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The Drug Effectiveness Review Project (DERP) is a trailblazing, self-governed collaboration of state
Medicaid Medicaid in the United States is a federal and state program that helps with healthcare Health care or healthcare is the improvement of health via the prevention, diagnosis, treatment, amelioration or cure of disease, illness, injury, and ...
and public pharmacy programs that commission high-quality evidence-based research products to assist policymakers and other decision-makers grappling with difficult drug coverage decisions. Housed at the Center for Evidence-based Policy at
Oregon Health & Science University Oregon Health & Science University (OHSU) is a public research university focusing primarily on health sciences with a main campus, including two hospitals, in Portland, Oregon. The institution was founded in 1887 as the University of Oregon Med ...
in Portland,
Oregon Oregon () is a state in the Pacific Northwest region of the Western United States. The Columbia River delineates much of Oregon's northern boundary with Washington, while the Snake River delineates much of its eastern boundary with Idah ...
, DERP produces concise, comparative, evidence-based research products that evaluate the efficacy, effectiveness, and safety of
drugs A drug is any chemical substance that causes a change in an organism's physiology or psychology when consumed. Drugs are typically distinguished from food and substances that provide nutritional support. Consumption of drugs can be via inhalat ...
in many widely used drug classes. Nationally recognized for its clinical objectivity and high-quality research, DERP focuses on specialty and other high-impact drugs – particularly those that have potential to change clinical practice. The program's goal is to ultimately help improve appropriate patient access, safety, and quality of care while helping government programs contain exploding costs for new pharmaceutical therapies. DERP uses a collaborative governing model to develop work plans that provide independent and objective research on drug effectiveness and safety to bring evidence to health policy decisions. DERP reports include up-to-date clinical evidence on efficacy, adverse events, and safety information for the drugs reviewed. These reports and research products are not usage guidelines, nor should they be read as an endorsement of or recommendation for any particular drug, use or approach. Rather, DERP reports are used by policy makers to develop criteria for drug coverage, such as prior authorizations, clinical edits, drug utilization management policies, and provider or patient education materials. DERP research products include a comprehensive search of the global evidence, an objective appraisal of the quality of the studies found, and a thorough synthesis of high-quality evidence. Policymakers are able to use these reports and research products to make informed policy decisions that improve patient outcomes and contain costs.


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External links


The Drug Effectiveness Review Project
Pharmacological societies Systematic review {{drug-stub