Doramectin, sold under the brand name Dectomax among others, is a
veterinary medication approved by the US
Food and Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is respo ...
(FDA) for the treatment of parasites such as gastrointestinal
roundworms,
lungworms,
eyeworms,
grubs,
sucking lice, and
mange mites in cattle.
It is available as a
generic medication
A generic drug is a pharmaceutical drug that contains the same chemical substance as a drug that was originally protected by chemical patents. Generic drugs are allowed for sale after the patents on the original drugs expire. Because the active ch ...
.
It is available as a combination with
levamisole
Levamisole, sold under the brand name Ergamisol among others, is a medication used to treat parasitic worm infections, specifically ascariasis and hookworm infections. It is taken by mouth.
Side effects may include abdominal pain, vomiting, ...
under the brand name Valcor.
It is used for the treatment and control of internal parasitosis (gastrointestinal and pulmonary nematodes), ticks and mange (and other ectoparasites). Doramectin is a derivative of
avermectin. Similarly to other drugs of this family, it is produced by fermentation by selected strains of ''
Streptomyces avermitilis'' followed by chemical modification.
Its spectrum includes: ''
Haemonchus,
Ostertagia,
Trichostrongylus,
Cooperia'', and ''
Oesophagostomum'' species and ''
Dictyocaulus viviparus'', ''
Dermatobia hominis,
Boophilus microplus'', and ''
Psoroptes bovis'', among many other internal and external parasites. It is available as an
injection and as a
topical
A topical medication is a medication that is applied to a particular place on or in the body. Most often topical medication means application to body surfaces such as the skin or mucous membranes to treat ailments via a large range of classes ...
solution.
Society and culture
Legal status
In November 2024, the FDA approved doramectin (brand name Doracide) for the treatment and control of gastrointestinal roundworms, lungworms, eyeworms, grubs, biting and sucking lice, horn flies, and mange mites in cattle.
[ ]fda.gov
/ref>
Brand names
Doramectin is marketed under the brand name Doramec L.A. for cattle, sheep, and swine.
Doramectin is available for horses as an oral, flavored, bioadhesive gel under the name Doraquest L.A. Oral Gel. It can be used to control and treat internal parasites as roundworms, lungworms and some external parasites.
References
{{Endectocides
Anthelmintics
Veterinary drugs