Dicyclohexyl Phosphorofluoridate
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Dicyclohexyl phosphorofluoridate (DCFP), also known as TL-941 or T-1840, is an extremely toxic
organophosphorus compound Organophosphorus chemistry is the scientific study of the synthesis and properties of organophosphorus compounds, which are organic compounds containing phosphorus. They are used primarily in pest control as an alternative to chlorinated hydrocarbo ...
with powerful
anticholinesterase Cholinesterase inhibitors (ChEIs), also known as anti-cholinesterase, are chemicals that prevent the breakdown of the neurotransmitter acetylcholine or butyrylcholine by cholinesterase. This increases the amount of the acetylcholine or butyryl ...
action. It's a colorless liquid that is extremely resistant to
hydrolysis Hydrolysis (; ) is any chemical reaction in which a molecule of water breaks one or more chemical bonds. The term is used broadly for substitution reaction, substitution, elimination reaction, elimination, and solvation reactions in which water ...
. DCFP can be produced by reaction of
cyclohexanol Cyclohexanol is the organic compound with the formula HOCH(CH2)5. The molecule is related to cyclohexane by replacement of one hydrogen atom by a hydroxyl group. This compound exists as a deliquescent colorless solid with a camphor-like odor, whi ...
with
phosphoryl dichloride fluoride Phosphoryl dichloride flouride is an inorganic compound with the chemical formula . Synthesis It is made by reacting phosphorus pentachloride with potassium monofluorophosphate: : Reactions The reaction with two equivalents of cyclohexanol yi ...
.


See also

* Diisopropyl phosphorofluoridate (DFP)


References

{{Acetylcholine metabolism and transport modulators Acetylcholinesterase inhibitors Phosphorofluoridates Cyclohexyl compounds