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DBL-583 is a selective
dopamine reuptake inhibitor A dopamine reuptake inhibitor (DRI) is a class of drug which acts as a reuptake inhibitor of the monoamine neurotransmitter dopamine by blocking the action of the dopamine transporter (DAT). Reuptake inhibition is achieved when extracellular dop ...
of the
piperazine Piperazine () is an organic compound with the formula . In term of its structure, it can be described as cyclohexane with the 1- and 4-CH2 groups replaced by NH. Piperazine exists as deliquescent solid with a saline taste. Piperazine is freely sol ...
chemical class Chemical classification systems attempt to classify elements or compounds according to certain chemical functional or structural properties. Whereas the structural properties are largely intrinsic, functional properties and the derived classi ...
. It is the decanoate
ester In chemistry, an ester is a compound derived from an acid (either organic or inorganic) in which the hydrogen atom (H) of at least one acidic hydroxyl group () of that acid is replaced by an organyl group (R). These compounds contain a distin ...
of a hydroxy
vanoxerine Vanoxerine is an investigational drug which is being evaluated for the treatment of heart arrhythmias and cocaine dependence. Vanoxerine is a piperazine derivative which has multiple pharmacological activities including acting as an dopamine re ...
. DBL-583 breaks down very slowly in the body, lasting for up to a month after a single injection.


See also

*
GBR-12783 GBR-12783 is a psychostimulant which acts as a selective dopamine reuptake inhibitor. See also * Vanoxerine * GBR-12935 * GBR-13069 * GBR-13098 * DBL-583 *LR-1111 LR-1111 is an analog of GBR-12935 that was discovered by Richard Rothman and ...
*
GBR-12935 GBR-12935 is a piperazine derivative which is a potent and selective dopamine reuptake inhibitor. It was originally developed in its tritium, 3H isotopic labelling, radiolabelled form for the purpose of mapping the distribution of dopaminergic n ...
*
GBR-13069 GBR-13069 is a psychostimulant and selective dopamine reuptake inhibitor. See also * Vanoxerine * GBR-12783 * GBR-12935 * GBR-13098 * DBL-583 *LR-1111 LR-1111 is an analog of GBR-12935 that was discovered by Richard Rothman and co-workers in ...
*
GBR-13098 GBR-13098 is a psychostimulant and selective dopamine uptake inhibitor. Blocking the endogenous striatal dopamine (DA) transporter with GBR-13098 in mice has been shown to prevent damage to the DA nerve terminals caused by malonate. It was sugge ...


References

Decanoate esters Dopamine_reuptake_inhibitors 1-(2-(Bis(4-fluorophenyl)methoxy)ethyl)piperazines {{nervous-system-drug-stub