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Curdlan is a water-insoluble linear beta-1,3-
glucan A glucan is a polysaccharide derived from D-glucose, linked by glycosidic bonds. Glucans are noted in two forms: alpha glucans and beta glucans. Many beta-glucans are medically important. They represent a drug target for antifungal medications of ...
, a high-molecular-weight polymer of glucose. Curdlan consists of β-(1,3)-linked glucose residues and forms elastic gels upon heating in aqueous suspension. It was reported to be produced by '' Alcaligenes faecalis'' var. ''myxogenes''. Subsequently, the taxonomy of this non-pathogenic curdlan-producing bacterium has been reclassified as '' Agrobacterium'' species. Extracellular and capsular polysaccharides are produced by a variety of pathogenic and soil-dwelling bacteria. Curdlan is a neutral β-(1,3)-glucan, perhaps with a few intra- or interchain 1,6-linkages, produced as an exopolysaccharide by soil bacteria of the family Rhizobiaceae. Four genes required for curdlan production have been identified in '' Agrobacterium'' sp. ATCC31749, which produces curdlan in extraordinary amounts, and ''
Agrobacterium tumefaciens ''Agrobacterium radiobacter'' (more commonly known as ''Agrobacterium tumefaciens'') is the causal agent of crown gall disease (the formation of tumours) in over 140 species of eudicots. It is a rod-shaped, Gram-negative soil bacterium. Sympto ...
''. A putative operon contains crdS
Q9X2V0
family GT2, ), encoding β-(1,3)-glucan synthase catalytic subunit, flanked by two additional genes. A separate locus contains a putative regulatory gene, crdR. A membrane-bound phosphatidylserine synthase, encoded by pssAG, is also necessary for maximal production of curdlan of high molecular mass. Nitrogen starvation upregulates the curdlan operon and increases the rate of curdlan synthesis. Curdlan has numerous applications as a gelling agent in the food, construction, and pharmaceutical industries and has been approved as a food additive by the U. S. Food and Drug Administration. Its use is being evaluated in fat replacement studies in foodstuffs such as sausages, meat patties and other meat products


See also

* Callose * Gellan gum


References

{{Reflist Polysaccharides