Purified duck embryo vaccine (PDEV) was the first
vaccine
A vaccine is a biological preparation that provides active acquired immunity to a particular infectious or malignant disease. The safety and effectiveness of vaccines has been widely studied and verified.[ ...]
developed for human use in treating pre- and postexposure to the
rabies virus
Rabies virus, scientific name ''Rabies lyssavirus'', is a neurotropic virus that causes rabies in humans and animals. Rabies transmission can occur through the saliva of animals and less commonly through contact with human saliva. ''Rabies lys ...
. It was developed in 1957 and was made of dried, killed rabies virus. Vaccination with PDEV involved a series of intradermal injections over several days. The
World Health Organization
The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health. The WHO Constitution states its main objective as "the attainment by all peoples of the highest possible level o ...
still includes PDEV in its list of recommended vaccines for treatment of rabies virus exposure. However, newer vaccines are more commonly used. These include the
human diploid cell vaccine (HDCV) first introduced in 1978; purified chicken embryo cell vaccine (PCECV), developed in 1984; and a purified Vero cell rabies vaccine (PVCRV) developed in 1986.
[Centers for Disease Control Morbidity and Mortality Weekly Report. Atlanta. January 08, 1999 /48(RR-1);1-21]
See also
*
List of vaccine ingredients
*
List of vaccine topics
This is a list of vaccine-related topics.
A vaccine is a biological preparation that improves immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing microorganism, and is often made from weakene ...
*
Reverse vaccinology
Reverse vaccinology is an improvement of vaccinology that employs bioinformatics and reverse pharmacology practices, pioneered by Rino Rappuoli and first used against Serogroup B meningococcus. Since then, it has been used on several other ba ...
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Virosome
A virosome is a drug or vaccine delivery mechanism consisting of unilamellar phospholipid membrane (either a mono- or bi-layer) vesicle incorporating virus derived proteins to allow the virosomes to fuse with target cells. Viruses are infectious ...
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Immunity
Immunity may refer to:
Medicine
* Immunity (medical), resistance of an organism to infection or disease
* ''Immunity'' (journal), a scientific journal published by Cell Press
Biology
* Immune system
Engineering
* Radiofrequence immunity desc ...
References
External links
*
WHO Vaccine preventable diseases and immunizationThe History of Vaccines from the
College of Physicians of Philadelphia
The College of Physicians of Philadelphia is the oldest private medical society in the United States. Founded in 1787 by 24 Philadelphia physicians "to advance the Science of Medicine, and thereby lessen human misery, by investigating the disease ...
University of Oxford Vaccinology Programme: a series of short courses in vaccinology
Vaccination
Virology
Rabies
{{Vaccines , state=expanded