Complement component 1s (, ''
C1 esterase
C1, C01, C.I or C-1 may refer to:
Arts and media
* C1, a note-octave in music
* C1 Television, a Mongolian television channel
* Schecter C-1 Hellraiser FR, a guitar model
* A Yamaha grand piano model
* "C1", a slang expression in the video gam ...
'', ''activated complement C1s'', ''complement C overbar 1r'', ''C1s'') is a
protein involved in the
complement system
The complement system, also known as complement cascade, is a part of the immune system that enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promote inflammation, and at ...
. C1s is part of the
C1 complex. In humans, it is encoded by the ''C1S''
gene.
C1s cleaves
C4 and
C2, which eventually leads to the production of the
classical pathway
C3-convertase.
See also
*
C1q - another part of the
C1 complex
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C1r - another part of the C1 complex
*
MASP-2 - a protein similar to C1s, part of the
lectin pathway
References
Further reading
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External links
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Complement system
EC 3.4.21
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