Daniel Trachsel is a

Swiss Swiss most commonly refers to: * the adjectival form of Switzerland * Swiss people Swiss may also refer to: Places * Swiss, Missouri * Swiss, North Carolina * Swiss, West Virginia * Swiss, Wisconsin Other uses * Swiss Café, an old café located ...

chemist A chemist (from Greek ''chēm(ía)'' alchemy; replacing ''chymist'' from Medieval Latin ''alchemist'') is a graduated scientist trained in the study of chemistry, or an officially enrolled student in the field. Chemists study the composition of ...

who studies

psychedelic Psychedelics are a subclass of hallucinogenic drugs whose primary effect is to trigger non-ordinary mental states (known as psychedelic experiences or "trips") and a perceived "expansion of consciousness". Also referred to as classic halluci ...

s and

entactogen Entactogens, also known as empathogens or connectogens, are a class of psychoactive drugs that induce the production of experiences of emotional communion, oneness, connectedness, emotional openness—that is, empathy—as particularly observe ...

s. He has developed and published on a large number of novel psychedelic and entactogen

compound Compound may refer to: Architecture and built environments * Compound (enclosure), a cluster of buildings having a shared purpose, usually inside a fence or wall ** Compound (fortification), a version of the above fortified with defensive struc ...

s, including their

psychoactive A psychoactive drug, psychopharmaceutical, mind-altering drug, consciousness-altering drug, psychoactive substance, or psychotropic substance is a chemical substance that alters psychological functioning by modulating central nervous system acti ...

effects. This has been in a manner similar to that of the psychedelic chemist

Alexander Shulgin Alexander Theodore "Sasha" Shulgin (June 17, 1925 – June 2, 2014) was an American biochemist, broad researcher of synthetic psychoactive compounds, and author of works regarding these, who independently explored the organic chemistry and ph ...

, which has caused Trachsel to sometimes be referred to as the "German Shulgin". However, unlike Shulgin, Trachsel has distanced himself from any personal

self-experiment Self-experimentation refers to single-subject research in which the experimenter conducts the experiment on themself. Usually this means that a single person is the designer, operator, subject, analyst, and user or reporter of the experiment. Al ...

s. According to

Hamilton Morris Hamilton Morris (born April 14, 1987) is an American journalist, documentarian, and scientific researcher. He is the creator and director of the television series ''Hamilton's Pharmacopeia'', in which he investigated the chemistry, history, and ...

and Nick Cozzi in mid-2023, Trachel's book ''Phenethylamine: von der Struktur zur Funktion'' (''Phenethylamines: From Structure to Function'') is in the process of being translated into English. It is being independently translated by the

Alexander Shulgin Research Institute Alexander Shulgin Research Institute (ASRI) is an organization developing novel psychedelic and entactogen drugs as potential pharmaceuticals, among other activities. Its goal is to advance the scientific work and legacy of psychedelic chemist Al ...

(ASRI), with tentative publication by

Transform Press Transform Press is a small publishing company in the area of psychedelics and other psychoactive drugs that is based in Berkeley, California.In Memoriam Ann Shulgin, Forerunner of Today’s Psychedelic Re-Emergence, Dies at 91. MAPS Bulletin: Spec ...

, and also by chemist David Carlson.

Compounds

Compounds that were first known to have been synthesized by Trachsel and colleagues include: *

2C-BI-8 2C-BI-8, also known as 2,5-dimethoxy-4-(4-methoxyphenyl)phenethylamine or as 4′-methoxy-2C-Ph, is a serotonin receptor agonist of the phenethylamine and 2C families. It is the derivative of 2C-Ph (2C-BI-1) with a methoxy group at the 4 positio ...

2C-CP 2C-CP (2C-cP) is a recreational designer drug from the substituted phenethylamine family, with psychedelic effects. It was first synthesised by Daniel Trachsel and colleagues in 2006. It has a binding affinity (Ki) of 95 nM at the serotonin ...

2C-Ph 2C-Ph, also known as 2C-BI-1 or as 2,5-dimethoxy-4-phenylphenethylamine, is a serotonin receptor modulator of the phenethylamine and 2C families that was developed by Daniel Trachsel and David E. Nichols and colleagues. The drug's affinity (Ki) ...

(2C-BI-1) *

2C-T-3 2C-T-3, also initially numbered as 2C-T-20 and also known as 4-methallylthio-2,5-dimethoxyphenethylamine, is a lesser-known psychedelic drug related to compounds such as 2C-T-7 and 2C-T-16. It was named by Alexander Shulgin but was never made or t ...

2C-T-16 2C-T-16, also known as 4-allylthio-2,5-dimethoxyphenethylamine, is a lesser-known psychedelic drug. It was originally named by Alexander Shulgin as described in his book PiHKAL (Phenethylamines i Have Known And Loved), however while Shulgin bega ...

2C-T-21.5 2C-T-21.5, also known as 4-(2,2-difluoroethylthio)-2,5-dimethoxyphenethylamine, is a lesser-known psychedelic drug related to compounds such as 2C-T-21 and 2C-T-28. It was originally named by Alexander Shulgin and discussed in his book PiHKAL, b ...

* 2C-T-25 *

2C-T-27 2C-T-27, also known as 4-benzylthio-2,5-dimethoxyphenethylamine, is a serotonin 5-HT2A receptor agonist and serotonergic psychedelic of the phenethylamine and 2C families. It was first synthesized and described by Daniel Trachsel in 2003. In a ...

2C-T-28 2C-T-28, also known as 4-(3-fluoropropylthio)-2,5-dimethoxyphenethylamine, is a lesser-known psychedelic drug related to compounds such as 2C-T-7 and 2C-T-21. It was named by Alexander Shulgin but was never made or tested by him, and was instead ...

* 2C-T-30 * 2C-T-31 * 2C-T-32 *

2C-T-33 2C-T-33, also known as 4-(3-methoxybenzylthio)-2,5-dimethoxyphenethylamine, is a serotonin receptor agonist of the phenethylamine and 2C families. It was first synthesized and described by Daniel Trachsel in 2003. The drug is not known to have ...

2C-TFE 2C-TFE is a lesser-known psychedelic drug related to compounds such as 2C-E and 2C-TFM. It was first synthesised by Daniel Trachsel, and is reportedly a potent psychedelic with an active dose in the 5–15 mg range, and a long duration of ac ...

2C-V 2C-V is a recreational designer drug from the substituted phenethylamine family, with psychedelic effects. It was first synthesised by Daniel Trachsel and colleagues in 2006. It is active at a dosage of 25 mg with a duration of around 5 hour ...

2C-YN 2C-YN is an analog of phenethylamine that can be synthesized from 2C-I. Very little data exists about the pharmacological properties, metabolism, and toxicity of 2C-YN, although Daniel Trachsel lists it as having a dosage of around 50mg and a d ...

3C-DFE 3C-DFE is a lesser-known psychedelic drug, which is a fluorinated derivative of 3C-E. It was first synthesised by Daniel Trachsel in 2002, and has been reported as showing similar psychedelic activity to related compounds, with a dose range of ar ...

DFMDA Difluoromethylenedioxyamphetamine (DFMDA, DiFMDA) is a substituted derivative of 3,4-methylenedioxyamphetamine (MDA), which was developed by Daniel Trachsel and coworkers, along with the corresponding fluorinated derivatives of MDMA, MDEA, BDB a ...

Trifluoromescaline Trifluoromescaline (TF-M) is a derivative of the phenethylamine hallucinogen mescaline, which has a trifluoromethoxy group replacing the central methoxy group of mescaline. Trifluoromescaline was found to be one of the most potent compounds in t ...

Selected publications

Books

* ote: There are also several subsequent editions (2nd (2002) through 5th (2016)).ref name="WorldCat"> *

Papers

* * * * * * * * *

References

{{DEFAULTSORT:Trachsel, Daniel Living people Psychedelic drug researchers Swiss chemists University of Bern alumni Year of birth missing (living people)

Compounds

Selected publications

Books

Papers

See also

References