In
medicine
Medicine is the science and Praxis (process), practice of caring for patients, managing the Medical diagnosis, diagnosis, prognosis, Preventive medicine, prevention, therapy, treatment, Palliative care, palliation of their injury or disease, ...
, the Comorbidity–polypharmacy score (CPS) is a measure of overall severity of comorbidities. It is defined as the simple sum of the number of known
comorbidities
In medicine, comorbidity refers to the simultaneous presence of two or more medical conditions in a patient; often co-occurring (that is, concomitant or concurrent) with a primary condition. It originates from the Latin term (meaning "sickness" ...
(concurrent conditions) and pre-admission medications taken by the patient (
polypharmacy
Polypharmacy (polypragmasia) is an umbrella term to describe the simultaneous use of multiple medicines by a patient for their conditions. The term polypharmacy is often defined as regularly taking five or more medicines but there is no standard ...
), as a surrogate for the “intensity” of the comorbidities.
This score has been tested and validated extensively in the
trauma
Trauma most often refers to:
*Psychological trauma, in psychology and psychiatric medicine, refers to severe mental and emotional injury caused by distressing events
*Traumatic injury, sudden physical injury caused by an external force, which doe ...
population, demonstrating good correlation with mortality, morbidity, triage, and hospital readmissions.
Increasing levels of CPS were associated with significantly lower 90-day survival in the original study of the score in trauma population.
Comparison with other comorbidity measures
The test is similar to the
Charlson Comorbidity Index (CCI), but CPS also considers the number of medications taken, which is not a parameter in CCI. Additionally, CPS considers a wider range of comorbidities than CCI, and assigns the same weight to each.
A study comparing the two metrics found that CCI was a better predictor of mortality than CPS in older trauma patients.
See also
*
Comorbidity
In medicine, comorbidity refers to the simultaneous presence of two or more medical conditions in a patient; often co-occurring (that is, concomitant or concurrent) with a primary condition. It originates from the Latin term (meaning "sicknes ...
*
Charlson Comorbidity Index (CCI)
*
Elixhauser Comorbidity Index
References
Medical diagnosis
Comorbidity measures
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