DCG-IV is a research drug which acts as a group-selective agonist for the group II metabotropic glutamate receptors (
mGluR2/ 3).
It has potent
neuroprotective
Neuroprotection refers to the relative preservation of neuronal structure and/or function. In the case of an ongoing insult (a neurodegenerative insult) the relative preservation of neuronal integrity implies a reduction in the rate of neuronal los ...
and
anticonvulsant
Anticonvulsants (also known as antiepileptic drugs or recently as antiseizure drugs) are a diverse group of pharmacological agents used in the treatment of epileptic seizures. Anticonvulsants are also increasingly being used in the treatment of ...
effects in animal studies,
as well as showing anti-
Parkinsonian effects,
but also impairs the formation of memories.
References
Anticonvulsants
Amino acids
Tricarboxylic acids
Cyclopropanes
MGlu2 receptor agonists
MGlu3 receptor agonists
{{anticonvulsant-stub