Cyril Norman Hugh Long
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Cyril Norman Hugh Long (June 19, 1901 – July 6, 1970) was an English-American
biochemist Biochemists are scientists who are trained in biochemistry. They study chemical processes and chemical transformations in living organisms. Biochemists study DNA, proteins and Cell (biology), cell parts. The word "biochemist" is a portmanteau of ...
and academic administrator. He was
Sterling Professor Sterling Professor, the highest academic rank at Yale University, is awarded to a Academic tenure in North America, tenured faculty member considered the best in their field. It is akin to the rank of distinguished professor at other universities. ...
of
physiological chemistry Biochemistry, or biological chemistry, is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology, a ...
at
Yale University Yale University is a Private university, private Ivy League research university in New Haven, Connecticut, United States. Founded in 1701, Yale is the List of Colonial Colleges, third-oldest institution of higher education in the United Stat ...
for 31 years during the middle part of the 20th century.


Background

Cyril Long was born in Burton, Nettleton, Wiltshire, the first of two sons of John Edward Long and Rose Fanny Long, née Langward. As a young man, he did not plan to study to become a scientist. He instead experimented with diverse areas such as perfume making and working with wood. Long devoted much of his time to literature and history. As a child he enjoyed playing soccer and cricket and many times his father needed to remind him to come back home to study. He always performed well during his school years and was ranked among the best of his graduating class. He appeared to have a natural talent for chemistry and once said, "I was attracted from an early age to chemistry, largely by my own fortunate contact in an English school with a science master ... whose ways of teaching it was so effective that a large number of his students have become scientists". Long studied
organic chemistry Organic chemistry is a subdiscipline within chemistry involving the science, scientific study of the structure, properties, and reactions of organic compounds and organic matter, organic materials, i.e., matter in its various forms that contain ...
under Robert Robinson and
Arthur Lapworth Arthur Lapworth FRS (10 October 1872 – 5 April 1941) was a Scottish chemist. He studied the mechanisms and kinetics of organic reactions. His most cited work was on the bromination of acetone published in 1904. He served as a professor of inor ...
at the
University of Manchester The University of Manchester is a public university, public research university in Manchester, England. The main campus is south of Manchester city centre, Manchester City Centre on Wilmslow Road, Oxford Road. The University of Manchester is c ...
, where he received his BSc. Shortly after his graduation in 1921, he began assisting Nobel laureate A. V. Hill in his work on the biophysics of muscle contraction. After working for two years at
University College London University College London (Trade name, branded as UCL) is a Public university, public research university in London, England. It is a Member institutions of the University of London, member institution of the Federal university, federal Uni ...
, Long sailed on 4 September 1925 on the RMS Aurania from Liverpool to Quebec, to work in
Montreal Montreal is the List of towns in Quebec, largest city in the Provinces and territories of Canada, province of Quebec, the List of the largest municipalities in Canada by population, second-largest in Canada, and the List of North American cit ...
with Jonathan Meakins at
McGill University McGill University (French: Université McGill) is an English-language public research university in Montreal, Quebec, Canada. Founded in 1821 by royal charter,Frost, Stanley Brice. ''McGill University, Vol. I. For the Advancement of Learning, ...
; he received his
M.D. A Doctor of Medicine (abbreviated MD, from the Latin ) is a medical degree, the meaning of which varies between different jurisdictions. In the United States, and some other countries, the ''MD'' denotes a professional degree of physician. This ge ...
there in 1928. He served as director of the George S. Cox Medical Research Institute, a diabetes research center at the
University of Pennsylvania The University of Pennsylvania (Penn or UPenn) is a Private university, private Ivy League research university in Philadelphia, Pennsylvania, United States. One of nine colonial colleges, it was chartered in 1755 through the efforts of f ...
. In 1936, Long moved to the
School of Medicine A medical school is a tertiary educational institution, professional school, or forms a part of such an institution, that teaches medicine, and awards a professional degree for physicians. Such medical degrees include the Bachelor of Medicine, ...
. At Yale, he was Director of the Division of Biological Sciences (1939–42), Dean of the School of Medicine (1947–52), and Chair of Physiology (1951–64). In the 1930s and 1940s Long and Abraham White worked together in the Yale Medical Center. As a result of their and Hubert R Catchpole's work in 1937 they isolated bovine prolactin, the first of the
protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metab ...
pituitary The pituitary gland or hypophysis is an endocrine gland in vertebrates. In humans, the pituitary gland is located at the base of the brain, protruding off the bottom of the hypothalamus. The pituitary gland and the hypothalamus control much of th ...
hormones A hormone (from the Greek participle , "setting in motion") is a class of signaling molecules in multicellular organisms that are sent to distant organs or tissues by complex biological processes to regulate physiology and behavior. Hormones a ...
to be obtained in pure
crystal A crystal or crystalline solid is a solid material whose constituents (such as atoms, molecules, or ions) are arranged in a highly ordered microscopic structure, forming a crystal lattice that extends in all directions. In addition, macros ...
line form. Later, they isolated different hormones, and later characterized and
sequenced In genetics and biochemistry, sequencing means to determine the primary structure (sometimes incorrectly called the primary sequence) of an unbranched biopolymer. Sequencing results in a symbolic linear depiction known as a sequence which succi ...
many of them, greatly contributing to modern
biochemistry Biochemistry, or biological chemistry, is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology, a ...
. Long mainly worked with the hormones of the pituitary gland and adrenal extracts of the
metabolism Metabolism (, from ''metabolē'', "change") is the set of life-sustaining chemical reactions in organisms. The three main functions of metabolism are: the conversion of the energy in food to energy available to run cellular processes; the co ...
; his major research goal was to find a cure for
diabetes Diabetes mellitus, commonly known as diabetes, is a group of common endocrine diseases characterized by sustained high blood sugar levels. Diabetes is due to either the pancreas not producing enough of the hormone insulin, or the cells of th ...
. Long was elected to the United States
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, NGO, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the ...
in 1948 and a member of both the
American Philosophical Society The American Philosophical Society (APS) is an American scholarly organization and learned society founded in 1743 in Philadelphia that promotes knowledge in the humanities and natural sciences through research, professional meetings, publicat ...
and the
American Academy of Arts and Sciences The American Academy of Arts and Sciences (The Academy) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and other ...
in 1949. Long married Hilda Gertrude Jarman in Kerrisdale, Vancouver on 28 July 1928.,British Columbia, Canada, Marriage Index, 1872-1935 and they had two daughters: Diana Elizabeth Long (Diana Long Hall), a historian of science and medicine, and Barbara Rosemary Long. Long was naturalised on 1 July 1942, and Hilda on 19 November 1948, while they were living at 100 Old Farm Road,
Hamden, Connecticut Hamden is a New England town, town in New Haven County, Connecticut, United States. The town's nickname is "The Land of the Sleeping Giant (Connecticut), Sleeping Giant". The town is part of the South Central Connecticut Planning Region, Connecti ...
. Cyril Norman Hugh Long died on 6 July 1970, aged 69. Hilda died on 16 October 1988, aged 76. They are both buried at
Grove Street Cemetery Grove Street Cemetery or Grove Street Burial Ground is a cemetery in New Haven, Connecticut, that is surrounded by the Yale University campus. It was organized in 1796 as the New Haven Burying Ground and incorporated in October 1797 to replace th ...
, New Haven, Connecticut.


References

{{DEFAULTSORT:Long, Cyril Norman Hugh 1901 births 1970 deaths Yale School of Medicine faculty People from Wiltshire Yale Sterling Professors British emigrants to the United States Members of the American Philosophical Society