Cornelia "Nina" Channing (1938–1985) was an American professor of

physiology Physiology (; ) is the science, scientific study of function (biology), functions and mechanism (biology), mechanisms in a life, living system. As a branches of science, subdiscipline of biology, physiology focuses on how organisms, organ syst ...

at the

University of Maryland School of Medicine The University of Maryland School of Medicine (abbreviated UMSOM), located in Baltimore City, Maryland, U.S., is the medical school of the University of Maryland, Baltimore and is affiliated with the University of Maryland Medical Center and ...

. Her research focused on

endocrinology Endocrinology (from ''endocrine system, endocrine'' + ''wikt:-logy#Suffix, -ology'') is a branch of biology and medicine dealing with the endocrine system, its diseases, and its specific secretions known as hormones. It is also concerned with the ...

and

fertility Fertility in colloquial terms refers the ability to have offspring. In demographic contexts, fertility refers to the actual production of offspring, rather than the physical capability to reproduce, which is termed fecundity. The fertility rate ...

; along with longtime collaborators

Neena Schwartz Neena Betty Schwartz (December 10, 1926 – April 15, 2018) was an American endocrinologist and William Deering Professor of Endocrinology Emerita in the Department of Neurobiology at Northwestern University. She was best known for her work on ...

and Darrell Ward, she was involved in the discovery of

hormone A hormone (from the Ancient Greek, Greek participle , "setting in motion") is a class of cell signaling, signaling molecules in multicellular organisms that are sent to distant organs or tissues by complex biological processes to regulate physio ...

s involved in regulating the female reproductive cycle. She died of

breast cancer Breast cancer is a cancer that develops from breast tissue. Signs of breast cancer may include a Breast lump, lump in the breast, a change in breast shape, dimpling of the skin, Milk-rejection sign, milk rejection, fluid coming from the nipp ...

in 1985.

Early life and education

Channing was born in

Boston, Massachusetts Boston is the capital and most populous city in the Commonwealth (U.S. state), Commonwealth of Massachusetts in the United States. The city serves as the cultural and Financial centre, financial center of New England, a region of the Northeas ...

in 1938. She received her bachelor's degree from

Hood College Hood College is a private college in Frederick, Maryland. In fall 2018, Hood enrolled 2,052 students (1,092 undergraduate students; 960 graduate students). Thirty-eight percent of students are either members of under-represented racial or ethni ...

in 1961 and her PhD in

biochemistry Biochemistry, or biological chemistry, is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology, a ...

from

Harvard Medical School Harvard Medical School (HMS) is the medical school of Harvard University and is located in the Longwood Medical and Academic Area, Longwood Medical Area in Boston, Massachusetts. Founded in 1782, HMS is the third oldest medical school in the Un ...

in 1965, advised by Claude Villee. She worked as a

postdoctoral fellow A postdoctoral fellow, postdoctoral researcher, or simply postdoc, is a person professionally conducting research after the completion of their doctoral studies (typically a PhD). Postdocs most commonly, but not always, have a temporary academ ...

Cambridge Cambridge ( ) is a List of cities in the United Kingdom, city and non-metropolitan district in the county of Cambridgeshire, England. It is the county town of Cambridgeshire and is located on the River Cam, north of London. As of the 2021 Unit ...

Academic career

Channing returned to the US to serve as an instructor and later an

assistant professor Assistant professor is an academic rank just below the rank of an associate professor used in universities or colleges, mainly in the United States, Canada, Japan, and South Korea. Overview This position is generally taken after earning a doct ...

at the

University of Pittsburgh The University of Pittsburgh (Pitt) is a Commonwealth System of Higher Education, state-related research university in Pittsburgh, Pennsylvania, United States. The university is composed of seventeen undergraduate and graduate schools and colle ...

, where she spent seven years in total. In 1973 she moved to the

University of Maryland The University of Maryland, College Park (University of Maryland, UMD, or simply Maryland) is a public land-grant research university in College Park, Maryland, United States. Founded in 1856, UMD is the flagship institution of the Univ ...

as an associate professor and was promoted to

full professor Professor (commonly abbreviated as Prof.) is an academic rank at universities and other post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin as a 'person who professes'. Professors ...

in 1976. Channing served on the board of directors of the

Society for the Study of Reproduction The Society for the Study of Reproduction (SSR) is an international not-for-profit professional society for scientists working in the fields of reproduction, fertility and development. The Society focuses on reproduction in both people and anim ...

in 1978-80 and was the recipient of its first Research Award in 1978. Channing was a close collaborator of endocrinologist

, whose work on their shared research interests continued after Channing's death; along with other researchers including Darrell Ward, they identified the

peptide hormone Peptide hormones are hormones composed of peptide molecules. These hormones influence the endocrine system of animals, including humans. Most hormones are classified as either amino-acid-based hormones (amines, peptides, or proteins) or steroid h ...

inhibin Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Identified in 1986, activin enhances FSH biosynthesis and secretion, and participates in the regulation of the menstrual c ...

and worked out molecular mechanisms of hormonal signaling in the female

reproductive cycle In biology, a biological life cycle (or just life cycle when the biological context is clear) is a series of stages of the life of an organism, that begins as a zygote, often in an egg, and concludes as an adult that reproduces, producing an offsp ...

. Channing's interest in the biology of reproduction was motivated in part by an interest in

contraceptive Birth control, also known as contraception, anticonception, and fertility control, is the use of methods or devices to prevent pregnancy. Birth control has been used since ancient times, but effective and safe methods of birth control only be ...

research.

References

{{DEFAULTSORT:Channing, Cornelia 1938 births 1985 deaths American endocrinologists American women endocrinologists University of Maryland, Baltimore faculty Harvard Medical School alumni Hood College alumni 20th-century American physicians Biologists from Massachusetts 20th-century American women academics 20th-century American academics