Dextranomer (trade name Debrisan, Exudex) is a

cicatrizant D03A Cicatrizants D03AA Cod-liver oil ointments D03AX Other cicatrizants :D03AX01 Cadexomer iodine :D03AX02 Dextranomer :D03AX03 Dexpanthenol :D03AX04 Calcium pantothenate :D03AX05 Hyaluronic acid :D03AX06 Becaplermin :D03AX09 Crilanomer ...

used in dressings for wound healing, and in pharmaceutical products to treat

fecal incontinence Fecal incontinence (FI), or in some forms encopresis, is a lack of control over defecation, leading to involuntary loss of bowel contents, both liquid stool elements and mucus, or solid feces. When this loss includes flatus (gas), it is referre ...

. It consists of

dextran Dextran is a complex branched glucan (polysaccharide derived from the condensation of glucose), originally derived from wine. IUPAC defines dextrans as "Branched poly-α-d-glucosides of microbial origin having glycosidic bonds predominantly C-1 � ...

polymer chains cross-linked into a three-dimensional network.Solesta Package Insert
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Solesta

Solesta is the marketed brand name of a system of injections of dextranomer in stabilized

sodium hyaluronate Sodium hyaluronate is the sodium salt of hyaluronic acid, a glycosaminoglycan found in various connective tissue of humans. Chemistry Sodium hyaluronate is the sodium salt of hyaluronic acid. It is a glycosaminoglycan and long-chain polymer of d ...

for use in fecal incontinence (FI). This preparation is a biocompatible gel, for use as a perianal injectable bulking agent. The system is intended to be injected in the submucosal layer of the proximal

anal canal The anal canal is the part that connects the rectum to the anus, located below the level of the pelvic diaphragm. It is located within the anal triangle of the perineum, between the right and left ischioanal fossa. As the final functional segm ...

(i.e. above the level of the

dentate line The pectinate line (dentate line) is a line which divides the upper two-thirds and lower third of the anal canal. Developmentally, this line represents the hindgut The hindgut (or epigaster) is the posterior (caudal) part of the alimentary c ...

References

External links

* Dermatologic drugs Organic polymers {{dermatologic-drug-stub