The conflict procedure is an experiment often used in
scientific research
The scientific method is an empirical method for acquiring knowledge that has characterized the development of science since at least the 17th century (with notable practitioners in previous centuries; see the article history of scientific ...
to quantify
anxiety
Anxiety is an emotion which is characterized by an unpleasant state of inner turmoil
Turmoil may refer to:
* ''Turmoil'' (1984 video game), a 1984 video game released by Bug-Byte
* ''Turmoil'' (2016 video game), a 2016 indie oil tycoon video ...
levels by measuring changes in punished/unpunished responses. It is often used to screen
drug
A drug is any chemical substance that causes a change in an organism's physiology or psychology when consumed. Drugs are typically distinguished from food and substances that provide nutritional support. Consumption of drugs can be via inhal ...
s for their potential to inhibit anxiety (
anxiolytic
An anxiolytic (; also antipanic or antianxiety agent) is a medication or other intervention that reduces anxiety. This effect is in contrast to anxiogenic agents which increase anxiety. Anxiolytic medications are used for the treatment of anxie ...
potential).
Study
Some researchers from France have conducted an experiment on "Effects of Chronic Antidepressants in an Operant Conflict Procedure of Anxiety in the rat (1998)", "the aim of their study was to reveal possible anxiolytic like effects of antidepressants during ongoing treatment. Rats were subjected to a conflict procedure during which lever pressing for food was suppressed by a conditioned signal for punishment and contingent electric foot shocks."
[Beaufour, C. C., Ballon, N., Le Bihan, C., Hamon, M., & Thiébot, M. (1999). Effects of chronic antidepressants in an operant conflict procedure of anxiety in the rat. Pharmacology, Biochemistry And Behavior, 62(4), 591-599]
doi:10.1016/S0091-3057(98)00180-4
/ref> In the preparatory phase of the experiment, researchers increased anxiety using electrical shocks on rats gradually over a several week long training process. They then administered the chosen drug and observed how it altered the responses of the rats.
See also
* Forced swim test
The behavioural despair test (or Porsolt forced swimming test) is a test, centered on a rodent's response to the threat of drowning, whose result has been interpreted as measuring susceptibility to negative mood. It is commonly used to measure the ...
References
Animal testing
Psychology experiments
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