Chlorodehydromethyltestosterone (CDMT; brand name Oral Turinabol), also known as 4-chloro-17β-hydroxy17α-methylandrosta-1,4-dien-3-one, is an
anabolic–androgenic steroid
Anabolic steroids, also known more properly as anabolic–androgenic steroids (AAS), are steroidal androgens that include natural androgens like testosterone as well as synthetic androgens that are structurally related and have similar effects t ...
(AAS). It is the 4-chloro-substituted
derivative of
metandienone (dehydromethyltestosterone).
Side effects
*Chlorodehydromethyltestosterone
History
CDMT was the first original product of
Jenapharm, an
East German pharmaceutical company. It was patented in 1961. The idea of combining the structures of
4-chlorotestosterone (clostebol) and metandienone originated with chemist Albert Stachowiak. At the time, this represented a unique dissociation of
anabolic from
androgenic effects after oral administration.
The product was introduced for clinical use in 1965 and remained in use until 1994, when production was discontinued.
Society and culture
Doping in sports
CDMT was the key steroid administered to approximately ten thousand
East German athletes as part of a secret doping program, known as
State Plan Topic 14.25, often without their knowing the nature of the "vitamins" they were forced to take. The program remained in place from about 1968 until the collapse of the German Democratic Republic in 1989. In the 1990s, Franke and Berendonk examined GDR archives to elucidate the expansive scope of this operation, which had resulted in numerous medal wins and world-record performances.
Following allegations of widespread doping, the
International Olympic Committee reanalyzed samples from the
Beijing 2008 and
London 2012 Olympic Games using the
spectrometric
A spectrometer () is a scientific instrument used to separate and measure spectral components of a physical phenomenon. Spectrometer is a broad term often used to describe instruments that measure a continuous variable of a phenomenon where the ...
method developed by
Grigory Rodchenkov in 2011 for detecting long-lasting metabolites of CDMT.
Weightlifters and
sprinters in particular were found to have used CDMT. Most of the doped athletes came from Russia, Ukraine, and Belarus.
In August 2017,
UFC Light Heavyweight Champion Jon Jones tested positive for turinabol following his victory over
Daniel Cormier at
UFC 214 the month prior.
Colorado Rockies
The Colorado Rockies are an American professional baseball team based in Denver. The Rockies compete in Major League Baseball (MLB) as a member club of the National League (NL) West division. The team plays its home baseball games at Coors Fie ...
third baseman
Colton Welker tested positive in May 2021 while playing for the
Triple-A Albuquerque Isotopes. He was suspended for eighty games.
See also
*
Chlorodehydromethylandrostenediol
*
Chloromethylandrostenediol
References
{{Androgen receptor modulators
Tertiary alcohols
Androgens and anabolic steroids
Androstanes
Hepatotoxins
Enones
Organochlorides
Science and technology in East Germany
World Anti-Doping Agency prohibited substances