Cloxestradiol (), also known as 17-(2,2,2-trichloroethoxy)estradiol, is a
synthetic
Synthetic may refer to:
Science
* Synthetic biology
* Synthetic chemical or compound, produced by the process of chemical synthesis
* Synthetic elements, chemical elements that are not naturally found on Earth and therefore have to be created in ...
,
steroid
A steroid is an organic compound with four fused compound, fused rings (designated A, B, C, and D) arranged in a specific molecular configuration.
Steroids have two principal biological functions: as important components of cell membranes t ...
al
estrogen
Estrogen (also spelled oestrogen in British English; see spelling differences) is a category of sex hormone responsible for the development and regulation of the female reproductive system and secondary sex characteristics. There are three ...
which was never marketed.
It is an
analogue of
estradiol
Estradiol (E2), also called oestrogen, oestradiol, is an estrogen steroid hormone and the major female sex hormone. It is involved in the regulation of female reproductive cycles such as estrous and menstrual cycles. Estradiol is responsible ...
with a 2,2,2-trichloroethoxy substitution.
The ''O'',''O''-diacetate derivative,
cloxestradiol acetate (brand name Genovul), has been marketed as an estrogen.
See also
*
List of estrogens
This is a list of steroidal estrogen (medication), estrogens or derivative (chemistry), derivatives of estradiol (medication), estradiol, estrone, and estriol. Most esters of these estrogens are not included in this list; for esters, see List of ...
*
List of estrogen esters
This is a list of estrogen esters, or ester prodrugs of estrogens. It includes esters, as well as ethers, of steroidal estrogens like estradiol, estrone, and estriol and of nonsteroidal estrogens like the stilbestrols diethylstilbestrol and hexes ...
References
Abandoned drugs
Sterols
Hydroxyarenes
Estranes
Estrogen ethers
Synthetic estrogens
Trichloromethyl compounds
{{Steroid-stub