Derrubone is a

prenylated Prenylation (also known as isoprenylation or lipidation) is the addition of hydrophobic molecules to a protein or a biomolecule. It is usually assumed that prenyl groups (3-methylbut-2-en-1-yl) facilitate attachment to cell membranes, similar to ...

isoflavone Isoflavones are substituted derivatives of isoflavone, a type of naturally occurring isoflavonoids, many of which act as phytoestrogens in mammals. Isoflavones are produced almost exclusively by the members of the bean family, Fabaceae (Leguminosae ...

, a type of flavonoid. It was originally isolated from the Indian tree ''

Derris robusta ''Derris robusta'' is a tree species in the genus ''Derris'' found in India. Derrubone is an isoflavone, a type of flavonoid, originally isolated from ''D. robusta''. References External links Millettieae Plants described in 1 ...

''. Recent research indicates that it acts as an inhibitor of Hsp90 to its function as a

chaperone protein In molecular biology, molecular chaperones are proteins that assist the conformational folding or unfolding of large proteins or macromolecular protein complexes. There are a number of classes of molecular chaperones, all of which function to assi ...

References

Isoflavones Prenylflavonoids Benzodioxoles Resorcinols {{Aromatic-stub