
David Gruby (20 August 1810 – 14 November 1898) was a Hungarian
physician
A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through th ...
born in the village of Kis-Kér (now
Bačko Dobro Polje
Bačko Dobro Polje (; hu, Kiskér) is a village in Serbia, in the Autonomous Province of Vojvodina. It is located in the South Bačka District. Administratively it belongs to the municipality of Vrbas. The village has a Serb ethnic majority and ...
, Serbia) to a
Jewish
Jews ( he, יְהוּדִים, , ) or Jewish people are an ethnoreligious group and nation originating from the Israelites Israelite origins and kingdom: "The first act in the long drama of Jewish history is the age of the Israelites""The ...
farmer.
Geoffrey Clough Ainsworth
Geoffrey Clough Ainsworth (9 October 1905 in Birmingham – 25 October 1998 in Derby) was a British mycologist and scientific historian. He was the older brother of Ruth Ainsworth.
Education and work
Ainsworth received his doctorate fr ...
, ''Introduction to the History of Medical and Veterinary Mycology'', Cambridge University Press (2002), p. 13 He received his doctorate in
Vienna
en, Viennese
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and performed scientific research in Paris.
Gruby is remembered as a pioneer in the fields of
microbiology
Microbiology () is the scientific study of microorganisms, those being unicellular (single cell), multicellular (cell colony), or acellular (lacking cells). Microbiology encompasses numerous sub-disciplines including virology, bacteriology, prot ...
and
medical mycology Pathogenic fungi are fungi that cause disease in humans or other organisms. Approximately 300 fungi are known to be pathogenic to humans. Markedly more fungi are known to be pathogenic to plant life than those of the animal kingdom. The study of fu ...
. Most of his important work was done during the 1840s, when he reported that human disease could be caused by fungi.
In 1841 he described the fungus associated with
favus
Favus (Latin for "honeycomb") or tinea favosa is the severe form of tinea capitis, a skin infectious disease caused by the dermatophyte fungus ''Trichophyton schoenleinii.'' Typically the species affects the scalp, but occasionally occurs as onyc ...
, a discovery that was independent of
Johann Lukas Schönlein
Johann Lukas Schönlein (30 November 1793 – 23 January 1864) was a German naturalist, and professor of medicine, born in Bamberg. He studied medicine at Landshut, Jena, Göttingen, and Würzburg. After teaching at Würzburg and Zurich, he was ...
's (1793–1864) findings. Later, the fungal
parasite
Parasitism is a close relationship between species, where one organism, the parasite, lives on or inside another organism, the host, causing it some harm, and is adapted structurally to this way of life. The entomologist E. O. Wilson has ...
was called ''
Achorion
''Achorion'' is an obsolete genus of dermatophyte fungus.
The species previously belonging to genus ''Achorion'' have been moved to other genera. Some notable species include:
* ''A. quinckeanum'' — now named '' Trichophyton quinckeanum'', ...
schoenleinii'' in Schönlein's honor.
In 1842 he described a microscopic
cryptogam
A cryptogam (scientific name Cryptogamae) is a plant (in the wide sense of the word) or a plant-like organism that reproduces by spores, without flowers or seeds. The name ''Cryptogamae'' () means "hidden reproduction", referring to the fact ...
(''Trichophyton ectothrix'') that is associated with a
dermatological
Dermatology is the branch of medicine dealing with the skin.''Random House Webster's Unabridged Dictionary.'' Random House, Inc. 2001. Page 537. . It is a speciality with both medical and surgical aspects. A dermatologist is a specialist medical ...
disease known as ''
sycosis barbae
Sycosis is an inflammation of hair follicles, especially of the beard area,thefreedictionary.com > sycosisciting: Dorland's Medical Dictionary for Health Consumers. 2007thefreedictionary.com > sycosisciting: The American Heritage® Medical Diction ...
''. Gruby also discovered ''
Candida (Monilia) albicans'', the cause of
candidiasis
Candidiasis is a fungal infection due to any type of '' Candida'' (a type of yeast). When it affects the mouth, in some countries it is commonly called thrush. Signs and symptoms include white patches on the tongue or other areas of the mouth ...
, and in 1843 he described a fungus (''
Microsporum audouinii
''Microsporum audouinii'' is an anthropophilic fungus in the genus ''Microsporum''.
It is a type of dermatophyte that colonizes keratinized tissues (primarily hair) causing infection. The fungus is characterized by its spindle-shaped macroconidia ...
'') that is the cause of a type of
ringworm
Dermatophytosis, also known as ringworm, is a fungal infection of the skin. Typically it results in a red, itchy, scaly, circular rash. Hair loss may occur in the area affected. Symptoms begin four to fourteen days after exposure. Multiple a ...
. This fungus was named after
naturalist Jean Victor Audouin (1797–1842).
Gruby also discovered a parasite in the blood of frogs he called ''
Trypanosoma
''Trypanosoma'' is a genus of kinetoplastids (class Trypanosomatidae), a monophyletic group of unicellular parasitic flagellate protozoa. Trypanosoma is part of the phylum Sarcomastigophora. The name is derived from the Greek ''trypano-'' (bore ...
sanguinis''. During the early years of
anaesthesia
Anesthesia is a state of controlled, temporary loss of sensation or awareness that is induced for medical or veterinary purposes. It may include some or all of analgesia (relief from or prevention of pain), paralysis (muscle relaxation), am ...
, he performed important experiments with
chloroform
Chloroform, or trichloromethane, is an organic compound with chemical formula, formula Carbon, CHydrogen, HChlorine, Cl3 and a common organic solvent. It is a colorless, strong-smelling, dense liquid produced on a large scale as a precursor to ...
and
ether
In organic chemistry, ethers are a class of compounds that contain an ether group—an oxygen atom connected to two alkyl or aryl groups. They have the general formula , where R and R′ represent the alkyl or aryl groups. Ethers can again be c ...
on animals.
Associated eponym
* "Gruby's disease":
Tinea capitis
Tinea capitis (also known as "herpes tonsurans", "ringworm of the hair", "ringworm of the scalp", "scalp ringworm", and "tinea tonsurans") is a cutaneous fungal infection (dermatophytosis) of the scalp. The disease is primarily caused by dermatoph ...
in children caused by an infection with ''
Trichophyton tonsurans
''Trichophyton tonsurans'' is a fungus in the family Arthrodermataceae that causes ringworm infection of the scalp. It was first recognized by David Gruby in 1844. Isolates are characterized as the "–" or negative mating type of the '' Arthrode ...
''.
Written works
* ''Mémoire sur une vegétation qui constitue la vraie teigne''. (discovery & description of the achorion of favus)
* ''Recherches anatomiques sun une plante cryptogame qui constitue le vrai muguet des enfants'' (discussion of albidans in
thrush
''The Man from U.N.C.L.E.'' is an American spy fiction television series produced by Metro-Goldwyn-Mayer Television and first broadcast on NBC. The series follows secret agents, played by Robert Vaughn and David McCallum, who work for a secret ...
)
* ''Sur une espèce de mentagre contagieuse résultant du développement d'un nouveau cryptogame dans la racine des poils de la barbe de l'homme''. (description of
Trichophyton
''Trichophyton'' is a genus of fungi, which includes the parasitic varieties that cause tinea, including athlete's foot, ringworm, jock itch, and similar infections of the nail, beard, skin and scalp. Trichophyton fungi are molds characterized ...
mentagrophytes, the cause of sycosis barbae)
* ''Recherches sur la nature, le siège et le développement du Porrigo decalvans ou phytoalopécie'' (concerning the study of Microsporon audouini)
* ''Recherches sur les cryptogames qui constituent la maladie contagieuse du cuir chevelu sous le nom de Teigne'' (''
Trichophyton tonsurans
''Trichophyton tonsurans'' is a fungus in the family Arthrodermataceae that causes ringworm infection of the scalp. It was first recognized by David Gruby in 1844. Isolates are characterized as the "–" or negative mating type of the '' Arthrode ...
'', in ringworm of the scalp).
References
External links
*
''David Gruby''@
Who Named It
''Whonamedit?'' is an online English-language dictionary of medical eponyms and the people associated with their identification. Though it is a dictionary, many eponyms and persons are presented in extensive articles with comprehensive bibliograph ...
{{DEFAULTSORT:Gruby, David
Hungarian Jews
Hungarian dermatologists
Hungarian microbiologists
Jewish microbiologists
Hungarian mycologists
1810 births
1898 deaths
19th-century Hungarian physicians