Dazucorilant (Cort113176) is an example of a

selective glucocorticoid receptor modulator Selective glucocorticoid receptor modulators (SEGRMs) and selective glucocorticoid receptor agonists (SEGRAs) formerly known as dissociated glucocorticoid receptor agonists (DIGRAs) are a class of experimental drugs designed to share many of th ...

that is in clinical development. It is expected to have uses in the treatment of

neurodegenerative A neurodegenerative disease is caused by the progressive loss of neurons, in the process known as neurodegeneration. Neuronal damage may also ultimately result in their death. Neurodegenerative diseases include amyotrophic lateral sclerosis, mul ...

diseases,

Alzheimer's disease Alzheimer's disease (AD) is a neurodegenerative disease and the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. As the disease advances, symptoms can include problems wit ...

and

Huntington's chorea Huntington's disease (HD), also known as Huntington's chorea, is an incurable neurodegenerative disease that is mostly inherited. It typically presents as a triad of progressive psychiatric, cognitive, and motor symptoms. The earliest sympt ...

, for example.

References

{{Glucocorticoid receptor modulators Selective glucocorticoid receptor modulators Antiglucocorticoids Experimental drugs 4-Fluorophenyl compounds Pyrazoles Sulfonamides 2-Pyridyl compounds Piperidines Heterocyclic compounds with 3 rings

See also

References