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Difemetorex ( INN; sold as Cleofil), also known as diphemethoxidine, is a
stimulant Stimulants (also often referred to as psychostimulants or colloquially as uppers) is an overarching term that covers many drugs including those that increase activity of the central nervous system and the body, drugs that are pleasurable and inv ...
drug A drug is any chemical substance that causes a change in an organism's physiology or psychology when consumed. Drugs are typically distinguished from food and substances that provide nutritional support. Consumption of drugs can be via insuffla ...
of the piperidine class which was used as an appetite suppressant, but produced intolerable side effects such as insomnia which limited its clinical use. It was introduced in France by Ciba-Geigy in 1966 but is now no longer marketed.


Synthesis

Alkylation of desoxypipradrol with ethyleneoxide gives difemetorex.


See also

*
Desoxypipradrol Desoxypipradrol, also known as 2-⁠diphenylmethylpiperidine (2-DPMP), is a drug developed by Ciba in the 1950s which acts as a norepinephrine-dopamine reuptake inhibitor (NDRI). Chemistry Desoxypipradrol is closely related on a structural lev ...
* Diphenylprolinol *
SCH-5472 SCH-5472. is a stimulant drug developed by Schering-Plough in the 1950s. Synthesis Potassium amide was made from the reaction of potassium metal with liquid ammonia. The coupling between the carbanion created from diphenylmethane 01-81-5(1) a ...


References

{{Monoamine reuptake inhibitors Primary alcohols Anorectics Norepinephrine–dopamine reuptake inhibitors 2-Benzylpiperidines Stimulants Abandoned drugs