Distefano is a surname. Notable people with the surname include:
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Benny Distefano (born 1962), American baseball player
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Chris Distefano (born 1984), American comedian
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David Distéfano (born 1987), Argentine footballer
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Tony DiStefano
Anthony Joseph DiStefano Jr. (born February 6, 1957) is an American former professional motocross racer. He competed in the AMA Motocross Championships from 1973 to 1981. A three-time AMA 250cc motocross national champion, DiStefano was inducted ...
(born 1957), American motocross racer
{{Stephen-surname
Spanish-language surnames
Italian-language surnames
Surnames from given names