzyme belongs to the family of hydrolases, specifically those ...
* :
5-phytase The enzyme 5-phytase (EC 3.1.3.72) catalyzes the reaction :''myo''-inositol hexakisphosphate + H2O = 1L-''myo''-inositol 1,2,3,4,6-pentakisphosphate + phosphate ''myo''-Inositol hexakisphosphate is also known as phytic acid. These enzymes belon ...
* : adenosylcobalamin/α-ribazole phosphatase * :
pyridoxal phosphatase The enzyme pyridoxal phosphatase (EC 3.1.3.74) catalysis, catalyzes the reaction :pyridoxal 5′-phosphate + H2O \rightleftharpoons pyridoxal + phosphate This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric est ...
* : phosphoethanolamine/phosphocholine phosphatase * : lipid-phosphate phosphatase * :
acireductone synthase Acireductone synthase (EC number 3.1.3.77, E1, E-1 enolase-phosphatase) is an enzyme with List of enzymes, systematic name 5-(methylsulfanyl)-2,3-dioxopentyl-phosphate phosphohydrolase (isomerizing). It catalysis, catalyses the following reaction: ...
* : phosphatidylinositol-4,5-bisphosphate 4-phosphatase * :
mannosylfructose-phosphate phosphatase Mannosylfructose-phosphate phosphatase (EC 3.1.3.79, mannosylfructose-6-phosphate phosphatase, MFPP) is an enzyme with systematic name ''β-D-ructofuranosyl-α-D-mannopyranoside-6F-phosphate phosphohydrolase''. This enzyme catalyses the following ...
* :
2,3-bisphosphoglycerate 3-phosphatase 2,3-Bisphosphoglycerate 3-phosphatase (EC 3.1.3.80, MIPP1, 2,3-BPG 3-phosphatase) is an enzyme with systematic name 2,3-bisphospho-D-glycerate 3-phosphohydrolase. This enzyme catalyses the following reaction: : 2,3-bisphospho-D-glycerate + H2O \ ...
* EC 3.1.3.81: Transferred entry, now , diacylglycerol diphosphate phosphatase * : D-''glycero''-β-D-''manno''-heptose 1,7-bisphosphate 7-phosphatase * : D-''glycero''-α-D-''manno''-heptose 1,7-bisphosphate 7-phosphatase * : ADP-ribose 1′′-phosphate phosphatase * :
glucosyl-3-phosphoglycerate phosphatase Glucosyl-3-phosphoglycerate phosphatase (EC 3.1.3.85, GpgP protein) is an enzyme with systematic name α-D-glucosyl-3-phospho-D-glycerate phosphohydrolase. This enzyme catalyses the following chemical reaction : 2-''O''-(α-D-glucopyranosyl)-3-ph ...
* : phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase * :
2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase (EC 3.1.3.87, HK-MTPenyl-1-''P'' phosphatase, MtnX, YkrX) is an enzyme with systematic name 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate phosphohydrolase. This enzyme catalyses ...
* : 5′′-phosphoribostamycin phosphatase : * No Wikipedia article


EC 3.1.4: Phosphoric Diester Hydrolases

* :
phosphodiesterase I Phosphodiesterase 1, PDE1, EC 3.1.4.1, systematic name oligonucleotide 5-nucleotidohydrolase) is a phosphodiesterase enzyme also known as calcium- and calmodulin-dependent phosphodiesterase. It is one of the 11 families of phosphodiesterase (PDE1- ...
* :
glycerophosphocholine phosphodiesterase The enzyme glycerophosphocholine phosphodiesterase (EC 3.1.4.2) catalyzes the reaction :''sn''-glycero-3-phosphocholine + H2O \rightleftharpoons choline + ''sn''-glycerol 3-phosphate This enzyme belongs to the family of hydrolases, specifically t ...
* :
lecithinase C Phospholipase C (EC 3.1.4.3, lipophosphodiesterase I, ''Clostridium welchii'' α-toxin, ''Clostridium oedematiens'' β- and γ-toxins, lipophosphodiesterase C, phosphatidase C, heat-labile hemolysin, α-toxin) is an enzyme with systematic name pho ...
* :
phospholipase D Phospholipase D (PLD) (EC 3.1.4.4; also known as lipophosphodiesterase II, lecithinase D, choline phosphatase; systematic name: phosphatidylcholine phosphatidohydrolase) is an anesthetic-sensitive and mechanosensitive enzyme of the phospholipa ...
* EC 3.1.4.5: Now , deoxyribonuclease I * EC 3.1.4.6: Now , deoxyribonuclease II * EC 3.1.4.7: Now , micrococcal nuclease * EC 3.1.4.8: Now , ribonuclease T1 * EC 3.1.4.9: Now , ''Serratia marcescens'' nuclease * EC 3.1.4.10: Now , phosphatidylinositol diacylglycerol-lyase * :
phosphoinositide phospholipase C Phosphoinositide phospholipase C (PLC, EC 3.1.4.11, triphosphoinositide phosphodiesterase, phosphoinositidase C, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase, monophosphatidylinositol phosphodiesterase, phosphatidylinositol phospho ...
* :
sphingomyelin phosphodiesterase Sphingomyelin phosphodiesterase (EC 3.1.4.12, also known as neutral sphingomyelinase, sphingomyelinase, or SMase; systematic name sphingomyelin cholinephosphohydrolase) is a hydrolase enzyme that is involved in sphingolipid metabolism reactions. ...
* :
serine-ethanolaminephosphate phosphodiesterase The enzyme serine-ethanolaminephosphate phosphodiesterase (EC 3.1.4.13) catalyzes the reaction :serine phosphoethanolamine + H2O \rightleftharpoons serine + ethanolamine phosphate This enzyme belongs to the family of hydrolases, specifically thos ...
* : cyl-carrier-proteinphosphodiesterase * : transferred to EC 2.7.7.89, adenylyl- lutamateammonia ligasephosphorylase * : 2′,3′-cyclic-nucleotide 2′-phosphodiesterase * : 3′,5′-cyclic-nucleotide phosphodiesterase * EC 3.1.4.18: Now , spleen exonuclease * EC 3.1.4.19: Now , oligonucleotidase * EC 3.1.4.20: Now , exoribonuclease II * EC 3.1.4.21: Now , ''Aspergillus'' nuclease S1 * EC 3.1.4.22: Now , pancreatic ribonuclease * EC 3.1.4.23: Now , ribonuclease T2 * EC 3.1.4.24: deleted * EC 3.1.4.25: Now , exodeoxyribonuclease I * EC 3.1.4.26: deleted * EC 3.1.4.27: Now , exodeoxyribonuclease III * EC 3.1.4.28: Now , exodeoxyribonuclease (lambda-induced) * EC 3.1.4.29: deleted * EC 3.1.4.30: Now , deoxyribonuclease IV (phage-T4-induced) * EC 3.1.4.31: Now * EC 3.1.4.32: deleted * EC 3.1.4.33: deleted * EC 3.1.4.34: deleted * : 3′,5′-cyclic-GMP phosphodiesterase * EC 3.1.4.36: Now with * : 2′,3′-cyclic-nucleotide 3'-phosphodiesterase * :
glycerophosphocholine cholinephosphodiesterase The enzyme glycerophosphocholine cholinephosphodiesterase (EC 3.1.4.38) is an enzyme that catalyzes the reaction :''sn''-''glycero''-3-phosphocholine + H2O = glycerol + phosphocholine This enzyme belongs to the family of hydrolases, specifically ...
* :
alkylglycerophosphoethanolamine phosphodiesterase The enzyme alkylglycerophosphoethanolamine phosphodiesterase (EC 3.1.4.39) catalyzes the reaction :1-alkyl-''sn''-glycero-3-phosphoethanolamine + H2O \rightleftharpoons 1-alkyl-''sn''-glycerol 3-phosphate + ethanolamine This enzyme belongs to the ...
* : CMP-''N''-acylneuraminate phosphodiesterase * : sphingomyelin phosphodiesterase D * : glycerol-1,2-cyclic-phosphate 2-phosphodiesterase * :
glycerophosphoinositol inositolphosphodiesterase The enzyme glycerophosphoinositol inositolphosphodiesterase (EC 3.1.4.43) is an enzyme that catalyzes the chemical reaction :1-(''sn''-glycero-3-phospho)-1D-''myo''-inositol + H2O \rightleftharpoons glycerol + 1D-''myo''-inositol 1-phosphate This ...
* : glycerophosphoinositol glycerophosphodiesterase * : ''N''-acetylglucosamine-1-phosphodiester α-''N''-acetylglucosaminidase * : glycerophosphodiester phosphodiesterase * EC 3.1.4.47: Now , glycosylphosphatidylinositol diacylglycerol-lyase * : dolichylphosphate-glucose phosphodiesterase * : dolichylphosphate-mannose phosphodiesterase * : glycosylphosphatidylinositol phospholipase D * : glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase * :
cyclic-guanylate-specific phosphodiesterase Cyclic-guanylate-specific phosphodiesterase (EC 3.1.4.52, cyclic bis(3′→5')diguanylate phosphodiesterase, c-di-GMP-specific phosphodiesterase, c-di-GMP phosphodiesterase, phosphodiesterase, phosphodiesterase A1, PDEA1, VieA) is an enzyme with L ...
* : 3′,5′-cyclic-AMP phosphodiesterase * : ''N''-acetylphosphatidylethanolamine-hydrolysing phospholipase D * : phosphoribosyl 1,2-cyclic phosphate phosphodiesterase * * : 7,8-dihydroneopterin 2′,3′-cyclic phosphate phosphodiesterase * : phosphoribosyl 1,2-cyclic phosphate 1,2-diphosphodiesterase * : RNA 2′,3′-cyclic 3′-phosphodiesterase * * : cyclic-di-AMP phosphodiesterase * * : pApA phosphodiesterase * * : cyclic 2,3-diphosphoglycerate hydrolase * : *No Wikipedia article


EC 3.1.5: Triphosphoric Monoester Hydrolases

* :
dGTPase The enzyme dGTPase (EC 3.1.5.1) catalyzes the reaction :dGTP + H2O \rightleftharpoons deoxyguanosine + triphosphate This enzyme belongs to the family of hydrolases, specifically those acting on triphosphoric monoester bonds. The systematic nam ...


EC 3.1.6: Sulfuric Ester Hydrolases

* : arylsulfatase (type I) * :
steryl-sulfatase Steroid sulfatase (STS), or steryl-sulfatase (EC 3.1.6.2), formerly known as arylsulfatase C, is a sulfatase enzyme involved in the metabolism of steroids. It is encoded by the ''STS'' gene. Reactions This enzyme catalyses the following chemic ...
* :
glycosulfatase The enzyme glycosulfatase (EC 3.1.6.3) catalyzes the reaction :D-glucose 6-sulfate + H2O \rightleftharpoons D-glucose + sulfate This enzyme belongs to the family of hydrolases, specifically those acting on sulfuric ester bonds. The systematic na ...
* : ''N''-acetylgalactosamine-6-sulfatase * EC 3.1.6.5: deleted * :
choline-sulfatase The enzyme choline-sulfatase (EC 3.1.6.6) catalyzes the reaction :choline sulfate + H2O \rightleftharpoons choline + sulfate This enzyme belongs to the family of hydrolases, specifically those acting on sulfuric ester bonds. The systematic name ...
* :
cellulose-polysulfatase The enzyme cellulose-polysulfatase (EC 3.1.6.7) catalyzes hydrolysis of the 2- and 3-sulfate groups of the polysulfates of cellulose and charonin. This enzyme belongs to the family of hydrolases, specifically those acting on sulfuric ester bonds. ...
* : cerebroside-sulfatase * :
chondro-4-sulfatase The enzyme chondro-4-sulfatase (EC 3.1.6.9) catalyzes the reaction :4-deoxy-β-D-gluc-4-enuronosyl-(1→3)-''N''-acetyl-D-galactosamine 4-sulfate + H2O \rightleftharpoons 4-deoxy-β-D-gluc-4-enuronosyl-(1→3)-''N''-acetyl-D-galactosamine + sulfat ...
* :
chondro-6-sulfatase The enzyme chondro-6-sulfatase (EC 3.1.6.10) catalyzes the reaction :4-deoxy-β-D-gluc-4-enuronosyl-(1→3)-''N''-acetyl-D-galactosamine 6-sulfate + H2O \rightleftharpoons 4-deoxy-β-D-gluc-4-enuronosyl-(1→3)-''N''-acetyl-D-galactosamine + sulfa ...
* : disulfoglucosamine-6-sulfatase * : ''N''-acetylgalactosamine-6-sulfatase * :
iduronate-2-sulfatase Iduronate 2-sulfatase (EC 3.1.6.13; systematic name L-iduronate-2-sulfate 2-sulfohydrolase) is a sulfatase enzyme associated with Hunter syndrome. It catalyses hydrolysis of the 2-sulfate groups of the L-iduronate 2-sulfate units of dermatan sulfa ...
* : ''N''-acetylglucosamine-6-sulfatase * : ''N''-sulfoglucosamine-3-sulfatase * : monomethyl-sulfatase * : D-lactate-2-sulfatase * :
Glucuronate-2-sulfatase In enzymology, a glucuronate-2-sulfatase () is an enzyme that catalyzes the chemical reaction of cleaving off the 2-sulfate groups of the 2-O-sulfo-D-glucuronate residues of chondroitin sulfate, heparin and heparitin sulfate. This enzyme belongs ...
* : (''R'')-specific secondary-alkylsulfatase (type III) * * : ''S''-sulfosulfanyl-L-cysteine sulfohydrolase * * : linear primary-alkylsulfatase * * : branched primary-alkylsulfatase * : *No Wikipedia article


EC 3.1.7: Diphosphoric Monoester Hydrolases

* :
prenyl-diphosphatase The enzyme prenyl-diphosphatase (EC 3.1.7.1) catalysis, catalyzes the reaction :prenyl diphosphate + H2O \rightleftharpoons prenol + diphosphate This enzyme belongs to the family of hydrolases, specifically those acting on diphosphoric ester, mon ...
* : guanosine-3′,5′-bis(diphosphate) 3′-diphosphatase * :
monoterpenyl-diphosphatase The enzyme monoterpenyl-diphosphatase (EC 3.1.7.3) catalyzes the reaction :a monoterpenyl diphosphate + H2O \rightleftharpoons a monoterpenol + diphosphate This enzyme belongs to the family of hydrolases, specifically those acting on diphosphoric ...
* EC 3.1.7.4: Now recognized as two enzymes , copal-8-ol diphosphate synthase and , sclareol synthase * :
geranylgeranyl diphosphate diphosphatase Geranylgeranyl diphosphate diphosphatase (ES 3.1.7.5, geranylgeranyl diphosphate phosphatase) is an enzyme with systematic name geranyl-diphosphate diphosphohydrolase. This enzyme catalyses the following chemical reaction : geranylgeranyl diphos ...
* :
farnesyl diphosphatase Farnesyl diphosphatase (EC 3.1.7.6, FPP phosphatase) is an enzyme with systematic name (2''E'',6''E'')-farnesyl-diphosphate diphosphohydrolase. It catalyses the reaction : (2''E'',6''E'')-farnesyl diphosphate + H2O \rightleftharpoons (2''E'',6''E ...
* EC 3.1.7.7: Now , (–)-drimenol synthase * EC 3.1.7.8: Now known to be a partial activity of , adenosine tuberculosinyltransferase. * EC 3.1.7.9: Now known to be a partial activity of , adenosine tuberculosinyltransferase * : (13''E'')-labda-7,13-dien-15-ol synthase * :
geranyl diphosphate diphosphatase Geranyl diphosphate diphosphatase (EC 3.1.7.11, geraniol synthase', geranyl pyrophosphate pyrophosphatase) is an enzyme with systematic name geranyl-diphosphate diphosphohydrolase. This enzyme catalyses the following chemical reaction : geranyl d ...
* : (+)-kolavelool synthase * : *No Wikipedia article


EC 3.1.8: Phosphoric Triester Hydrolases

* :
aryldialkylphosphatase Aryldialkylphosphatase (EC 3.1.8.1, also known as phosphotriesterase, organophosphate hydrolase, parathion hydrolase, paraoxonase, and parathion aryl esterase; systematic name aryltriphosphate dialkylphosphohydrolase) is a Metalloprotein, metalloen ...
* :
diisopropyl-fluorophosphatase The enzyme diisopropyl-fluorophosphatase (EC 3.1.8.2) catalyzes the reaction :diisopropyl fluorophosphate + H2O \rightleftharpoons diisopropyl phosphate + fluoride This enzyme belongs to the family of hydrolases, specifically those acting on ...


EC 3.1.11: Exodeoxyribonucleases Producing 5'-Phosphomonoesters

* : exodeoxyribonuclease I * :
exodeoxyribonuclease III Exodeoxyribonuclease III (EC 3.1.11.2, ''Escherichia coli'' exonuclease III, ''E. coli'' exonuclease III, endoribonuclease III) is an enzyme that catalyses the following reaction : Exonucleolytic cleavage in the 3′- to 5′-direction to yield n ...
* :
exodeoxyribonuclease (lambda-induced) Exodeoxyribonuclease (lambda-induced) (EC 3.1.11.3, lambda exonuclease, phage lambda-induced exonuclease, ''Escherichia coli'' exonuclease IV, ''E. coli'' exonuclease IV, exodeoxyribonuclease IV, exonuclease IV) is an exonuclease. This enzyme cata ...
* : exodeoxyribonuclease (phage SP3-induced) * : exodeoxyribonuclease V * :
exodeoxyribonuclease VII The enzyme exodeoxyribonuclease VII (EC 3.1.11.6, ''Escherichia coli'' exonuclease VII, ''E. coli'' exonuclease VII, endodeoxyribonuclease VII, exodeoxyribonuclease VII) is a bacterial exonuclease enzyme. It is composed of two nonidentical subunit ...
* EC 3.1.11.7: Now , adenosine-5′-diphospho-5′- NAdiphosphatase * EC 3.1.11.8: Now , guanosine-5′-diphospho-5′- NAdiphosphatase


EC 3.1.13: Exoribonucleases Producing 5'-Phosphomonoesters

* :
exoribonuclease II Exoribonuclease II (, ''ribonuclease II'', ''ribonuclease Q'', ''BN ribonuclease'', ''Escherichia coli exo-RNase II'', ''RNase II'', ''exoribonuclease (misleading)'', ''5'-exoribonuclease'') is an enzyme. This enzyme catalyses the following chemic ...
* :
exoribonuclease H Exoribonuclease H () is an enzyme. This enzyme catalyses the following chemical reaction : 3'-end directed exonucleolytic cleavage of viral RNA-DNA hybrid This is a secondary reaction to the RNA 5'-end directed cleavage 13-19 nucleotide Nu ...
* :
oligonucleotidase Oligonucleotidase (, ''oligoribonuclease'') is an exoribonuclease derived from ''Flammulina velutipes''. This enzyme catalyses the following chemical reaction A chemical reaction is a process that leads to the chemistry, chemical transformat ...
* :
poly(A)-specific ribonuclease Poly(A)-specific ribonuclease (PARN), also known as polyadenylate-specific ribonuclease or deadenylating nuclease (DAN), is an enzyme that in humans is encoded by the ''PARN'' gene In biology, the word gene has two meanings. The Mendelian ...
* :
ribonuclease D RNase D is one of the seven exoribonucleases identified in ''E. coli''. It is a 3'-5' exoribonuclease which has been shown to be involved in the 3' processing of various stable RNA molecules. RNase D has homologues in many other organisms like e ...


EC 3.1.14: Exoribonucleases Producing 3'-Phosphomonoesters

* :
yeast ribonuclease Yeast ribonuclease () is an enzyme. This enzyme catalyses the following chemical reaction A chemical reaction is a process that leads to the chemistry, chemical transformation of one set of chemical substances to another. When chemical reactio ...


EC 3.1.15: Exonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing 5'-Phosphomonoesters

* :
venom exonuclease Venom exonuclease (, ''venom phosphodiesterase'') is an enzyme. This enzyme catalyses the following chemical reaction A chemical reaction is a process that leads to the chemistry, chemical transformation of one set of chemical substances to an ...


EC 3.1.16: Exonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing 3'-Phosphomonoesters

* :
spleen exonuclease Spleen exonuclease (, ''3'-exonuclease'', ''spleen phosphodiesterase'', ''3'-nucleotide phosphodiesterase'', ''phosphodiesterase II'') is an enzyme. This enzyme catalyses the following chemical reaction Exonucleolytic cleavage in the 5'- to 3'-d ...


EC 3.1.21: Endodeoxyribonucleases Producing 5'-Phosphomonoesters

* :
deoxyribonuclease I Deoxyribonuclease I (usually called DNase I), is an endonuclease of the DNase family coded by the human gene DNASE1. DNase I is a nuclease that cleaves DNA preferentially at phosphodiester linkages adjacent to a pyrimidine nucleotide, yielding 5 ...
* :
deoxyribonuclease IV Deoxyribonuclease IV (phage-T4-induced) (, ''endodeoxyribonuclease IV (phage T4-induced)'', ''E. coli endonuclease IV'', ''endodeoxyribonuclease'', ''redoxyendonuclease'', ''deoxriboendonuclease'', ''Escherichia coli endonuclease II'', ''endonucle ...
* :
type I site-specific deoxyribonuclease Type I site-specific deoxyribonuclease (, ''type I restriction enzyme'', ''deoxyribonuclease (ATP- and S-adenosyl-L-methionine-dependent)'', ''restriction-modification system'', ''deoxyribonuclease (adenosine triphosphate-hydrolyzing)'', ''adenosin ...
* :
type II site-specific deoxyribonuclease Type II site-specific deoxyribonuclease (, ''type II restriction enzyme'') is an enzyme. This enzyme catalyses the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates. See also * Restriction en ...
* :
type III site-specific deoxyribonuclease Type III site-specific deoxyribonuclease (, ''type III restriction enzyme'', ''restriction-modification system'') is an enzyme. This enzyme catalyses the following chemical reaction : Endonucleolytic cleavage of DNA to give specific double-strand ...
* :
CC-preferring endodeoxyribonuclease CC-preferring endodeoxyribonuclease (, ''Streptomyces glaucescens exocytoplasmic dodeoxyribonuclease'') is an enzyme. This enzyme catalyses the following chemical reaction A chemical reaction is a process that leads to the chemistry, chemical ...
* :
deoxyribonuclease V Deoxyribonuclease V (, ''endodeoxyribonuclease V'', ''DNase V'', ''Escherichia coli endodeoxyribonuclease V'') is an enzyme. This enzyme catalyses the following chemical reaction : Endonucleolytic cleavage at apurinic or apyrimidinic sites to p ...
* : T4 deoxyribonuclease II * * : T4 deoxyribonuclease IV * * : crossover junction endodeoxyribonuclease * : *No Wikipedia article


EC 3.1.22: Endodeoxyribonucleases Producing 3'-Phosphomonoesters

* : deoxyribonuclease II * : Aspergillus deoxyribonuclease K1 * EC 3.1.22.3: now * : crossover junction endodeoxyribonuclease * :
deoxyribonuclease X Deoxyribonuclease X (, ''Escherichia coli endodeoxyribonuclease'', ''Escherichia coli endodeoxyribonuclease X'') is an enzyme. This enzyme catalyses the following chemical reaction : Endonucleolytic cleavage of supercoiled DNA supercoiling ...


EC 3.1.23: and EC 3.1.24 now EC 3.1.21.3, EC 3.1.21.4 and EC 3.1.21.5

Deleted sub-subclasses.


EC 3.1.25: Site-Specific Endodeoxyribonucleases Specific for Altered Bases

* :
deoxyribonuclease (pyrimidine dimer) Deoxyribonuclease (pyrimidine dimer) (, ''endodeoxyribonuclease (pyrimidine dimer)'', ''bacteriophage T4 endodeoxyribonuclease V'', ''T4 endonuclease V'') is an enzyme. This enzyme catalyses the following chemical reaction: : Endonucleolytic clea ...
* EC 3.1.25.2: Now , DNA-(apurinic or apyrimidinic site) lyase


EC 3.1.26: Endoribonucleases Producing 5'-Phosphomonoesters

* : ''Physarum polycephalum'' ribonuclease * : ribonuclease α * :
ribonuclease III Ribonuclease III (RNase III or RNase C) (BREND3.1.26.3 is a type of ribonuclease that recognizes dsRNA and cleaves it at specific targeted locations to transform them into mature RNAs. These enzymes are a group of endoribonucleases that are char ...
* :
ribonuclease H Ribonuclease H (abbreviated RNase H or RNH) is a family of non-sequence-specific endonuclease enzymes that catalyze the cleavage of RNA in an RNA/DNA substrate via a hydrolytic mechanism. Members of the RNase H family can be found in nearly al ...
* : ribonuclease P * :
ribonuclease IV Ribonuclease IV (, ''endoribonuclease IV'', ''poly(A)-specific ribonuclease'') is an enzyme. This enzyme catalyses the following chemical reaction : Endonucleolytic cleavage of poly(A) to fragments terminated by 3'-hydroxy and 5'-phosphate groups ...
* :
ribonuclease P4 Ribonuclease P4 () is an enzyme. This enzyme catalyses the following chemical reaction : Endonucleolytic cleavage of RNA Ribonucleic acid (RNA) is a polymeric molecule that is essential for most biological functions, either by performing th ...
* : ribonuclease M5 * :
ribonuclease (poly-(U)-specific) Ribonuclease (poly-(U)-specific) (, ''ribonuclease (uracil-specific)'', ''uracil-specific endoribonuclease'', ''uracil-specific RNase'') is an enzyme. This enzyme catalyses the following chemical reaction : Endonucleolytic cleavage of poly(U) to ...
* :
ribonuclease IX Ribonuclease IX (, ''poly(U)- and poly(C)-specific endoribonuclease'') is an enzyme. This enzyme catalyses the following chemical reaction : Endonucleolytic cleavage of poly(U) or poly(C) to fragments terminated by 3'- hydroxy and 5'-phosphate gr ...
* : tRNase Z * : ribonuclease E * : retroviral ribonuclease H


EC 3.1.27: Endoribonucleases Producing 3'-Phosphomonoesters

* EC 3.1.27.1: Now , ribonuclease T2, since the primary reaction is that of a lyase * EC 3.1.27.2: Now , ''Bacillus subtilis'' ribonuclease, since the reaction catalysed is that of a lyase * EC 3.1.27.3: Now , ribonuclease T1, since the primary reaction is that of a lyase * EC 3.1.27.4: Now , ribonuclease U2, since the primary reaction is that of a lyase * EC 3.1.27.5: Now , pancreatic ribonuclease. * EC 3.1.27.6: Now , ''Enterobacter'' ribonuclease, since the primary reaction is that of a lyase * :
ribonuclease F Ribonuclease F (, ''ribonuclease F (E. coli)'') is an enzyme. This enzyme catalyses the following chemical reaction : Endonucleolytic cleavage of RNA precursor into two, leaving 5'- hydroxy and 3'-phosphate Phosphates are the naturally occur ...
* :
ribonuclease V Ribonuclease V (, ''endoribonuclease V'') is an enzyme. This enzyme catalyses the following chemical reaction : Hydrolysis of poly(A), forming oligoribonucleotides and ultimately 3'-AMP This enzyme also hydrolyse Hydrolysis (; ) is any c ...
* EC 3.1.27.9: Now , tRNA-intron lyase * EC 3.1.27.10: Now , ribotoxin,


EC 3.1.30: Endoribonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing 5'-Phosphomonoesters

* : ''Aspergillus'' nuclease S1 * : ''Serratia marcescens'' nuclease


EC 3.1.31: Endoribonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing 3'-Phosphomonoesters

* :
micrococcal nuclease Micrococcal nuclease (, ''S7 Nuclease'', ''MNase'', ''spleen endonuclease'', ''thermonuclease'', ''nuclease T'', ''micrococcal endonuclease'', ''nuclease T, ''staphylococcal nuclease'', ''spleen phosphodiesterase'', ''Staphylococcus aureus nucle ...


EC 3.2: Glycosylases


EC 3.2.1:

Glycosidase In biochemistry, glycoside hydrolases (also called glycosidases or glycosyl hydrolases) are a class of enzymes which catalyze the hydrolysis of glycosidic bonds in complex sugars. They are extremely common enzymes, with roles in nature inclu ...
s, i.e. enzymes hydrolysing ''O''- and ''S''-glycosyl compounds

* : α-amylase * : β-amylase * : glucan 1,4-α-glucosidase * :
cellulase Cellulase (; systematic name 4-β-D-glucan 4-glucanohydrolase) is any of several enzymes produced chiefly by fungi, bacteria, and protozoans that catalyze cellulolysis, the decomposition of cellulose and of some related polysaccharides: : Endo ...
* : deleted * : endo-1,3(4)-β-glucanase * :
inulinase Inulinase ( and , inulase, endoinulinase, endo-inulinase, exoinulinase, 2,1-β-D-fructan fructanohydrolase) is an enzyme with systematic name 1-β-D-fructan fructanohydrolase. It catalyses the reaction: : Endohydrolysis of (2→1)-β-D-fructos ...
* : endo-1,4-β-xylanase * : deleted * : oligo-1,6-glucosidase * : dextranase * : Now included with ,
cyclomaltodextrinase The enzyme cyclomaltodextrinase () catalyzes the chemical reaction :cyclomaltodextrin + H2O \rightleftharpoons linear maltodextrin It belongs to the family of hydrolases, specifically those glycosidases that hydrolyse ''O''- and ''S''-glycosyl c ...
* : Now included with ,
cyclomaltodextrinase The enzyme cyclomaltodextrinase () catalyzes the chemical reaction :cyclomaltodextrin + H2O \rightleftharpoons linear maltodextrin It belongs to the family of hydrolases, specifically those glycosidases that hydrolyse ''O''- and ''S''-glycosyl c ...
* :
chitinase Chitinases (, chitodextrinase, 1,4-β-poly-N-acetylglucosaminidase, poly-β-glucosaminidase, β-1,4-poly-N-acetyl glucosamidinase, poly ,4-(N-acetyl-β-D-glucosaminide)glycanohydrolase, (1→4)-2-acetamido-2-deoxy-β-D-glucan glycanohydrola ...
* :
polygalacturonase Endo-polygalacturonase (, pectin depolymerase, pectolase, pectin hydrolase, and poly-α-1,4-galacturonide glycanohydrolase; systematic name (1→4)-α-D-galacturonan glycanohydrolase (endo-cleaving)) is an enzyme that hydrolyzes the α-1,4 glycos ...
* : deleted * :
lysozyme Lysozyme (, muramidase, ''N''-acetylmuramide glycanhydrolase; systematic name peptidoglycan ''N''-acetylmuramoylhydrolase) is an antimicrobial enzyme produced by animals that forms part of the innate immune system. It is a glycoside hydrolase ...
* : exo-α-sialidase * : deleted * :
α-glucosidase In biochemistry, glycoside hydrolases (also called glycosidases or glycosyl hydrolases) are a class of enzymes which catalyze the hydrolysis of glycosidic bonds in complex sugars. They are extremely common enzymes, with roles in nature includi ...
* : β-glucosidase * : α-galactosidase * :
β-galactosidase β-Galactosidase (EC 3.2.1.23, beta-gal or β-gal; systematic name β-D-galactoside galactohydrolase) is a glycoside hydrolase enzyme that catalyzes hydrolysis of terminal non-reducing β-D-galactose residues in β-D-galactosides. (This enzym ...
* : α-mannosidase * : β-mannosidase * : β-fructofuranosidase (
invertase β-Fructofuranosidase is an enzyme that catalyzes the hydrolysis (breakdown) of the table sugar sucrose into fructose and glucose. Sucrose is a fructoside. Alternative names for β-fructofuranosidase include invertase, saccharase, glucosucrase ...
) * : deleted * : α,α-trehalase * : Now included with , β-''N''-acetylhexosaminidase * : Now included with , β-''N''-acetylhexosaminidase * : β-glucuronidase * : endo-1,3-β-xylanase * : amylo-α-1,6-glucosidase * : Now included with ,
hyaluronoglucosaminidase Hyaluronidases are a family of enzymes that catalyse the degradation of hyaluronic acid. Karl Meyer classified these enzymes in 1971, into three distinct groups, a scheme based on the enzyme reaction products. The three main types of hyaluronid ...
* :
hyaluronoglucosaminidase Hyaluronidases are a family of enzymes that catalyse the degradation of hyaluronic acid. Karl Meyer classified these enzymes in 1971, into three distinct groups, a scheme based on the enzyme reaction products. The three main types of hyaluronid ...
* : hyaluronoglucuronidase * : xylan 1,4-β-xylosidase * : β-D-fucosidase * : glucan endo-1,3-β-D-glucosidase * : α-L-rhamnosidase * :
pullulanase Pullulanase (, ''limit dextrinase'', ''amylopectin 6-glucanohydrolase'', ''bacterial debranching enzyme'', ''debranching enzyme'', ''α-dextrin endo-1,6-α-glucosidase'', ''R-enzyme'', ''pullulan α-1,6-glucanohydrolase'') is a specific kind of g ...
* : GDP-glucosidase * : β-L-rhamnosidase * : Now , endo-(13)-fucoidanase and , endo-(14)-fucoidanase * :
glucosylceramidase In enzymology, a glucosylceramidase () is an enzyme that catalysis, catalyzes the chemical reaction :D-glucosyl-N-acylsphingosine + H2O \rightleftharpoons D-glucose + N-acylsphingosine Thus, the two substrate (biochemistry), substrates of this e ...
* : galactosylceramidase * : Now known to be catalyzed by , α-galactosidase * :
sucrose α-glucosidase Sucrose α-glucosidase (, ''sucrose α-glucohydrolase'', ''sucrase'', ''sucrase-isomaltase'', ''sucrose.α.-glucohydrolase'', ''intestinal sucrase'', ''sucrase(invertase)'') is an enzyme with List of enzymes, systematic name ''sucrose-α-D-glucohyd ...
* : α-''N''-acetylgalactosaminidase * : α-''N''-acetylglucosaminidase * : α-L-fucosidase * : β-''N''-acetylhexosaminidase * : β-''N''-acetylgalactosaminidase * :
cyclomaltodextrinase The enzyme cyclomaltodextrinase () catalyzes the chemical reaction :cyclomaltodextrin + H2O \rightleftharpoons linear maltodextrin It belongs to the family of hydrolases, specifically those glycosidases that hydrolyse ''O''- and ''S''-glycosyl c ...
* : non-reducing end α-L-arabinofuranosidase * : glucuronosyl-disulfoglucosamine glucuronidase * :
isopullulanase The enzyme isopullulanase () has systematic name ''pullulan 4-glucanohydrolase (isopanose-forming)'', and catalyses the hydrolysis of pullulan to isopanose (6-α-maltosylglucose). It has no activity on starch Starch or amylum is a polymeric ...
* : glucan 1,3-β-glucosidase * : glucan endo-1,3-α-glucosidase * : glucan 1,4-α-maltotetraohydrolase * :
mycodextranase Mycodextranase (, ''1,3-1,4-α-D-glucan 4-glucanohydrolase'') is an enzyme with systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or col ...
* : glycosylceramidase * : 1,2-α-L-fucosidase * : 2,6-β-fructan 6-levanbiohydrolase * :
levanase Levanase (, ''levan hydrolase'', ''2,6-β-D-fructan fructanohydrolase'') is an enzyme with systematic name ''(2→6)-β-D-fructan fructanohydrolase''. This enzyme catalyses the following chemical reaction : Random hydrolysis Hydrolysis (; ) ...
* : Deleted entry: The activity is covered by , α-L-rhamnosidase * : galacturan 1,4-α-galacturonidase * :
isoamylase Isoamylase (, ''debranching enzyme'', ''glycogen α-1,6-glucanohydrolase'') is an enzyme with systematic name ''glycogen 6-α-D-glucanohydrolase''. It catalyses the hydrolysis of (1→6)-α-D-glucosidic branch linkages in glycogen, amylopectin an ...
* : Now included with ,
pullulanase Pullulanase (, ''limit dextrinase'', ''amylopectin 6-glucanohydrolase'', ''bacterial debranching enzyme'', ''debranching enzyme'', ''α-dextrin endo-1,6-α-glucosidase'', ''R-enzyme'', ''pullulan α-1,6-glucanohydrolase'') is a specific kind of g ...
* : glucan 1,6-α-glucosidase * : glucan endo-1,2-β-glucosidase * : xylan 1,3-β-xylosidase * :
licheninase Lichenase (, ''licheninase'', ''β-(1→4)-D-glucan 4-glucanohydrolase'', ''1,3, 1,4-β-glucan endohydrolase'', ''1,3, 1,4-β-glucan 4-glucanohydrolase'', ''1,3-1,4-β-D-glucan 4-glucanohydrolase'') is an enzyme with systematic name ''(1→3)-( ...
* : glucan 1,4-β-glucosidase * : glucan endo-1,6-β-glucosidase * : L-iduronidase * : mannan 1,2-(1,3)-α-mannosidase * : mannan endo-1,4-β-mannosidase * : Now included with , non-reducing end α-L-arabinofuranosidase * :
fructan β-fructosidase Fructan β-fructosidase (, ''exo-β-D-fructosidase'', ''exo-β-fructosidase'', ''polysaccharide β-fructofuranosidase'', ''fructan exohydrolase'') is an enzyme with systematic name ''β-D-fructan fructohydrolase''. It catalyses the hydrolysis of t ...
* : β-agarase * : exo-poly-α-digalacturonosidas * : κ-carrageenase * : glucan 1,3-α-glucosidase * : 6-phospho-β-galactosidase * : 6-phospho-β-glucosidase * : capsular-polysaccharide endo-1,3-α-galactosidase * : non-reducing end β-L-arabinopyranosidase * : arabinogalactan endo-β-1,4-galactanase * : Deleted, not sufficiently characterised. * : cellulose 1,4-β-cellobiosidase (non-reducing end) * : peptidoglycan β-''N''-acetylmuramidase * : α,α-phosphotrehalase * : glucan 1,6-α-isomaltosidase * : dextran 1,6-α-isomaltotriosidase * : mannosyl-glycoprotein endo-β-''N''-acetylglucosaminidase * : endo-α-''N''-acetylgalactosaminidase * : glucan 1,4-α-maltohexaosidase * : arabinan endo-1,5-α-L-arabinanase * : mannan 1,4-mannobiosidase * : mannan endo-1,6-α-mannosidase * : blood-group-substance endo-1,4-β-galactosidase * : keratan-sulfate endo-1,4-β-galactosidase * : steryl-β-glucosidase * : 3α(''S'')-strictosidine β-glucosidase * :
mannosyl-oligosaccharide glucosidase Mannosyl-oligosaccharide glucosidase (MOGS) (, ''processing α-glucosidase I,'' ''Glc3Man9NAc2 oligosaccharide glucosidase'', ''trimming glucosidase I, GCS1'') is an enzyme with systematic name ''mannosyl-oligosaccharide glucohydrolase''. MOGS is ...
* :
protein-glucosylgalactosylhydroxylysine glucosidase The enzyme protein-glucosylgalactosylhydroxylysine glucosidase () catalyzes the following chemical reaction: : ollagen(5''R'')-5-''O''- ±-D-glucosyl-(1→2)-β-D-galactosyl5-hydroxy-L-lysine + H2O = D-glucose + ollagen(5''R'')-5-''O''-(β-D-galac ...
* :
lactase Lactase () is an enzyme produced by many organisms and is essential to the complete digestion of whole milk. It breaks down the sugar lactose into its component parts, galactose and glucose. Lactase is found in the brush border of the small ...
* :
endogalactosaminidase Endogalactosaminidase () is an enzyme with systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually ...
* : identical to , endo-α-''N''-acetylgalactosaminidase * : 1,3-α-L-fucosidase * :
2-deoxyglucosidase The enzyme 2-deoxyglucosidase () catalyzes the following chemical reaction :a 2-deoxy-α-D-glucoside + H2O \rightleftharpoons 2-deoxy-D-glucose + an alcohol It belongs to the family of hydrolases, specifically those glycosidases that hydrolyse ' ...
* : mannosyl-oligosaccharide 1,2-α-mannosidase * : mannosyl-oligosaccharide 1,3-1,6-α-mannosidas * : branched-dextran exo-1,2-α-glucosidase * : glucan 1,4-α-maltotriohydrolase * : amygdalin β-glucosidase * : prunasin β-glucosidase * : vicianin β-glucosidase * : oligoxyloglucan β-glycosidase * :
polymannuronate hydrolase Polymannuronate hydrolase (, ''polymannuronic acid polymerase'') is an enzyme with systematic name ''poly(mannuronide) mannuronohydrolase''. It catalyses endohydrolysis of the D-mannuronide linkages of polymannuronate. This enzyme does not act o ...
* : maltose-6′-phosphate glucosidase * :
endoglycosylceramidase The enzyme endoglycosylceramidase () catalyzes the following chemical reaction: :oligoglycosylglucosylceramide + H2O \rightleftharpoons ceramide + oligoglycosylglucose This enzyme belongs to the family of hydrolases, specifically those glycosidas ...
* : 3-deoxy-2-octulosonidase * : raucaffricine β-glucosidase * : coniferin β-glucosidase * : 1,6-α-L-fucosidase * : glycyrrhizin hydrolase * : endo-α-sialidase * : glycoprotein endo-α-1,2-mannosidase * : xylan α-1,2-glucuronosidase * : chitosanase * : glucan 1,4-α-maltohydrolase * :
difructose-anhydride synthase In enzymology, a difructose-anhydride synthase () is an enzyme that catalyzes the chemical reaction :bis-D-fructose 2',1:2,1'-dianhydride + H2O \rightleftharpoons inulobiose Thus, the two substrates of this enzyme are bis-D-fructose 2',1:2,1'-d ...
* : neopullulanase * : glucuronoarabinoxylan endo-1,4-β-xylanase * : mannan exo-1,2-1,6-α-mannosidase * EC 3.2.1.138: Now , anhydrosialidase * : α-glucuronidase * : lacto-''N''-biosidase * : 4-α-D-trehalose trehalohydrolase * :
limit dextrinase Limit dextrinase (, ''R-enzyme'', ''amylopectin-1,6-glucosidase'', ''dextrin alpha-1,6-glucanohydrolase'') is an enzyme with systematic name ''dextrin 6-alpha-glucanohydrolase''. This enzyme catalyses the hydrolysis of (1->6)-alpha-D-glucosidic l ...
* : poly(ADP-ribose) glycohydrolase * :
3-deoxyoctulosonase In enzymology, a 3-deoxyoctulosonase () is an enzyme that catalyzes the chemical reaction :3-deoxyoctulosonyl-lipopolysaccharide + H2O \rightleftharpoons 3-deoxyoctulosonic acid + lipopolysaccharide Thus, the two substrates of this enzyme are ...
* : galactan 1,3-β-galactosidase * : β-galactofuranosidase * :
thioglucosidase Myrosinase (, ''thioglucoside glucohydrolase'', ''sinigrinase'', and ''sinigrase'') is a family of enzymes involved in plant defense against herbivores, specifically the mustard oil bomb. The three-dimensional structure has been elucidated and is ...
* EC 3.2.1.148: The activity is most probably attributable to , ''S''-ribosylhomocysteine lyase * : β-primeverosidase * : oligoxyloglucan reducing-end-specific cellobiohydrolase * : xyloglucan-specific endo-β-1,4-glucanase * : mannosylglycoprotein endo-β-mannosidase * : fructan β-(2,1)-fructosidase * : fructan β-(2,6)-fructosidase * : xyloglucan-specific endo-processive β-1,4-glucanase * : oligosaccharide reducing-end xylanase * : ι-carrageenase * : α-agarase * : α-neoagaro-oligosaccharide hydrolase * EC 3.2.1.160: identical to , xyloglucan-specific exo-β-1,4-glucanase * : β-apiosyl-β-glucosidase * : λ-carrageenase * : 1,6-α-D-mannosidase * : galactan endo-1,6-β-galactosidase * : exo-1,4-β-D-glucosaminidase * :
heparanase Heparanase, also known as HPSE, is an enzyme that acts both at the cell-surface and within the extracellular matrix to degrade polymeric heparan sulfate molecules into shorter chain length oligosaccharides. Synthesis and structure The protei ...
* : baicalin-β-D-glucuronidase * : hesperidin 6-''O''-α-L-rhamnosyl-β-D-glucosidase * : protein ''O''-GlcNAcas * : mannosylglycerate hydrolase * :
rhamnogalacturonan hydrolase Rhamnogalacturonan hydrolase (, ''rhamnogalacturonase A'', ''RGase A'', ''RG-hydrolase'') is an enzyme with List of enzymes, systematic name ''rhamnogalacturonan alpha-D-GalA-(1->2)-alpha-L-Rha hydrolase''. This enzyme catalysis, catalyses the foll ...
* : unsaturated rhamnogalacturonyl hydrolase * :
rhamnogalacturonan galacturonohydrolase Rhamnogalacturonan galacturonohydrolase (, ''RG-galacturonohydrolase'') is an enzyme with systematic name ''rhamnogalacturonan oligosaccharide alpha-D-GalA-(1->2)-alpha-L-Rha galacturonohydrolase''. This enzyme catalyses the following chemical rea ...
* :
rhamnogalacturonan rhamnohydrolase Rhamnogalacturonan rhamnohydrolase (, ''RG-rhamnohydrolase'', ''RG alpha-L-rhamnopyranohydrolase'') is an enzyme with systematic name ''rhamnogalacturonan oligosaccharide alpha-L-Rha-(1->4)-alpha-D-GalA rhamnohydrolase''. This enzyme catalyses the ...
* : β-D-glucopyranosyl abscisate β-glucosidase * : cellulose 1,4-β-cellobiosidase (reducing end) * : α-D-xyloside xylohydrolase * : β-porphyranase * :
gellan tetrasaccharide unsaturated glucuronyl hydrolase Gellan tetrasaccharide unsaturated glucuronyl hydrolase (, ''UGL'', ''unsaturated glucuronyl hydrolase'') is an enzyme with systematic name ''beta-D-4-deoxy-Delta4-GlcAp-(1->4)-beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-beta-D-Glcp beta-D-4-deoxy-Delta ...
* : unsaturated chondroitin disaccharide hydrolase * : galactan endo-β-1,3-galactanase * : 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2''H''-1,4-benzoxazin-2-yl glucoside β-D-glucosidase * : UDP-''N''-acetylglucosamine 2-epimerase (hydrolysing) * : UDP-''N,N''′-diacetylbacillosamine 2-epimerase (hydrolysing) * : non-reducing end β-L-arabinofuranosidase * * : protodioscin 26-''O''-β-D-glucosidase * * : (Ara-f)3-Hyp β-L-arabinobiosidase * * :
avenacosidase Avenacosidase is a glucosidase enzyme found in the oat species Avena. Avenacosidase is known to act against fungal infection. Avenacosidase is a member of the family of enzymes that catalyze the hydrolysis of O and S-glycosyl In organic chemist ...
* * : dioscin glycosidase (diosgenin-forming) * * : dioscin glycosidase (3-''O''-β-D-Glc-diosgenin-forming) * * : ginsenosidase type III * * : ginsenoside Rb1 β-glucosidase * * : ginsenosidase type I * * : ginsenosidase type IV * * : 20-''O''-multi-glycoside ginsenosidase * * : limit dextrin α-1,6-maltotetraose-hydrolase * * : β-1,2-mannosidase * * : α-mannan endo-1,2-α-mannanase * * : sulfoquinovosidase * * : exo-chitinase (non-reducing end) * * : exo-chitinase (reducing end) * * : endo-chitodextinase * * : carboxymethylcellulase * * : 1,3-α-isomaltosidase * * : isomaltose glucohydrolase * * : oleuropein β-glucosidase * * : mannosyl-oligosaccharide α-1,3-glucosidase * * : glucosylglycerate hydrolase * * : endoplasmic reticulum Man9GlcNAc2 1,2-α-mannosidase * * : endoplasmic reticulum Man8GlcNAc2 1,2-α-mannosidase * * : endo-(1→3)-fucoidanase * * : endo-(1→4)-fucoidanase * * : galactan exo-1,6-β-galactobiohydrolase (non-reducing end) * * : exo β-1,2-glucooligosaccharide sophorohydrolase (non-reducing end) * : *No Wikipedia article


EC 3.2.2: Hydrolysing ''N''-Glycosyl Compounds

* : purine nucleosidase * :
inosine nucleosidase In enzymology, an inosine nucleosidase () is an enzyme that catalyzes the chemical reaction :inosine + H2O \rightleftharpoons D-ribose + hypoxanthine Thus, the two substrates of this enzyme are inosine and H2O, whereas its two products are D-r ...
* :
uridine nucleosidase In enzymology, an uridine nucleosidase () is an enzyme that catalyzes the chemical reaction :uridine + H2O \rightleftharpoons D-ribose + uracil Thus, the two substrates of this enzyme are uridine and H2O, whereas its two products are D-ribose ...
* :
AMP nucleosidase In enzymology, an AMP nucleosidase () is an enzyme that catalyzes the chemical reaction :AMP + H2O \rightleftharpoons D-ribose 5-phosphate + adenine Thus, the two substrates of this enzyme are AMP and H2O, whereas its two products are D-ribose ...
* : NAD+ glycohydrolase * : ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase * :
adenosine nucleosidase In enzymology, an adenosine nucleosidase () is an enzyme that catalyzes the chemical reaction :adenosine + H2O \rightleftharpoons D-ribose + adenine Thus, the two substrates of this enzyme are adenosine and H2O, whereas its two products are D- ...
* :
ribosylpyrimidine nucleosidase In enzymology, a ribosylpyrimidine nucleosidase () is an enzyme that catalyzes the chemical reaction :a pyrimidine nucleoside + H2O \rightleftharpoons D-ribose + a pyrimidine base Thus, the two substrates of this enzyme are pyrimidine nucleosid ...
* :
adenosylhomocysteine nucleosidase In enzymology, an adenosylhomocysteine nucleosidase () is an enzyme that catalysis, catalyzes the chemical reaction :S-adenosyl-L-homocysteine + H2O \rightleftharpoons S-(5-deoxy-D-ribos-5-yl)-L-homocysteine + adenine Thus, the two substrate (bio ...
* : pyrimidine-5′-nucleotide nucleosidase * : β-aspartyl-''N''-acetylglucosaminidase * :
inosinate nucleosidase In enzymology, an inosinate nucleosidase () is an enzyme that catalysis, catalyzes the chemical reaction :5'-inosinate + H2O \rightleftharpoons D-ribose 5-phosphate + hypoxanthine Thus, the two substrate (biochemistry), substrates of this enzyme ...
* : 1-methyladenosine nucleosidase * :
NMN nucleosidase In enzymology, a NMN nucleosidase () is an enzyme that catalyzes the chemical reaction :nicotinamide D-ribonucleotide + H2O \rightleftharpoons D-ribose 5-phosphate + nicotinamide Thus, the two substrates of this enzyme are nicotinamide D-ribonu ...
* :
DNA-deoxyinosine glycosylase DNA-deoxyinosine glycosylase (, ''DNA(hypoxanthine) glycohydrolase'', ''deoxyribonucleic acid glycosylase'', ''hypoxanthine-DNA glycosylase'') is an enzyme with systematic name ''DNA-deoxyinosine deoxyribohydrolase''. This enzyme is involved in DNA ...
* :
methylthioadenosine nucleosidase In enzymology, a methylthioadenosine nucleosidase () is an enzyme that catalyzes the chemical reaction :S-methyl-5'-thioadenosine + H2O \rightleftharpoons S-methyl-5-thio-D-ribose + adenine Thus, the two substrates of this enzyme are S-methyl-5 ...
* : deoxyribodipyrimidine endonucleosidase * EC 3.2.2.18: Now included with , peptide-N4-(''N''-acetyl-β-glucosaminyl)asparagine amidase * : ADP-ribosylarginine hydrolase * : DNA-3-methyladenine glycosylase I * : DNA-3-methyladenine glycosylase II, MAG1 * : rRNA N''-glycosylase * : DNA-formamidopyrimidine glycosylase * : ADP-ribosyl- initrogen reductasehydrolase * : ''N''-methyl nucleosidase * :
futalosine hydrolase Futalosine hydrolase (, ''futalosine nucleosidase'', ''MqnB'') is an enzyme with systematic name ''futalosine ribohydrolase''. This enzyme catalyses the following chemical reaction : futalosine + H2O \rightleftharpoons dehypoxanthine futalosine ...
* :
uracil-DNA glycosylase Uracil-DNA glycosylase (also known as UNG or UDG) is an enzyme. Its most important function is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosidic bond and initiating the base-excision repair (BER) pathway ...
* :
double-stranded uracil-DNA glycosylase Double-stranded uracil-DNA glycosylase (, ''Mug'', ''double-strand uracil-DNA glycosylase'', ''Dug'', ''dsUDG'', ''double-stranded DNA specific UDG'', ''dsDNA specific UDG'', ''UdgB'', ''G:T/U mismatch-specific DNA glycosylase'', ''UDG'') is an en ...
* :
thymine-DNA glycosylase G/T mismatch-specific thymine DNA glycosylase is an enzyme that in humans is encoded by the TDG gene. Several bacterial proteins have strong sequence homology with this protein. Function The protein encoded by this gene belongs to the TDG/mug ...
* : aminodeoxyfutalosine nucleosidase * * : adenine glycosylase * : *No Wikipedia article


EC 3.2.3: Hydrolysing ''S''-Glycosyl Compounds

Deleted sub-subclass


EC 3.3: Acting on Ether Bonds


EC 3.3.1: Thioether and trialkylsulfonium hydrolases

* : adenosylhomocysteinase * : ''S''-adenosyl-L-methionine hydrolase (L-homoserine-forming) * EC 3.3.1.3: The activity is most probably attributable to , ''S''-ribosylhomocysteine lyase


EC 3.3.2: Ether Hydrolases

* : isochorismatase * : alkenylglycerophosphocholine hydrolase * EC 3.3.2.3: Now known to comprise two enzymes, microsomal epoxide hydrolase () and soluble epoxide hydrolase () * : ''trans''-epoxysuccinate hydrolase * EC 3.3.2.5: Now included in , lysoplasmalogenase * : leukotriene-A4 hydrolase * : hepoxilin-epoxide hydrolase * : limonene-1,2-epoxide hydrolase * :
microsomal epoxide hydrolase In enzymology, a microsomal epoxide hydrolase (mEH) () is an enzyme that catalysis, catalyzes the hydrolysis reaction between an epoxide and water to form a diol. This enzyme plays a role in the uptake of bile salts within the large intestine. ...
* :
soluble epoxide hydrolase Soluble epoxide hydrolase (sEH) is a bifunctional enzyme that in humans is encoded by the ''EPHX2'' gene. sEH is a member of the epoxide hydrolase family. This enzyme, found in both the cytosol and peroxisomes, binds to specific epoxides and con ...
* : cholesterol-5,6-oxide hydrolase * : oxepin-CoA hydrolase * * : chorismatase * * : 2,4-dinitroanisole ''O''-demethylase * * : ''trans''-2,3-dihydro-3-hydroxyanthranilic acid synthase * : *No Wikipedia article


EC 3.4: Acting on

peptide bond In organic chemistry, a peptide bond is an amide type of covalent chemical bond linking two consecutive alpha-amino acids from C1 (carbon number one) of one alpha-amino acid and N2 (nitrogen number two) of another, along a peptide or protein cha ...
s –
Peptidase A protease (also called a peptidase, proteinase, or proteolytic enzyme) is an enzyme that catalyzes proteolysis, breaking down proteins into smaller polypeptides or single amino acids, and spurring the formation of new protein products. They do ...


EC 3.4.1 α-amino acyl peptide hydrolases (discontinued)

* EC 3.4.1.1: Now , leucyl aminopeptidase * EC 3.4.1.2: Now , membrane alanyl aminopeptidase * EC 3.4.1.3: Now , tripeptide aminopeptidase * EC 3.4.1.4: Now , prolyl aminopeptidase


EC 3.4.2 Peptidyl amino acid hydrolases (discontinued)

* EC 3.4.2.1: Now , carboxypeptidase A * EC 3.4.2.2: Now , carboxypeptidase B * EC 3.4.2.3: Now , Gly-Xaa carboxypeptidase


EC 3.4.3: Dipeptide hydrolases (deleted sub-subclass)

* EC 3.4.3.1: Now , cytosol nonspecific dipeptidase * EC 3.4.3.2: Now , cytosol nonspecific dipeptidase * EC 3.4.3.3: Now , Xaa-His dipeptidase * EC 3.4.3.4: Now , Xaa-methyl-His dipeptidase * EC 3.4.3.5: Now , membrane alanyl aminopeptidase * EC 3.4.3.6: Now , cytosol nonspecific dipeptidase * EC 3.4.3.7: Now , Xaa-Pro dipeptidase


EC 3.4.4 Peptidyl Peptide Hydrolases (discontinued)

* EC 3.4.4.1: Now , pepsin A * EC 3.4.4.2: Now , pepsin B * EC 3.4.4.3: Now , chymosin * EC 3.4.4.4: Now , trypsin * EC 3.4.4.5: Now , chymotrypsin * EC 3.4.4.6: Now , chymotrypsin * EC 3.4.4.7: Now covered by , pancreatic elastase and , leukocyte elastase * EC 3.4.4.8: Now , enteropeptidase * EC 3.4.4.9: Now , dipeptidyl-peptidase I * EC 3.4.4.10: Now , papain * EC 3.4.4.11: Now , chymopapain * EC 3.4.4.12: Now , ficain * EC 3.4.4.13: Now , thrombin * EC 3.4.4.14: Now , plasmin * EC 3.4.4.15: Now , renin * EC 3.4.4.16: Now covered by the microbial serine proteinases (subtilisin), (oryzin), (endopeptidase K), (thermomycolin), (thermitase) and (endopeptidase So) * EC 3.4.4.17: Now covered by the microbial aspartic proteinases (penicillopepsin), (rhizopuspepsin), (endothiapepsin), (mucorpepsin), (candidapepsin), (saccharopepsin), (rhodotorulapepsin), (physarolisin), (acrocylindropepsin), (polyporopepsin) and (pycnoporopepsin) * EC 3.4.4.18: Now , streptopain * EC 3.4.4.19: Now , microbial collagenase * EC 3.4.4.20: Now , clostripain * EC 3.4.4.21: Now (plasma kallikrein) and (tissue kallikrein) * EC 3.4.4.22: Now , gastricsin * EC 3.4.4.23: Now , cathepsin D * EC 3.4.4.24: Now covered by (stem bromelain) and (fruit bromelain) * EC 3.4.4.25: deleted


EC 3.4.11

Aminopeptidase Aminopeptidases are enzymes that catalyze the cleavage of amino acids from the N-terminus (beginning), of proteins or peptides. They are found in many organisms; in the cell, they are found in many organelles, in the cytosol (internal cellular f ...
s

* :
leucyl aminopeptidase Leucyl aminopeptidases (, ''leucine aminopeptidase'', ''LAPs'', ''leucyl peptidase'', ''peptidase S'', ''cytosol aminopeptidase'', ''cathepsin III'', ''L-leucine aminopeptidase'', ''leucinaminopeptidase'', ''leucinamide aminopeptidase'', ''FTBL pr ...
* :
membrane alanyl aminopeptidase Membrane alanyl aminopeptidase () also known as alanyl aminopeptidase (AAP) or aminopeptidase N (AP-N) is an enzyme that in humans is encoded by the ANPEP gene. Function Aminopeptidase N is located in the small-intestinal and renal microvill ...
* : cystinyl aminopeptidase * : tripeptide aminopeptidase * :
prolyl aminopeptidase Prolyl aminopeptidase (, ''proline aminopeptidase'', ''Pro-X aminopeptidase'', ''cytosol aminopeptidase V'', ''proline iminopeptidase'') is an enzyme. This enzyme catalyses the following chemical reaction : Release of N-terminal proline from a p ...
* : aminopeptidase B * :
glutamyl aminopeptidase Glutamyl aminopeptidase (, ''aminopeptidase A'', ''aspartate aminopeptidase'', ''angiotensinase A'', ''glutamyl peptidase'', ''Ca2+-activated glutamate aminopeptidase'', ''membrane aminopeptidase II'', ''antigen BP-1/6C3 of mouse B lymphocytes'', ...
* EC 3.4.11.8: Now
EC 3.4.19.3 Pyroglutamyl-peptidase I (, also known as Pyrrolidonyl peptidase, is an enzyme (a cysteine peptidase) found in bacteria, plants and animals. It can be used to distinguish certain Streptococcal organisms. Other names are ''5-oxoprolyl-peptidase'', ...
, pyroglutamyl-peptidase I * : Xaa-Pro aminopeptidase * : bacterial leucyl aminopeptidase * EC 3.4.11.11: Deleted * EC 3.4.11.12: Deleted * :
Clostridial aminopeptidase Clostridial aminopeptidase (, ''Clostridium histolyticum aminopeptidase'') is an enzyme. This enzyme catalyses the following chemical reaction : Release of any N-terminal amino acid, including proline and hydroxyproline, but no cleavage of Xaa-P ...
* : cytosol alanyl aminopeptidase * :
aminopeptidase Y Aminopeptidase Y (, ''aminopeptidase Co'', ''aminopeptidase (cobalt-activated)'', ''lysyl aminopeptidase'') is an enzyme. This enzyme catalyses the following chemical reaction : Preferentially, release of N-terminal lysine Lysine (symbol Ly ...
* : Xaa-Trp aminopeptidase * :
tryptophanyl aminopeptidase Tryptophanyl aminopeptidase (, ''tryptophan aminopeptidase'', ''L-tryptophan aminopeptidase'') is an enzyme. This enzyme catalyses the following chemical reaction : Preferential release of N-terminal tryptophan Tryptophan (symbol Trp or W) ...
* :
methionyl aminopeptidase Methionyl aminopeptidase (, ''methionine aminopeptidase'', ''peptidase M'', ''L-methionine aminopeptidase'', ''MAP'') is an enzyme. This enzyme catalyses the following chemical reaction : Release of N-terminal amino acids, preferentially methion ...
* : D-stereospecific aminopeptidase * : aminopeptidase Ey * :
aspartyl aminopeptidase Aspartyl aminopeptidase () is an enzyme. This enzyme catalyses the following chemical reaction : Release of an N-terminal aspartate or glutamate from a peptide Peptides are short chains of amino acids linked by peptide bonds. A polypeptide ...
* :
aminopeptidase I Aminopeptidase I (, ''aminopeptidase III'', ''aminopeptidase yscI'', ''leucine aminopeptidase IV'', ''yeast aminopeptidase I'') is an enzyme. This enzyme catalyses the following chemical reaction : Release of an N-terminal amino acid, preferably ...
* :
PepB aminopeptidase PepB aminopeptidase (, ''Salmonella enterica serovar Typhimurium peptidase B'') is an enzyme which catalyses the following chemical reaction: : Release of an N-terminal amino acid, Xaa, from a peptide Peptides are short chains of amino acids ...
* :
aminopeptidase S Aminopeptidase S (, ''Mername-AA022 peptidase'', ''SGAP'', ''aminopeptidase (Streptomyces griseus)'', ''Streptomyces griseus aminopeptidase'', ''S. griseus AP'', ''double-zinc aminopeptidase'') is an enzyme. This enzyme catalyses the following ch ...
* : β-peptidyl aminopeptidase * :
intermediate cleaving peptidase 55 Intermediate cleaving peptidase 55 (, ''Icp55'', ''mitochondrial intermediate cleaving peptidase 55 kDa'') is an enzyme. This enzyme catalyses the following chemical reaction : The enzyme cleaves the Pro36-Pro37 bond of cysteine desulfurase ( E ...


EC 3.4.12 Peptidylamino-acid hydrolases or acylamino-acid hydrolases (deleted sub-subclass)

* EC 3.4.12.1: Now (carboxypeptidase C) and (carboxypeptidase D) * EC 3.4.12.2: Now , carboxypeptidase A * EC 3.4.12.3: Now , carboxypeptidase B * EC 3.4.12.4: Now , lysosomal Pro-Xaa carboxypeptidase * EC 3.4.12.5: Now , ''N''-acetylmuramoyl-L-alanine amidase * EC 3.4.12.6: Now , muramoyl-pentapeptidase carboxypeptidase * EC 3.4.12.7: Now , lysine carboxypeptidase * EC 3.4.12.8: Now , Gly-Xaa carboxypeptidase * EC 3.4.12.9: aspartate carboxypeptidase * EC 3.4.12.10: Now , γ-glutamyl hydrolase * EC 3.4.12.11: Now , alanine carboxypeptidase * EC 3.4.12.12: Now (carboxypeptidase C) and (carboxypeptidase D) * EC 3.4.12.13: γ-glutamylglutamate carboxypeptidase


EC 3.4.13 Dipeptidases

* EC 3.4.13.1: Now , cytosol nonspecific dipeptidase * EC 3.4.13.2: Now , cytosol nonspecific dipeptidase * EC 3.4.13.3: The activity is covered by , cytosol nonspecific dipeptidase and , β-Ala-His dipeptidase * : Xaa-Arg dipeptidase * : Xaa-methyl-His dipeptidase * EC 3.4.13.6: Now , membrane alanyl aminopeptidase * :
Glu-Glu dipeptidase Glu-Glu dipeptidase (, ''alpha-glutamyl-glutamate dipeptidase'', ''glutamylglutamic arylamidase'') is an enzyme. This enzyme catalyses the following chemical reaction : Hydrolysis of the Glu!Glu dipeptide A dipeptide is an organic compound deriv ...
* EC 3.4.13.8: Now , cytosol nonspecific dipeptidase * : Xaa-Pro dipeptidase * EC 3.4.13.10: Now , β-aspartyl-peptidase * EC 3.4.13.11: Now , membrane dipeptidase * : Met-Xaa dipeptidase * EC 3.4.13.13: Now , Xaa-His dipeptidase * EC 3.4.13.14: Deleted * EC 3.4.13.15: Now , cytosol nonspecific dipeptidase * : Deleted * :
non-stereospecific dipeptidase Non-stereospecific dipeptidase (, ''peptidyl-D-amino acid hydrolase'', ''D-(or L-)aminoacyl-dipeptidase'') is an enzyme. This enzyme catalyses the following chemical reaction : Hydrolysis of dipeptides containing either D- or L-amino acids or bot ...
* : cytosol nonspecific dipeptidase * :
membrane dipeptidase Membrane dipeptidase (, ''renal dipeptidase'', ''dehydropeptidase I (DPH I)'', ''dipeptidase'', ''aminodipeptidase'', ''dipeptide hydrolase'', ''dipeptidyl hydrolase'', ''nonspecific dipeptidase'', ''glycosyl-phosphatidylinositol-anchored renal di ...
* : β-Ala-His dipeptidase * : dipeptidase E * : D-Ala-D-Ala dipeptidase * : cysteinylglycine-''S''-conjugate dipeptidase * : *No Wikipedia article


EC 3.4.14 Dipeptidyl peptidases and tripeptidyl peptidases

* :
dipeptidyl-peptidase I Dipeptidyl peptidase I (, ''cathepsin C'', ''dipeptidyl aminopeptidase I'', ''dipeptidyl transferase'', ''dipeptide arylamidase I'', ''DAP I'') is an enzyme. This enzyme catalyses the following chemical reaction : Release of an N-terminal dipepti ...
* : dipeptidyl-peptidase II * EC 3.4.14.3: Now , acylaminoacyl-peptidase * : dipeptidyl-peptidase III * : dipeptidyl-peptidase IV * : dipeptidyl-dipeptidase * EC 3.4.14.7: Deleted * EC 3.4.14.8: Now , tripeptidyl-peptidase II * : tripeptidyl-peptidase I * :
tripeptidyl-peptidase II Tripeptidyl-peptidase 2 is an enzyme that in humans is encoded by the ''TPP2'' gene. Among other things it is heavily implicated in MHC (HLA) class-I processing, as it has both endopeptidase and exopeptidase activity. Clinical significance and g ...
* :
Xaa-Pro dipeptidyl-peptidase Xaa-Pro dipeptidyl-peptidase (, ''X-prolyl dipeptidyl aminopeptidase'', ''PepX'', ''X-prolyl dipeptidyl peptidase'' is an enzyme. It catalyses the following chemical reaction : Hydrolyses Xaa-Pro bonds to release unblocked, N-terminal dipeptides ...
* : Xaa-Xaa-Pro tripeptidyl-peptidase * : γ-D-glutamyl-Llysine dipeptidyl-peptidase * : ycofactocin precursor peptidepeptidase * : *No Wikipedia article


EC 3.4.15

Peptidyl dipeptidase Angiotensin-converting enzyme (), or ACE, is a central component of the renin–angiotensin system (RAS), which controls blood pressure by regulating the volume of fluids in the body. It converts the hormone angiotensin I to the active vasocon ...
s

* : peptidyl-dipeptidase A * EC 3.4.15.2: Now , peptidyl-glycinamidase * EC 3.4.15.3: Now , peptidyl-dipeptidase Dcp * : Peptidyl-dipeptidase B * :
Peptidyl-dipeptidase Dcp Peptidyl-dipeptidase Dcp (, ''dipeptidyl carboxypeptidase (Dcp)'', ''dipeptidyl carboxypeptidase'') is a metalloenzyme found in the cytoplasm of bacterium E. Coli responsible for the C-terminal cleavage of a variety of dipeptides and unprotected la ...
* : cyanophycinase


EC 3.4.16

Serine type carboxypeptidase Serine proteases (or serine endopeptidases) are enzymes that cleave peptide bonds in proteins. Serine serves as the nucleophilic amino acid at the (enzyme's) active site. They are found ubiquitously in both eukaryotes and prokaryotes. Serin ...
s

* EC 3.4.16.1: Transferred entry: serine carboxypeptidase. Now , carboxypeptidase D * : lysosomal Pro-Xaa carboxypeptidase * EC 3.4.16.3: Now included with , carboxypeptidase C * : serine-type D-Ala-D-Ala carboxypeptidase * : carboxypeptidase c, carboxypeptidase C * : carboxypeptidase D


EC 3.4.17 Metallocarboxypeptidases

* : carboxypeptidase A * : carboxypeptidase B * : lysine carboxypeptidase * : Gly-X carboxypeptidase, Gly-Xaa carboxypeptidase * EC 3.4.17.5: Deleted * : alanine carboxypeptidase * EC 3.4.17.7: Now , ''N''-acetylmuramoyl-L-alanine amidase * : muramoylpentapeptide carboxypeptidase * EC 3.4.17.9: Now included with , Gly-Xaa carboxypeptidase * : carboxypeptidase E * : glutamate carboxypeptidase * : carboxypeptidase M * : Muramoyltetrapeptide carboxypeptidase * : Zinc D-Ala-D-Ala carboxypeptidase, zinc D-Ala-D-Ala carboxypeptidase * : carboxypeptidase A2, carboxypeptidase A2 * : Membrane Pro-X carboxypeptidase, membrane Pro-Xaa carboxypeptidase * : tubulinyl-Tyr carboxypeptidase * : carboxypeptidase T * : Carboxypeptidase Taq * : Carboxypeptidase u, carboxypeptidase U * : Glutamate carboxypeptidase II * : metallocarboxypeptidase D * : angiotensin-converting enzyme 2 * : tubulin-glutamate carboxypeptidase * : *No Wikipedia article


EC 3.4.18 Cysteine type carboxypeptidases

* : cathepsin X


EC 3.4.19 Omega peptidases

* : acylaminoacyl-peptidase * : peptidyl-glycinamidase * : pyroglutamyl-peptidase I * EC 3.4.19.4: Deleted * : beta-aspartyl-peptidase, β-aspartyl-peptidase * : pyroglutamyl-peptidase II * : N-Formylmethionyl-peptidase, ''N''-formylmethionyl-peptidase * EC 3.4.19.8: now , glutamate carboxypeptidase II * : gamma-glutamyl hydrolase, folate γ-glutamyl hydrolase * EC 3.4.19.10: Now , ''N''-acetylmuramoyl-L-alanine amidase * : gamma-D-Glutamyl-meso-diaminopimelate peptidase, γ-Dglutamyl-''meso''-diaminopimelate peptidase * : ubiquitinyl hydrolase 1 * : glutathione hydrolase, glutathione γ-glutamate hydrolase * : leukotriene-C4 hydrolase, leukotriene-C4 hydrolase * : desampylase * * : glucosinolate γ-glutamyl hydrolase * : *No Wikipedia article


EC 3.4.21: Serine proteases

* : chymotrypsin * : chymotrypsin C * : metridin * : trypsin * : thrombin * : coagulation factor Xa * : plasmin * EC 3.4.21.8: Now (plasma kallikrein) and (tissue kallikrein) * : enteropeptidase * : acrosin * EC 3.4.21.11: Now , leukocyte elastase * : alpha-lytic endopeptidase, α-lytic endopeptidase * EC 3.4.21.13: Now , carboxypeptidase D * EC 3.4.21.14: now , endopeptidase So * EC 3.4.21.15: Now , oryzin * EC 3.4.21.16: Deleted * EC 3.4.21.17: Deleted * EC 3.4.21.18: Deleted * : glutamyl endopeptidase * : cathepsin G * : coagulation factor VIIa * : coagulation factor IXa * EC 3.4.21.23: Deleted * EC 3.4.21.24: Deleted * : cucumisin * : prolyl oligopeptidase * : coagulation factor XIa * EC 3.4.21.28: Now , venombin A * EC 3.4.21.29: Now , venombin A * EC 3.4.21.30: Now , venombin A * EC 3.4.21.31: Now , u-plasminogen activator * : brachyurin * EC 3.4.21.33: Deleted * : plasma kallikrein * : renal tissue kallikrein, tissue kallikrein * : pancreatic elastase * : leukocyte elastase * : coagulation factor XIIa * : chymase * EC 3.4.21.40: Deleted * : complement subcomponent C1r, Complement subcomponent C1r * : complement subcomponent C1s, complement subcomponent C1s * : classical-complement-pathway C3/C5 convertase * EC 3.4.21.44: Now , classical-complement-pathway C3/C5 convertase * : complement factor I * : complement factor D * : alternative-complement-pathway C3/C5 convertase * : cerevisin * : hypodermin C * : lysyl endopeptidase * EC 3.4.21.51: Deleted * EC 3.4.21.52: Deleted * : Endopeptidase La, edopeptidase La * : gamma-Renin, γ-renin * : venombin AB * EC 3.4.21.56: Now considered to be , cucumisin * : leucyl endopeptidase * EC 3.4.21.58: Deleted * : tryptase * : scutelarin * : kexin * : subtilisin * : oryzin * : endopeptidase K * : thermomycolin * : thermitase * : endopeptidase So * : t-Plasminogen activator, ''t''-plasminogen activator * : protein C (activated) * : pancreatic endopeptidase E * : pancreatic elastase II * : IgA-specific serine endopeptidase * : u-Plasminogen activator, u-plasminogen activator * : venombin A * : furin * : myeloblastin * : semenogelase * : granzyme A * : granzyme B * : streptogrisin A * : streptogrisin B * : glutamyl endopeptidase II * : oligopeptidase B * : limulus clotting factor C * : limulus clotting factor B * : limulus clotting enzyme * EC 3.4.21.87: Now , omptin * : repressor LexA * : signal peptidase I * : togavirin * : flavivirin * : endopeptidase Clp * : proprotein convertase 1 * : proprotein convertase 2 * : snake venom factor V activator * : lactocepin * : assemblin * : hepacivirin * : spermosin * : pseudomonalisin, sedolisin * : xanthomonalisin * : C-terminal processing peptidase, ''C''-terminal processing peptidase * : physarolisin * : mannan-binding lectin-associated serine protease-2 * : rhomboid protease * : hepsin * : peptidase Do * : HtrA2 peptidase * : matriptase * : C5a peptidase * : aqualysin 1 * : site-1 protease * : pestivirus NS3 polyprotein peptidase * : equine arterivirus serine peptidase * : infectious pancreatic necrosis birnavirus Vp4 peptidase * : SpoIVB peptidase * : stratum corneum chymotryptic enzyme * : kallikrein 8 * : kallikrein 13 * : oviductin * : Lys-Lys/Arg-Xaa endopeptidase * : *No Wikipedia article


EC 3.4.22 Cysteine proteases

* : cathepsin B * : papain * : ficain * EC 3.4.22.4: Now (stem bromelain) and (fruit bromelain) * EC 3.4.22.5: Now (stem bromelain) and (fruit bromelain) * : chymopapain * : asclepain * : clostripain * EC 3.4.22.9: Now , cerevisin * : streptopain * EC 3.4.22.11: Now , insulysin * EC 3.4.22.12: Now , γ-glutamyl hydrolase * EC 3.4.22.13: Deleted * : actinidain * : Cathepsin L2, cathepsin L * : cathepsin H * EC 3.4.22.17: Now , calpain-2 * EC 3.4.22.18: Now , prolyl oligopeptidase * EC 3.4.22.19: Now , thimet oligopeptidase * EC 3.4.22.20: Deleted * EC 3.4.22.21: Now , proteasome endopeptidase complex * EC 3.4.22.22: Now , saccharolysin * EC 3.4.22.23: Now , kexin * : Cathepsin T * : Glycyl endopeptidase * : Cancer procoagulant * : cathepsin S * : picornain 3C * : picornain 2A * : Caricain * : Ananain * : Stem bromelain * : Fruit bromelain * : Legumain * : Histolysain * : caspase-1 * : Gingipain R * : Cathepsin K * : adenain * : bleomycin hydrolase * : cathepsin F * : cathepsin O * : cathepsin V * : nuclear-inclusion-a endopeptidase * : helper-component proteinase * : L-peptidase, L-peptidase * : gingipain K * : staphopain * : separase * : V-cath endopeptidase * : cruzipain * : calpain-1 * : calpain-2 * : calpain-3 * : caspase-2 * : caspase-3 * : caspase-4 * : caspase-5 * : caspase-6 * : caspase-7 * : caspase-8 * : caspase-9 * : caspase-10 * : caspase-11 * : peptidase 1 (mite) * : calicivirin * : zingipain * : Ulp1 peptidase * : SARS coronavirus main proteinase * : sortase A * : sortase B


EC 3.4.23 Aspartic endopeptidases

* : pepsin A * : pepsin B * : gastricsin * : chymosin * : cathepsin D * EC 3.4.23.6: Now , pycnoporopepsin * EC 3.4.23.7: Now , penicillopepsin * EC 3.4.23.8: Now , saccharopepsin * EC 3.4.23.9: Now , rhizopuspepsin * EC 3.4.23.10: Now , endothiapepsin * EC 3.4.23.11: Deleted entry * : nepenthesin * EC 3.4.23.13: Deleted * EC 3.4.23.14: Deleted * : renin * : HIV-1 retropepsin * : Pro-opiomelanocortin converting enzyme, ''pro''-opiomelanocortin converting enzyme * : aspergillopepsin I * : aspergillopepsin II * : penicillopepsin * : rhizopuspepsin * : endothiapepsin * : mucorpepsin * : candidapepsin * : saccharopepsin * : rhodotorulapepsin * EC 3.4.23.27: Now , physarolisin * : acrocylindropepsin * : polyporopepsin * : pycnoporopepsin * : scytalidopepsin A * : scytalidopepsin B * EC 3.4.23.33: Now , xanthomonalisin * : cathepsin E * : barrierpepsin * : signal peptidase II * EC 3.4.23.37: Now , pseudomonalisin * : plasmepsin I * : plasmepsin II * : phytepsin * : yapsin 1 * : thermopsin * : prepilin peptidase * : nodavirus endopeptidase * : memapsin 1 * : memapsin 2 * : HIV-2 retropepsin * : plasminogen activator Pla * : omptin * : human endogenous retrovirus K endopeptidase * : HycI peptidase * : preflagellin peptidase


EC 3.4.24: Metallopeptidases

* : atrolysin A * : Deleted entry: Sepia proteinase * : microbial collagenase * : now serralysin * EC 3.4.24.5: Deleted entry: lens neutral proteinase. Now included with (calpain-2) and (proteasome endopeptidase complex) * : leucolysin * : interstitial collagenase * EC 3.4.24.8: Transferred entry: ''Achromobacter iophagus'' collagenase. Now , microbial collagenase * EC 3.4.24.9: Deleted entry: Trichophyton schoenleinii collagenase * EC 3.4.24.10: Deleted entry: Trichophyton mentagrophytes keratinase * : neprilysin * : envelysin * : IgA-specific metalloendopeptidase * : procollagen N-endopeptidase * : thimet oligopeptidase * : neurolysin * : stromelysin 1 * : meprin A * : procollagen C-endopeptidase * : peptidyl-Lys metalloendopeptidase * : astacin * : stromelysin 2 * : matrilysin * : gelatinase a * : vibriolysin * : pseudolysin * : thermolysin * : bacillolysin * : aureolysin * : coccolysin * : mycolysin * : beta-Lytic metalloendopeptidase, β-lytic metalloendopeptidase * : peptidyl-Asp metalloendopeptidase * : neutrophil collagenase * : gelatinase B * : leishmanolysin * : saccharolysin * : gametolysin * : deuterolysin * : serralysin * : atrolysin B * : atrolysin C * : atroxase * : atrolysin E * : atrolysin F * : adamalysin * : horrilysin * : ruberlysin * : bothropasin * : bothrolysin * : ophiolysin * : trimerelysin I * : trimerelysin II * : mucrolysin * : pitrilysin * : insulysin * : O-sialoglycoprotein endopeptidase, ''O''-sialoglycoprotein endopeptidase * : russellysin * : mitochondrial intermediate peptidase * : dactylysin * : nardilysin * : magnolysin * : meprin B * : mitochondrial processing peptidase * : macrophage elastase * : choriolysin L * : choriolysin H * : tentoxilysin * : bontoxilysin * : oligopeptidase A * : endothelin-converting enzyme 1 * : fibrolase * : jararhagin * : fragilysin * : lysostaphin * : flavastacin * : snapalysin * : gpr endopeptidase * : pappalysin-1 * : membrane-type matrix metalloproteinase-1 * : ADAM10 endopeptidase * : ADAMTS-4 endopeptidase * : anthrax lethal factor endopeptidase * : Ste24 endopeptidase * : S2P endopeptidase * : ADAM 17 endopeptidase * : ADAMTS13 endopeptidase


EC 3.4.25 Threonine endopeptidases

* : proteasome endopeptidase complex * : HslU—HslV peptidase * EC 3.4.99.7: Deleted entry: euphorbain * EC 3.4.99.8: Deleted entry: Gliocladium proteinase * EC 3.4.99.9: Deleted entry: hurain. Now considered to be , cucumisin * EC 3.4.99.10: Transferred entry: insulinase. Now , insulysin * EC 3.4.99.11: Deleted entry: Streptomyces alkalophilic keratinase * EC 3.4.99.12: Deleted entry: ''Trichophyton mentagrophytes'' keratinase * EC 3.4.99.13: Transferred entry: β-lytic proteinase (''Mycobacterium sorangium''). Now , β-lytic metalloendopeptidase * EC 3.4.99.14: Deleted entry: mexicanain * EC 3.4.99.15: Deleted entry: Paecilomyces proteinase * EC 3.4.99.16: Deleted entry: ''Penicillium notatum'' extracellular proteinase * EC 3.4.99.17: Deleted entry: peptidoglycan endopeptidase * EC 3.4.99.18: Deleted entry: pinguinain * EC 3.4.99.19: Transferred entry: renin. Now , renin * EC 3.4.99.20: Deleted entry: scopulariopsis proteinase * EC 3.4.99.21: Deleted entry: solanain. Now considered , cucumisin * EC 3.4.99.22: Transferred entry: staphylokinase. , aureolysin * EC 3.4.99.23: Deleted entry: tabernamontanain. Now considered EC 3.4.21.25, cucumisin * EC 3.4.99.24: Deleted entry: Tenebrio α-proteinase * EC 3.4.99.25: Transferred entry: trametes acid proteinase. , rhizopuspepsin * EC 3.4.99.26: Transferred entry: urokinase. Now , t-plasminogen activator * EC 3.4.99.27: Deleted entry: ''Echis carinatus'' prothrombin-activating proteinase * EC 3.4.99.28: Transferred entry: ''Oxyuranus scutellatus'' prothrombin-activating proteinase. , scutelarin * EC 3.4.99.29: Deleted entry: Myxobacter AL-1 proteinase I * EC 3.4.99.30: Transferred entry: Myxobacter AL-1 proteinase II. , peptidyl-Lys metalloendopeptidase * EC 3.4.99.31: Transferred entry: tissue endopeptidase degrading collagenase synthetic substrate. , thimet oligopeptidase * EC 3.4.99.32: Transferred entry: ''Armillaria mellea'' neutral proteinase. Now , peptidyl-Lys metalloendopeptidase * EC 3.4.99.33: Deleted entry: cathepsin R * EC 3.4.99.34: Deleted entry: mytilidase * EC 3.4.99.35: Transferred entry: premurein-leader peptidase. Now , signal peptidase II * EC 3.4.99.36: Transferred entry: leader peptidase. Now , signal peptidase I * EC 3.4.99.37: Deleted entry: RecA peptidase * EC 3.4.99.38: Transferred entry: pro-opiomelanotropin-converting proteinase. Now , pro-opiomelanocortin converting enzyme * EC 3.4.99.39: Deleted entry: pseudomurein endopeptidase * EC 3.4.99.40: Deleted entry: pro-gonadoliberin proteinase * EC 3.4.99.41: Transferred entry: mitochondrial processing peptidase. Now , mitochondrial processing peptidase * EC 3.4.99.42: Deleted entry: leucyllysine endopeptidase * EC 3.4.99.43: Transferred entry: thermopsin. Npw , thermopsin * EC 3.4.99.44: Transferred entry: pitrilysin. Now , pitrilysin * EC 3.4.99.45: Transferred entry: insulinase. Now , insulysin * EC 3.4.99.46: Transferred entry: multicatalytic endopeptidase complex. Now , proteasome endopeptidase complex


EC 3.5: Acting on carbon-nitrogen bonds, other than peptide bonds


3.5.1: In linear amides

* : asparaginase * : glutaminase * : omega-amidase, ω-amidase * : amidase * : urease * : beta-ureidopropionase, β-ureidopropionase * : ureidosuccinase * : formylaspartate deformylase * : arylformamidase * : formyltetrahydrofolate deformylase * : penicillin amidase * : biotinidase * : aryl-acylamidase * : aminoacylase, ''N''-acyl-aliphatic-L-amino acid amidohydrolase * : aspartoacylase * : acetylornithine deacetylase * : acyl-lysine deacylase * : succinyl-diaminopimelate desuccinylase * : nicotinamidase * : citrullinase * : N-acetyl-beta-alanine deacetylase, ''N''-acetyl-β-alanine deacetylas * : pantothenase * : ceramidase * : choloylglycine hydrolase * : N-acetylglucosamine-6-phosphate deacetylase, ''N''-acetylglucosamine-6-phosphate deacetylase * : N4-(beta-N-acetylglucosaminyl)-L-asparaginase, ''N''4-(β-''N''-acetylglucosaminyl)-L-asparaginase * EC 3.5.1.27: The activity is covered by , peptide deformylase * : N-acetylmuramoyl-L-alanine amidase, ''N''-acetylmuramoyl-L-alanine amidase * : 2-(acetamidomethylene)succinate hydrolase * : 5-aminopentanamidase * : formylmethionine deformylase * : hippurate hydrolase * : N-acetylglucosamine deacetylase, ''N''-acetylglucosamine deacetylase * EC 3.5.1.34: Identical with , Xaa-methyl-His dipeptidase * : D-glutaminase, D-glutaminase * : N-methyl-2-oxoglutaramate hydrolase, ''N''-methyl-2-oxoglutaramate hydrolase * EC 3.5.1.37: Delete, identical with ''N''4-(β-''N''-acetylglucosaminyl)-L-asparaginase * : glutamin-(asparagin-)ase * : alkylamidase * : acylagmatine amidase * : chitin deacetylase * : nicotinamide-nucleotide amidase * : peptidyl-glutaminase * : protein-glutamine glutaminase * EC 3.5.1.45: Now listed only as urea carboxylase * : 6-aminohexanoate-dimer hydrolase * : N-acetyldiaminopimelate deacetylase, ''N''-acetyldiaminopimelate deacetylase * : acetylspermidine deacetylase * : formamidase * : pentanamidase * : 4-acetamidobutyryl-CoA deacetylase * : peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase, peptide-''N''4-(''N''-acetyl-β-glucosaminyl)asparagine amidase * : N-carbamoylputrescine amidase, ''N''-carbamoylputrescine amidase * : allophanate hydrolase * : long-chain-fatty-acyl-glutamate deacylase * : N,N-dimethylformamidase, ''N,N''-dimethylformamidase * : tryptophanamidase * : N-benzyloxycarbonylglycine hydrolase, ''N''-benzyloxycarbonylglycine hydrolase * : N-carbamoylsarcosine amidase, ''N''-carbamoylsarcosine amidase * : N-(long-chain-acyl)ethanolamine deacylase, ''N''-(long-chain-acyl)ethanolamine deacylase * : mimosinase * : acetylputrescine deacetylase * : 4-acetamidobutyrate deacetylase * : Nalpha-benzyloxycarbonylleucine hydrolase, ''N''α-benzyloxycarbonylleucine hydrolase * : theanine hydrolase * : 2-(hydroxymethyl)-3-(acetamidomethylene)succinate hydrolase * : 4-methyleneglutaminase * : N-formylglutamate deformylase, ''N''-formylglutamate deformylase * : glycosphingolipid deacylase * : aculeacin-A deacylase * : N-feruloylglycine deacylase, ''N''-feruloylglycine deacylase * : D-benzoylarginine-4-nitroanilide amidase, D-benzoylarginine-4-nitroanilide amidase * : carnitinamidase * : chenodeoxycholoyltaurine hydrolase * : urethanase * : arylalkyl acylamidase * : N-carbamoyl-D-amino acid hydrolase, ''N''-carbamoyl-D-amino-acid hydrolase * : glutathionylspermidine amidase * : phthalyl amidase * EC 3.5.1.80: Identical to , ''N''-acetylglucosamine-6-phosphate deacetylase * : N-acyl-D-amino-acid deacylase, ''N''-acyl-D-amino-acid deacylase * : N-acyl-D-glutamate deacylase, ''N''-acyl-D-glutamate deacylase * : N-acyl-D-aspartate deacylase, ''N''-acyl-D-aspartate deacylase * : biuret amidohydrolase * : (S)-N-acetyl-1-phenylethylamine hydrolase, (''S'')-''N''-acetyl-1-phenylethylamine hydrolase * : mandelamide amidase * : N-carbamoyl-L-amino-acid hydrolase, ''N''-carbamoyl-L-amino-acid hydrolase * : peptide deformylase * : N-acetylglucosaminylphosphatidylinositol deacetylase, ''N''-acetylglucosaminylphosphatidylinositol deacetylase * : adenosylcobinamide hydrolase * : N-substituted formamide deformylase, ''N''-substituted formamide deformylase * : pantetheine hydrolase * : glutaryl-7-aminocephalosporanic-acid acylase * : gamma-glutamyl-gamma-aminobutyrate hydrolase, γ-glutamyl-γ-aminobutyrate hydrolase * : N-malonylurea hydrolase, ''N''-malonylurea hydrolase * : succinylglutamate desuccinylase * : acyl-homoserine-lactone acylase * : histone deacetylase * : fatty acid amide hydrolase * : (R)-amidase, (''R'')-amidase * : L-proline amide hydrolase, L-proline amide hydrolase * : 2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase, 2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3''H'')-one 5′-monophosphate deformylase * : N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase, ''N''-acetyl-1-D-myo-inositol-2-amino-2-deoxy-α-D-glucopyranoside deacetylase * : peptidoglycan-N-acetylglucosamine deacetylase, peptidoglycan-''N''-acetylglucosamine deacetylase * : chitin disaccharide deacetylase * : N-formylmaleamate deformylase, ''N''-formylmaleamate deformylase * : maleamate amidohydrolase * : UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-''O''-acyl-''N''-acetylglucosamine deacetylase * : sphingomyelin deacylase * : peroxyureidoacrylate/ureidoacrylate amidohydrolase, ureidoacrylate amidohydrolase * : 2-oxoglutaramate amidase * : 2'-N-acetylparomamine deacetylase, 2′-''N''-acetylparomamine deacetylase * : 2-acetyl-6-hydroxyneomycin C deacetylase, 2′′′-acetyl-6′′′-hydroxyneomycin C deacetylase * : ''N''-acyl-aromatic-L-amino acid amidohydrolase * * : mycothiol ''S''-conjugate amidase * * : ureidoglycolate amidohydrolase * * : 6-aminohexanoate-oligomer endohydrolase * * : γ-glutamyl hercynylcysteine ''S''-oxide hydrolase * * : Pup amidohydrolase * * EC 3.5.1.120: Now , 2-aminomuconate deaminase (2-hydroxymuconate-forming) * : protein ''N''-terminal asparagine amidohydrolase * * : protein ''N''-terminal glutamine amidohydrolase * * : γ-glutamylanilide hydrolase * * : protein deglycase * * : ''N'' 2-acetyl-L-2,4-diaminobutanoate deacetylase * * : oxamate amidohydrolase * * : jasmonoyl-L-amino acid hydrolase * * : deaminated glutathione amidase * * : ''N'' 5-(cytidine 5′-diphosphoramidyl)-L-glutamine hydrolase * * : [amino group carrier protein]-lysine hydrolase * * : 1-carboxybiuret hydrolase * * : [amino group carrier protein]-ornithine hydrolase * * : ''N'' α-acyl-L-glutamine aminoacylase * * : (indol-3-yl)acetyl-L-aspartate hydrolase * * : ''N'' 4-acetylcytidine amidohydrolase * * : ''N,N′''-diacetylchitobiose non-reducing end deacetylase * : *No Wikipedia article


3.5.2: In cyclic amides

* : barbiturase * : dihydropyrimidinase * : dihydroorotase * : carboxymethylhydantoinase * : allantoinase * : beta-lactamase, β-lactamase * : imidazolonepropionase * EC 3.5.2.8: Now included with , β-lactamase * : 5-oxoprolinase (ATP-hydrolysing) * : creatininase * : L-lysine-lactamase, L-lysine-lactamase * : 6-aminohexanoate-cyclic-dimer hydrolase * : 2,5-dioxopiperazine hydrolase * : N-methylhydantoinase (ATP-hydrolysing), ''N''-methylhydantoinase (ATP-hydrolysing) * : cyanuric acid amidohydrolase * : maleimide hydrolase * : hydroxyisourate hydrolase * : enamidase * : streptothricin hydrolase * : isatin hydrolase * : *No Wikipedia article


3.5.3: In linear amidines

* : arginase * : guanidinoacetase * : creatinase * : allantoicase * : formimidoylaspartate deiminase * : arginine deiminase * : guanidinobutyrase * : formimidoylglutamase * : allantoate deiminase * : D-arginase, D-arginase * : agmatinase * : agmatine deiminase * : formimidoylglutamate deiminase * : amidinoaspartase * : protein-arginine deiminase * : methylguanidinase * : guanidinopropionase * : dimethylargininase * EC 3.5.3.19: Now , ureidoglycolate amidohydrolase * : diguanidinobutanase * : Methylenediurea deaminase * : proclavaminate amidinohydrolase * : N-succinylarginine dihydrolase, ''N''-succinylarginine dihydrolase * : ''N'' 1-aminopropylagmatine ureohydrolase * * : ''N'' ω-hydroxy-L-arginine amidinohydrolase * * : (''S'')-ureidoglycine aminohydrolase * : *No Wikipedia article


3.5.4: In cyclic amidines

* : cytosine deaminase * : adenine deaminase * : guanine deaminase * : adenosine deaminase * : cytidine deaminase * : AMP deaminase * : ADP deaminase * : aminoimidazolase * : methenyltetrahydrofolate cyclohydrolase * : IMP cyclohydrolase * : pterin deaminase * : dCMP deaminase * : dCTP deaminase * EC 3.5.4.14: Now included in , (deoxy)cytidine deaminase * : guanosine deaminase * : GTP cyclohydrolase I * : adenosine-phosphate deaminase * : ATP deaminase * : phosphoribosyl-AMP cyclohydrolase * : pyrithiamine deaminase * : creatinine deaminase * : 1-pyrroline-4-hydroxy-2-carboxylate deaminase * : blasticidin-S deaminase * : sepiapterin deaminase * : GTP cyclohydrolase II * : diaminohydroxyphosphoribosylaminopyrimidine deaminase * : methenyltetrahydromethanopterin cyclohydrolase * : S-adenosylhomocysteine deaminase, ''S''-adenosylhomocysteine deaminase * : GTP cyclohydrolase IIa * : dCTP deaminase (dUMP-forming) * : S-methyl-5'-thioadenosine deaminase, ''S''-methyl-5′-thioadenosine deaminase * : 8-oxoguanine deaminase * : tRNA(adenine34) deaminase * * : tRNAAla(adenine37) deaminase * * : tRNA(cytosine8) deaminase * * : mRNA(cytosine6666) deaminase * * : double-stranded RNA adenine deaminase * * : single-stranded DNA cytosine deaminase * * : GTP cyclohydrolase IV * * : aminodeoxyfutalosine deaminase * * : 5'-deoxyadenosine deaminase * : ''N''-isopropylammelide isopropylaminohydrolase * * : hydroxydechloroatrazine ethylaminohydrolase * * : ectoine hydrolase * * : melamine deaminase * * : cAMP deaminase * : *No Wikipedia article


3.5.5: In nitriles

* : nitrilase * : ricinine nitrilase * EC 3.5.5.3: Now , cyanate hydratase * : cyanoalanine nitrilase * : arylacetonitrilase * : bromoxynil nitrilase * : aliphatic nitrilase * : thiocyanate hydrolase


3.5.99: In other compounds

* : riboflavinase * : aminopyrimidine aminohydrolase * EC 3.5.99.3: Now , hydroxydechloroatrazine ethylaminohydrolase * EC 3.5.99.4: Now , ''N''-isopropylammelide isopropylaminohydrolase * : 2-aminomuconate deaminase * : glucosamine-6-phosphate deaminase * : 1-aminocyclopropane-1-carboxylate deaminase * : 5-nitroanthranilic acid aminohydrolase * : 2-nitroimidazole nitrohydrolase * : 2-iminobutanoate/2-iminopropanoate deaminase * * : 2-aminomuconate deaminase (2-hydroxymuconate-forming) * : *No Wikipedia article


EC 3.6: Acid anhydride hydrolases, Acting on acid anhydrides


3.6.1: In phosphorus-containing anhydrides

* : inorganic diphosphatase * : trimetaphosphatase * : adenosinetriphosphatase * EC 3.6.1.4: Now included with , adenosinetriphosphatase * : apyrase * : nucleoside-diphosphatase, nucleoside diphosphate phosphatase * : acylphosphatase * : ATP diphosphatase * : nucleotide diphosphatase * : endopolyphosphatase * : exopolyphosphatase * : dCTP diphosphatase * : ADP-ribose diphosphatase * : adenosine-tetraphosphatase * : nucleoside-triphosphatase * : CDP-glycerol diphosphatase * : bis(5'-nucleosyl)-tetraphosphatase (asymmetrical), bis(5′-nucleosyl)-tetraphosphatase (asymmetrical)) * : FAD diphosphatase * EC 3.6.1.19: Now , nucleotide diphosphatase * : 5'-acylphosphoadenosine hydrolase, 5′-acylphosphoadenosine hydrolase * : ADP-sugar diphosphatase * : NAD+ diphosphatase, NAD+ diphosphatase * : dUTP diphosphatase * : nucleoside phosphoacylhydrolase * : triphosphatase * : CDP-diacylglycerol diphosphatase * : undecaprenyl-diphosphatase * : thiamine-triphosphatase * : bis(5'-adenosyl)-triphosphatase, bis(5′-adenosyl)-triphosphatase * EC 3.6.1.30: Now covered by [m7GpppX diphosphatase] and [m7GpppN-mRNA hydrolase]. * : phosphoribosyl-ATP diphosphatase * EC 3.6.1.32: Now , myosin ATPase * EC 3.6.1.33: Now , dynein ATPase * EC 3.6.1.34: Transferred entry: H+-transporting ATP synthase. Now , H+-transporting two-sector ATPase * EC 3.6.1.35: Now , H+-exporting ATPase * EC 3.6.1.36: Now , H+/K+-exchanging ATPase * EC 3.6.1.37: Now , Na+/K+-exchanging ATPase * EC 3.6.1.38: Now , Ca2+-transporting ATPase * : thymidine-triphosphatase * : guanosine-5'-triphosphate,3'-diphosphate diphosphatase, guanosine-5′-triphosphate,3′-diphosphate phosphatase * : bis(5'-nucleosyl)-tetraphosphatase (symmetrical), bis(5′-nucleosyl)-tetraphosphatase (symmetrical) * : guanosine-diphosphatase * : dolichyldiphosphatase * : oligosaccharide-diphosphodolichol diphosphatase * : UDP-sugar diphosphatase * EC 3.6.1.46: Now , heterotrimeric G-protein GTPase * EC 3.6.1.47: Now , protein-synthesizing GTPase * EC 3.6.1.49: Now , signal-recognition-particle GTPase * EC 3.6.1.50: Now , dynamin GTPase * EC 3.6.1.51: Now , tubulin GTPase * : diphosphoinositol-polyphosphate diphosphatase * : Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase, Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase * : UDP-2,3-diacylglucosamine diphosphatase * : 8-oxo-dGTP diphosphatase * : 2-hydroxy-dATP diphosphatase * : UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase, UDP-2,4-diacetamido-2,4,6-trideoxy-β-L-altropyranose hydrolase * : 8-oxo-dGDP phosphatase * : m7GpppX diphosphatase, 5′-(N7-methyl 5′-triphosphoguanosine)-[mRNA] diphosphatase * : diadenosine hexaphosphate hydrolase (AMP-forming) * : diadenosine hexaphosphate hydrolase (ATP-forming) * : m7GpppN-mRNA hydrolase, 5′-(N7-methylguanosine 5′-triphospho)-[mRNA] hydrolase * : alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase, α-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase * : inosine diphosphate phosphatase * * : (d)CTP diphosphatase * * : XTP/dITP diphosphatase * * : dihydroneopterin triphosphate diphosphatase * * : geranyl diphosphate phosphohydrolase * * : 8-oxo-(d)GTP phosphatase * * : guanosine-5′-diphospho-5′- NAdiphosphatase * * : adenosine-5′-diphospho-5′- NAdiphosphatase * * : DNA-3′-diphospho-5′-guanosine diphosphatase * * : inosine/xanthosine triphosphatase * * : mRNA 5′-phosphatase * : *No Wikipedia article


3.6.2: In sulfonyl-containing anhydrides

* : adenylylsulfatase * : phosphoadenylylsulfatase


3.6.3: Acting on acid anhydrides to catalyse transmembrane movement of substances

* : phospholipid-translocating ATPase * EC 3.6.3.2: Now , P-type Mg2+ transporter * EC 3.6.3.3: Now , Cd2+-exporting ATPase * EC 3.6.3.4: Now , Cu2+-exporting ATPase * EC 3.6.3.5: Now , Zn2+-exporting ATPase * EC 3.6.3.6: Now , P-type H+-exporting transporter * EC 3.6.3.7: Now , P-type Na+ transporter * EC 3.6.3.8: Now , Ca2+-transporting ATPase * EC 3.6.3.9: Now , Na+/K+-exchanging ATPase * EC 3.6.3.10: Now , H+/K+-exchanging ATPase * EC 3.6.3.11: Cl–-transporting ATPase. The activity was only ever studied in crude extracts, and is an artifact * EC 3.6.3.12: Now , K+-transporting ATPase * EC 3.6.3.13:Identical to , phospholipid-translocating ATPase * EC 3.6.3.14: Now , H+-transporting two-sector ATPase * EC 3.6.3.15: Now , Na+-transporting two-sector ATPase * EC 3.6.3.16: Now , arsenite-transporting ATPase * EC 3.6.3.17: Now covered by various ABC-type monosaccharide transporters in sub-subclass EC 7.5.2 * EC 3.6.3.18: Now , ABC-type oligosaccharide transporter * EC 3.6.3.19: Now , ABC-type maltose transporter * EC 3.6.3.20: Now , glycerol-3-phosphate-transporting ATPase * EC 3.6.3.21: Now , ABC-type polar-amino-acid transporter * EC 3.6.3.22: Now , ABC-type nonpolar-amino-acid transporter * EC 3.6.3.23: Now , oligopeptide-transporting ATPase * EC 3.6.3.24: Now , nickel-transporting ATPase * EC 3.6.3.25: Now , sulfate-transporting ATPase * EC 3.6.3.26: Now , nitrate-transporting ATPase * EC 3.6.3.27: Now , ABC-type phosphate transporter * EC 3.6.3.28: Now , ABC-type phosphonate transporter * EC 3.6.3.29: Now , molybdate-transporting ATPase * EC 3.6.3.30: Now , Fe3+-transporting ATPase * EC 3.6.3.31: Now , polyamine-transporting ATPase * EC 3.6.3.32: Now , quaternary-amine-transporting ATPase * EC 3.6.3.33: Now , vitamin B12-transporting ATPase * EC 3.6.3.34: now recognized to be at least three separate enzymes , iron(III) hydroxamate ABC transporter, , ferric enterobactin ABC transporter, and , ferric citrate ABC transporter * EC 3.6.3.35: Now , manganese-transporting ATPase * EC 3.6.3.36: Now , taurine-transporting ATPase * EC 3.6.3.37: Now , guanine-transporting ATPase * EC 3.6.3.38: Now , ABC-type capsular-polysaccharide transporter * EC 3.6.3.39: Now , lipopolysaccharide-transporting ATPase * EC 3.6.3.40: Now , teichoic-acid-transporting ATPase * EC 3.6.3.41: Now , heme-transporting ATPase * EC 3.6.3.42: Now , β-glucan-transporting ATPase * EC 3.6.3.43: Now , peptide-transporting ATPase * EC 3.6.3.44: Now , ABC-type xenobiotic transporter * EC 3.6.3.45: Now included with , xenobiotic-transporting ATPase * EC 3.6.3.46: Now , ABC-type Cd2+ transporter * EC 3.6.3.47: Now , fatty-acyl-CoA-transporting ATPase * EC 3.6.3.48: Now as α-factor-pheromone transporting ATPase * EC 3.6.3.49: Now , channel-conductance-controlling ATPase * EC 3.6.3.50: Now , protein-secreting ATPase * EC 3.6.3.51: Now , mitochondrial protein-transporting ATPase * EC 3.6.3.52: Now , chloroplast protein-transporting ATPase * EC 3.6.3.53: Now , Ag+-exporting ATPase * EC 3.6.3.54: Now , Cu+-exporting ATPase * EC 3.6.3.55: Now , tungstate-importing ATPase


3.6.4: Acting on acid anhydrides to facilitate cellular and subcellular movement

* EC 3.6.4.1: Now , myosin ATPase * EC 3.6.4.2: Now , dynein ATPase * EC 3.6.4.3: Now , microtubule-severing ATPase * EC 3.6.4.4: Now , plus-end-directed kinesin ATPase * EC 3.6.4.5: Now , minus-end-directed kinesin ATPase * : vesicle-fusing ATPase * : peroxisome-assembly ATPase * EC 3.6.4.8: Now , proteasome ATPase * EC 3.6.4.9: Now , chaperonin ATPase * : non-chaperonin molecular chaperone ATPase * EC 3.6.4.11: Deleted, the activity has been shown not to take place * : DNA helicase * : RNA helicase


3.6.5: Acting on GTP to facilitate cellular and subcellular movement

* : heterotrimeric G-protein GTPase * : small monomeric GTPase * : protein-synthesizing GTPase * : signal-recognition-particle GTPase * : dynamin GTPase * : tubulin GTPase


EC 3.7: Acting on carbon-carbon bonds


EC 3.7.1: In ketonic substances

* : oxaloacetase * : fumarylacetoacetase * : kynureninase * : phloretin hydrolase * : acylpyruvate hydrolase * : acetylpyruvate hydrolase * : beta-diketone hydrolase, β-diketone hydrolase * : 2,6-dioxo-6-phenylhexa-3-enoate hydrolase * : 2-hydroxymuconate-semialdehyde hydrolase * : cyclohexane-1,3-dione hydrolase * : cyclohexane-1,2-dione hydrolase * : cobalt-precorrin 5A hydrolase * : 2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoate hydrolase * : 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase * EC 3.7.1.15: Now , (+)-caryolan-1-ol synthase * EC 3.7.1.16: Now , oxepin-CoA hydrolase * : 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase * : 6-oxocamphor hydrolase * : 2,6-dihydroxypseudooxynicotine hydrolase * : 3-fumarylpyruvate hydrolase * : 6-oxocyclohex-1-ene-1-carbonyl-CoA hydratase * * : 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (ring-opening) * : maleylpyruvate hydrolase * * : 2,4-diacetylphloroglucinol hydrolase * * : 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase * * : 2,4-didehydro-3-deoxy-L-rhamnonate hydrolase * * : neryl diphosphate diphosphatase * * : 3-oxoisoapionate-4-phosphate transcarboxylase/hydrolase * : *No Wikipedia article


EC 3.8: Acting on halide bonds


EC 3.8.1: Acting on halide bonds

* EC 3.8.1.1: Covered by , haloalkane dehalogenase. * : 2-haloacid dehalogenase, (''S'')-2-haloacid dehalogenase * : haloacetate dehalogenase * EC 3.8.1.4: Now , thyroxine 5′-deiodinase * : haloalkane dehalogenase * : 4-chlorobenzoate dehalogenase * : 4-chlorobenzoyl-CoA dehalogenase * : atrazine chlorohydrolase * : (R)-2-haloacid dehalogenase, (''R'')-2-haloacid dehalogenase * : 2-haloacid dehalogenase (configuration-inverting) * : 2-haloacid dehalogenase (configuration-retaining)


3.8.2: In phosphorus-halide compounds (deleted sub-subclass)

* EC 3.8.2.1: Now , diisopropyl-fluorophosphatase


EC 3.9: act on phosphorus-nitrogen bonds


EC 3.9.1: Acting on phosphorus-nitrogen bonds (only sub-subclass identified to date)

* : phosphoamidase * : protein arginine phosphatase * * : phosphohistidine phosphatase * : *No Wikipedia article


EC 3.10: Acting on sulfur-nitrogen bonds


EC 3.10.1: Acting on sulfur-nitrogen bonds (only sub-subclass identified to date)

* : N-sulfoglucosamine sulfohydrolase, ''N''-sulfoglucosamine sulfohydrolase * : cyclamate sulfohydrolase


EC 3.11: Acting on carbon-phosphorus bonds


EC 3.11.1: Acting on carbon-phosphorus bonds (only sub-subclass identified to date)

* : phosphonoacetaldehyde hydrolase * : phosphonoacetate hydrolase * : phosphonopyruvate hydrolase


EC 3.12: Acting on sulfur-sulfur bonds


EC 3.12.1: Acting on sulfur-sulfur bonds (only sub-subclass identified to date)

* : trithionate hydrolase


EC 3.13: Acting on carbon-sulfur bonds


EC 3.13.1: Acting on carbon-sulfur bonds (only sub-subclass identified to date)

* : UDP-sulfoquinovose synthase * EC 3.13.1.2: Deleted, the activity is most probably attributable to , ''S''-ribosylhomocysteine lyase * : 2'-hydroxybiphenyl-2-sulfinate desulfinase, 2′-hydroxybiphenyl-2-sulfinate desulfinase * : 3-sulfinopropanoyl-CoA desulfinase * * : carbon disulfide hydrolase * : [CysO sulfur-carrier protein]-''S''-L-cysteine hydrolase * * : Carbonyl sulfide hydrolase * : ''S''-adenosyl-L-methionine hydrolase (adenosine-forming * * : ''S''-inosyl-L-homocysteine hydrolase * : *No Wikipedia article


References

{{Reflist Hydrolases, * Biology-related lists, EC3