enzymology An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different mol ...

, a diacylglycerol cholinephosphotransferase () is an

enzyme An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different mol ...

that catalyzes the

chemical reaction A chemical reaction is a process that leads to the chemistry, chemical transformation of one set of chemical substances to another. When chemical reactions occur, the atoms are rearranged and the reaction is accompanied by an Gibbs free energy, ...

Diacylglycerol cholinephosphotransferase

CDP-choline + 1,2-diacylglycerol

\rightleftharpoons

CMP + a phosphatidylcholine

Thus, the two substrates of this enzyme are CDP-choline and 1,2-diacylglycerol, whereas its two products are CMP and phosphatidylcholine.

Classification

This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups.

Nomenclature

The

systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivi ...

of this enzyme class is CDP choline:1,2-diacylglycerol cholinephosphotransferase. Other names in common use include: * 1-alkyl-2-acetyl-m-glycerol:CDPcholine choline phosphotransferase, * 1-alkyl-2-acetyl-sn-glycerol cholinephosphotransferase, * 1-alkyl-2-acetylglycerol cholinephosphotransferase, * alkylacylglycerol choline phosphotransferase, * alkylacylglycerol cholinephosphotransferase, * CDP-choline diglyceride phosphotransferase, * cholinephosphotransferase, * CPT, * cytidine diphosphocholine glyceride transferase, * cytidine diphosphorylcholine diglyceride transferase, * diacylglycerol choline phosphotransferase, * phosphocholine diacylglyceroltransferase, * phosphorylcholine-glyceride transferase, and * sn-1,2-diacylglycerol cholinephosphotransferase.

Biological role

This enzyme participates in 3 metabolic pathways: aminophosphonate metabolism, glycerophospholipid metabolism, and ether lipid metabolism.

References

* * * EC 2.7.8 Enzymes of unknown structure {{2.7-enzyme-stub