Consed
is a program for viewing, editing, and finishing DNA
sequence assemblies. Originally developed for sequence assemblies created with
phrap, recent versions also support other sequence assembly programs like Newbler.
History
Consed was originally developed as a contig editing and finishing tool for large-scale cosmid shotgun sequencing in the
Human Genome Project
The Human Genome Project (HGP) was an international scientific research project with the goal of determining the base pairs that make up human DNA, and of identifying, mapping and sequencing all of the genes of the human genome from both a ...
. At genome sequencing centers, Consed was used to check assemblies generated by
phrap, solve assembly problems like those caused by highly identical repeats, and finishing tasks like primer picking and gap closure.
Development of Consed has continued after the completion of the
Human Genome Project
The Human Genome Project (HGP) was an international scientific research project with the goal of determining the base pairs that make up human DNA, and of identifying, mapping and sequencing all of the genes of the human genome from both a ...
. Current Consed versions support very large projects with millions of reads, enabling the use with newer sequencing methods like
454 sequencing and
Solexa sequencing. Consed also has advanced tools for finishing tasks like automated primer picking
See also
*
Phred
*
Phrap
References
External links
Consed homepage
Bioinformatics
Computational science
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