Chlormerodrin is a
mercurial diuretic
Mercurial diuretics are a form of renal diuretic containing mercury.
Although previously widely used, they have largely been superseded by safer diuretics such as thiazides, and are now rarely used. History and mechanism
Inorganic mercury compou ...
commercially traded from 1952 until 1974 that was once used to treat patients with
heart failure
Heart failure (HF), also known as congestive heart failure (CHF), is a syndrome caused by an impairment in the heart's ability to Cardiac cycle, fill with and pump blood.
Although symptoms vary based on which side of the heart is affected, HF ...
,
but is no longer in widespread use. The radiolabelled form (
197Hg &
203Hg) had also been used for medical imaging of the kidney and brain
and the
197Hg form was even considered a contender for
99mTc by some physicians,
but was ultimately discontinued by the FDA in 1989.
[FDA, Approved Drug Products with Therapeutic Equivalence Evaluations, US Department Of Health And Human Service, 1989.]
References
Mercurial diuretics
Ureas
Withdrawn drugs
X
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